Results 31 to 40 of about 257,506 (253)

Bioinformatical analysis of eukaryotic shugoshins reveals meiosis-specific features of vertebrate shugoshins [PDF]

PeerJ, 2016
Background Shugoshins (SGOs) are proteins that protect cohesins located at the centromeres of sister chromatids from their early cleavage during mitosis and meiosis in plants, fungi, and animals.
Tatiana M. Grishaeva, Darya Kulichenko, Yuri F. Bogdanov   +2 more
doaj   +2 more sources

Cloning of NruI and Sbo13I restriction and modification sstems in E. coli and amino acid sequence comparison of M.NruI and M.Sbo13I with other amino-methyltransferases

BMC Research Notes, 2010
Background NruI and Sbo13I are restriction enzyme isoschizomers with the same recognition sequence 5' TCG↓CGA 3' (cleavage as indicated↓). Here we report the cloning of NruI and Sbo13I restriction-modification (R-M) systems in E. coli.
Benner Jack, Fomenkov Alexey, Pedamallu Chandra, Zhu Zhenyu, Xu Shuang-yong   +4 more
doaj   +1 more source

Characterization and identification of lysine glutarylation based on intrinsic interdependence between positions in the substrate sites

BMC Bioinformatics, 2019
Background Glutarylation, the addition of a glutaryl group (five carbons) to a lysine residue of a protein molecule, is an important post-translational modification and plays a regulatory role in a variety of physiological and biological processes.
Kai-Yao Huang, Hui-Ju Kao, Justin Bo-Kai Hsu, Shun-Long Weng, Tzong-Yi Lee   +4 more
doaj   +1 more source

Identification of 22 Novel Motifs of the Cell Entry Fusion Glycoprotein B of Oncolytic Herpes Simplex Viruses: Sequence Analysis and Literature Review

Frontiers in Oncology, 2020
Objective: Herpes simplex viruses (HSVs) are widely spread throughout the world, causing infections from oral, and genital mucous membrane ulcerations to severe viral encephalitis. Glycoprotein B (gB) was the first HSV envelope glycoprotein identified to
Fang Shi, Fang Shi, Fang Shi, Victoria W. Xin, Xiao-Qin Liu, Xiao-Qin Liu, Ying-Ying Wang, Ying-Ying Wang, Ying Zhang, Ying Zhang, Jun-Ting Cheng, Jun-Ting Cheng, Wen-Qi Cai, Wen-Qi Cai, Ying Xiang, Ying Xiang, Xiao-Chun Peng, Xiao-Chun Peng, Xiao-Chun Peng, Xianwang Wang, Xianwang Wang, Xianwang Wang, Hong-Wu Xin, Hong-Wu Xin, Hong-Wu Xin   +24 more
doaj   +1 more source

Artificial Proteins Designed from G3LEA Contribute to Enhancement of Oxidation Tolerance in E. coli in a Chaperone-like Manner

Antioxidants, 2023
G3LEA is a family of proteins that exhibit chaperone-like activity when under distinct stress. In previous research, DosH was identified as a G3LEA protein from model extremophile—Deinococcus radiodurans R1 with a crucial core HD domain consisting of ...
Jiahui Han, Shijie Jiang, Zhengfu Zhou, Min Lin, Jin Wang   +4 more
doaj   +1 more source

The L motifs of two moss pentatricopeptide repeat proteins are involved in RNA editing but predominantly not in RNA recognition.

PLoS ONE, 2020
Pentatricopeptide repeat (PPR) proteins, composed of PPR motifs repeated in tandem, are sequence-specific RNA binding proteins. Recent bioinformatic studies have shown that the combination of polar amino acids at positions 5 and last in each PPR motif ...
Takuya Matsuda, Mamoru Sugita, Mizuho Ichinose   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Molecular insights into the VIRESCENS amino acid sequence and its implication in anthocyanin production in red- and yellow-fruited cultivars of date palm

Scientific Reports, 2023
This study examined the amino acid sequence of the VIRESCENS gene (VIR), which regulates the production of anthocyanin in 12 cultivars of the date palm (Phoenix dactylifera L.), grown in Al-Madinah Al-Munawarah of the Kingdom of Saudi Arabia.
Nadia M. Alsuhaimi, Nadia S. Al-Kaff
doaj   +1 more source

Length-Dependent Transition from Extended to Folded Shapes in Short Oligomers of an Azetidine-Based α-Amino Acid: The Critical Role of NH···N H-Bonds

Molecules, 2023
Hydrogen bonds (H-bonds) are ubiquitous in peptides and proteins and are central to the stabilization of their structures. Inter-residue H-bonds between non-adjacent backbone amide NH and C=O motifs lead to the well-known secondary structures of helices,
Dayi Liu, Jean-Xavier Bardaud, Zeynab Imani, Sylvie Robin, Eric Gloaguen, Valérie Brenner, David J. Aitken, Michel Mons   +7 more
doaj   +1 more source