Results 91 to 100 of about 2,474,551 (357)

COPASAAR--a database for proteomic analysis of single amino acid repeats. [PDF]

, 2005
Background Single amino acid repeats make up a significant proportion in all of the proteomes that have currently been determined. They have been shown to be functionally and medically significant, and are associated with cancers and neuro-degenerative ...
Depledge, D.P., Dalby, A.R.
core   +1 more source

Amino acid "little Big Bang": Representing amino acid substitution matrices as dot products of Euclidian vectors

BMC Bioinformatics, 2010
Background Sequence comparisons make use of a one-letter representation for amino acids, the necessary quantitative information being supplied by the substitution matrices.
Zimmermann Karel, Gibrat Jean-François
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

ANCAC: amino acid, nucleotide, and codon analysis of COGs – a tool for sequence bias analysis in microbial orthologs

BMC Bioinformatics, 2012
Background The COG database is the most popular collection of orthologous proteins from many different completely sequenced microbial genomes. Per definition, a cluster of orthologous groups (COG) within this database exclusively contains proteins that ...
Meiler Arno, Klinger Claudia, Kaufmann Michael   +2 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Amino acid sequences of proteins from Leptospira serovar pomona

Memorias do Instituto Oswaldo Cruz, 2000
This report describes a partial amino acid sequences from three putative outer envelope proteins from Leptospira serovar pomona. In order to obtain internal fragments for protein sequencing, enzymatic and chemical digestion was performed.
Alves Selmo F, LeFebvre Rance B, Probert William   +2 more
doaj  

Coevolution-based inference of amino acid interactions underlying protein function

eLife, 2018
Protein function arises from a poorly understood pattern of energetic interactions between amino acid residues. Sequence-based strategies for deducing this pattern have been proposed, but lack of benchmark data has limited experimental verification. Here,
Victor H Salinas, Rama Ranganathan
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Complete genome sequence of Corynebacterium variabile DSM 44702 isolated from the surface of smear-ripened cheeses and insights into cheese ripening and flavor generation

, 2011
Schröder J, Maus I, Trost E, Tauch A. Complete genome sequence of Corynebacterium variabile DSM 44702 isolated from the surface of smear-ripened cheeses and insights into cheese ripening and flavor generation. BMC Genomics.
Maus Irena, Schröder Jasmin, Andreas Tauch, Tauch Andreas, Jasmin Schröder, Trost, Eva ; https://orcid.org/, Tauch, Andreas, Schröder, Jasmin, Maus, Irena, Eva Trost, Trost Eva, Irena Maus   +11 more
core   +1 more source

Comparison of the enhancer II region amino acid sequence with the reference sequence (Normal) showing amino acid substitutions and deletions.

, 2022
Comparison of the enhancer II region amino acid sequence with the reference sequence (Normal) showing amino acid substitutions and deletions.
Muhammad Nasir Khabir (11902205), Safia Bibi (3341969), Mehrunnisa Fatima Gondal (11902196), Aisha Gul (11902208), Abdul Majid (3176088), Sobia Attaullah (8697711), Majid Khan (277235), Bakht Tarin Khan (11902199), Sanaullah Khan (725797), Ayesha Khattak (11902202), Muhammad Anwar (4014383), Maryam Naseem (11902211)   +11 more
core   +1 more source