Results 31 to 40 of about 405,820 (287)

Analysis of amino acid motif of penicillin-binding proteins 1a, 2b, and 2x in invasive Streptococcus pneumoniae nonsusceptible to penicillin isolated from pediatric patients in Casablanca, Morocco

BMC Research Notes, 2018
Objectives This study aimed to investigate the nature of the amino acid motifs found in PBPs of Streptococcus pneumoniae isolates in invasive diseases from pediatric patients at Casablanca, Morocco.
Idrissa Diawara, Kaotar Nayme, Khalid Katfy, Abouddihaj Barguigua, Mohamed Kettani-Halabi, Houria Belabbes, Mohammed Timinouni, Khalid Zerouali, Naima Elmdaghri   +8 more
doaj   +1 more source

Enzymatic activity of poliovirus RNA polymerase mutants with single amino acid changes in the conserved YGDD amino acid motif [PDF]

Journal of Virology, 1991
RNA-dependent RNA polymerases contain a highly conserved region of amino acids with a core segment composed of the amino acids YGDD which have been hypothesized to be at or near the catalytic active site of the molecule. Six mutations in this conserved YGDD region of the poliovirus RNA-dependent RNA polymerase were made by using oligonucleotide site ...
S A, Jablonski, M, Luo, C D, Morrow
openaire   +2 more sources

Global Variability of V3 Loop Tetrapeptide Motif: a Concern for HIV-1 Neutralizing Antibodies-based Vaccine Design and Antiretroviral Therapy

Journal of Medical Microbiology and Infectious Diseases, 2021
Introduction: HIV-1 gp120 V3 GPGR motif has an essential role in viral invasion, cell fusion, and pathogenesis but presents a significant variability that can implicate neutralizing antibodies and antiretroviral drug resistance.
Luciano Rodrigo Lopes, Antonio Carlos da Silva Junior, Paulo Bandiera-Paiva, Jorge Casseb   +3 more
doaj   +1 more source

Identification of nuclear localization signal and nuclear export signal of VP1 from the chicken anemia virus and effects on VP2 shuttling in cells

Virology Journal, 2019
Background VP1 of the chicken anemia virus (CAV) is a structural protein that is required for virus encapsulation. VP1 proteins are present both in the nucleus and cytoplasm; however, the functional nuclear localization signal (NLS) and nuclear export ...
Jai-Hong Cheng, Guan-Hua Lai, Yi-Yang Lien, Fang-Chun Sun, Shan-Ling Hsu, Pei-Chin Chuang, Meng-Shiou Lee   +6 more
doaj   +1 more source

Differences in collagen prolyl 4-hydroxylase assembly between two Caenorhabditis nematode species despite high amino acid sequence identity of the enzyme subunits [PDF]

, 2007
The collagen prolyl 4-hydroxylases (P4Hs) are essential for proper extracellular matrix formation in multicellular organisms. The vertebrate enzymes are α2β2 tetramers, in which the β subunits are identical to protein disulfide ...
Abrams, Alan D. Winter, Annunen, Annunen, Annunen, Antony P. Page, Bessereau, Crossen, D'Andrea, Friedman, Gillian McCormack, Helaakoski, Hieta, Hill, Johanna Myllyharju, John, Katriina Keskiaho, Kivirikko, Kivirikko, Kukkola, Lamberg, Liisa Kukkola, Marie-Anne Felix, Merriweather, Myllyharju, Myllyharju, Myllyharju, Myllyharju, Myllyharju, Myllyharju, Nissi, Page, Pekkala, Quevillon, Riihimaa, Stein, Sulston, Thein, Van den Diepstraten, Veijola, Veijola, Vuori, Williams, Winter, Winter   +44 more
core   +1 more source

rMotifGen: random motif generator for DNA and protein sequences

BMC Bioinformatics, 2007
Background Detection of short, subtle conserved motif regions within a set of related DNA or amino acid sequences can lead to discoveries about important regulatory domains such as transcription factor and DNA binding sites as well as conserved protein ...
Hardin C Timothy, Rouchka Eric C
doaj   +1 more source

Bioinformatical analysis of eukaryotic shugoshins reveals meiosis-specific features of vertebrate shugoshins [PDF]

PeerJ, 2016
Background Shugoshins (SGOs) are proteins that protect cohesins located at the centromeres of sister chromatids from their early cleavage during mitosis and meiosis in plants, fungi, and animals.
Tatiana M. Grishaeva, Darya Kulichenko, Yuri F. Bogdanov   +2 more
doaj   +2 more sources

Large-scale inference and graph theoretical analysis of gene-regulatory networks in B. stubtilis

, 2006
We present the methods and results of a two-stage modeling process that generates candidate gene-regulatory networks of the bacterium B. subtilis from experimentally obtained, yet mathematically underdetermined microchip array data.
Albert, Anshuman Gupta, Barabasi, Christiansen, Christiansen, Claire Christensen, Costas D. Maranas, Csete, Dauner, Dauner, Dauner, Dauner, Dauner, D’Haeseleer, Gardner, Gavin, Giot, Guelzim, Gupta, Hartemink, Ho, Holter, Ito, Jeong, Kashtan, Latora, Latora, Lee, Li, Luscombe, Mangan, Mangan, Ma’ayan, Milo, Newman, Oltvai, Réka Albert, Sauer, Shen-Orr, Uetz, Vazquez, Yeung, Zaslaver   +42 more
core   +1 more source

Cloning of NruI and Sbo13I restriction and modification sstems in E. coli and amino acid sequence comparison of M.NruI and M.Sbo13I with other amino-methyltransferases

BMC Research Notes, 2010
Background NruI and Sbo13I are restriction enzyme isoschizomers with the same recognition sequence 5' TCG↓CGA 3' (cleavage as indicated↓). Here we report the cloning of NruI and Sbo13I restriction-modification (R-M) systems in E. coli.
Benner Jack, Fomenkov Alexey, Pedamallu Chandra, Zhu Zhenyu, Xu Shuang-yong   +4 more
doaj   +1 more source

Identification of 22 Novel Motifs of the Cell Entry Fusion Glycoprotein B of Oncolytic Herpes Simplex Viruses: Sequence Analysis and Literature Review

Frontiers in Oncology, 2020
Objective: Herpes simplex viruses (HSVs) are widely spread throughout the world, causing infections from oral, and genital mucous membrane ulcerations to severe viral encephalitis. Glycoprotein B (gB) was the first HSV envelope glycoprotein identified to
Fang Shi, Fang Shi, Fang Shi, Victoria W. Xin, Xiao-Qin Liu, Xiao-Qin Liu, Ying-Ying Wang, Ying-Ying Wang, Ying Zhang, Ying Zhang, Jun-Ting Cheng, Jun-Ting Cheng, Wen-Qi Cai, Wen-Qi Cai, Ying Xiang, Ying Xiang, Xiao-Chun Peng, Xiao-Chun Peng, Xiao-Chun Peng, Xianwang Wang, Xianwang Wang, Xianwang Wang, Hong-Wu Xin, Hong-Wu Xin, Hong-Wu Xin   +24 more
doaj   +1 more source