Results 41 to 50 of about 34,511,928 (256)

Amino acid transport in plants [PDF]

, 1998
Amino acids are transported between different organs through both xylem and phloem. This redistribution of nitrogen and carbon requires the activity of amino acid transporters in the plasma membrane.
Tegeder, M., Frommer, Wolf B, Fischer, Wolf-Nicolas, Fisher, Wilfried-Edward, Krolkiewuicz, S., André, Bruno, Breitkreuz, Kevin, Krolkiewicz, Sylvia, Breitkreuz, Kevin E, Rentsch, D, Tegeder, Mechthild, Rentsch, Doris   +11 more
core   +1 more source

Cationic amino acid transport across the blood-brain barrier is mediated exclusively by system y⁺

American Journal of Physiology-Endocrinology and Metabolism, 2006
Cationic amino acid (CAA) transport is brought about by two families of proteins that are found in various tissues: Cat (CAA transporter), referred to as system y+, and Bat [broad-scope amino acid (AA) transporter], which comprises systems b0,+, B0,+, and y+L.
Robyn L, O'Kane, Juan R, Viña, Ian, Simpson, Rosa, Zaragozá, Ashwini, Mokashi, Richard A, Hawkins   +5 more
openaire   +3 more sources

Xenogeneic, extracorporeal liver perfusion in primates improves the ratio of branched-chain amino acids to aromatic amino acids (Fischer's ratio) [PDF]

, 1999
In fulminant hepatic failure (FHF), the development of hepatic encephalopathy is associated with grossly abnormal concentrations of plasma amino acids (PAA).
Puhl, G., Neuhaus, P., Schön, M. R., Hammer, C., Matthes, M., Heil, W., Lemmens, H.-P., Padval, D.   +7 more
core   +1 more source

Amino acid racemization dating: Method development using African ostrich (Struthio camelus) eggshell [PDF]

, 2013
Ostrich eggshell (OES) is ubiquitous in archaeological sites in Africa and is a favoured substrate for amino acid racemisation (AAR) geochronology, yielding consistent results and thought to approximate a closed system with respect to protein diagenesis.
Crisp, Molly Katherine
core   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Different types of potassium transport linked to carbachol and γ-aminobutyric acid actions in rat sympathetic neurons [PDF]

, 1984
Carbachol and γ-aminobutyric acid depolarize mammalian sympathetic neurons and increase the free extracellular K+-concentration. We have used double-barrelled ion-sensitive microelectrodes to determine changes of the membrane potential and of the free ...
Ballanyi, Klaus, Ten Bruggencate, Gerrit, Grafe, Peter, Reddy, M. M.   +3 more
core   +1 more source

Inhibition of endothelial cell amino acid transport System y+ by arginine analogs that inhibit nitric oxide synthase

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1997
A variety of N omega-monosubstituted L-arginine analogs are established inhibitors of nitric oxide synthase; in all cases, initial binding is competitive with the substrate L-arginine. The efficacy of such compounds in vivo will depend on their transport into the relevant nitric oxide synthase-containing cells; in fact, inhibition may actually be ...
McDonald, Kelly K, Rouhani, Riaz, Handlogten, Mary E, Block, Edward R, Griffith, Owen W, Allison, R.Donald, Kilberg, Michael S   +6 more
openaire   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Intrauterine Growth Retardation Is Associated With Reduced Activity and Expression of the Cationic Amino Acid Transport Systems y ⁺ /hCAT-1 and y ⁺ /hCAT-2B and Lower Activity of Nitric Oxide Synthase in Human Umbilical Vein Endothelial Cells [PDF]

Circulation Research, 2002
Intrauterine growth retardation (IUGR) is associated with vascular complications leading to hypoxia and abnormal fetal development. The effect of IUGR on l -arginine transport and nitric oxide (NO) synthesis was investigated in cultures of human umbilical vein endothelial cells (HUVECs).
Paola Casanello, Luis Sobrevia
openaire   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source