Results 81 to 90 of about 2,474,551 (357)
Rose: Generating Sequence Families
Stoye J, Evers D, Meyer F. Rose: Generating Sequence Families. Forschungsberichte.
Stoye, Jens ; https://orcid.org/ +2 more
core +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Amino acid sequence of fast-twitch skeletal muscle calsequestrin
Partial amino acid sequence analysis of rabbit fast-twitch skeletal muscle calsequestrin permitted the construction of synthetic oligonucleotides that were used as both primers and probes for the synthesis and isolation of cDNAs encoding calsequestrin ...
MacLennan, David H. +5 more
core +1 more source
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Comparative functional genomics of amino acid metabolism of lactic acid bacteria
The amino acid metabolism of lactic acid bacteria used as starters in industrial fermentations has profound effects on the quality of the fermented foods.
Pastink, M.I.
core
Amino-acid sequence for non-mutant and mutant Msx1 homeodomain used for homology modelling.
Amino-acid sequence for non-mutant and mutant Msx1 homeodomain used for homology modelling.
Vladimir J. Balcar (5728256) +9 more
core +1 more source
Vpr is an HIV-1 accessory protein that plays numerous roles during viral replication, and some of which are cell type dependent. To test the hypothesis that HIV-1 tropism extends beyond the envelope into the vpr gene, studies were performed to identify ...
Gregory C. Antell +14 more
doaj +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Amino-acid sequence alignment of LmjF.21.0725 homologs derived from various Leishmania species.
Amino-acid sequence alignment of LmjF.21.0725 homologs derived from various Leishmania species.
Eduardo Brandt Oliveira (299614) +6 more
core +1 more source

