Results 251 to 260 of about 248,141 (296)

The Amino Acid Transport System y+L Induced in Xenopus laevis Oocytes by Human Choriocarcinoma Cell (JAR) mRNA Is Functionally Related to the Heavy Chain of the 4F2 Cell Surface Antigen

Biochemistry, 1995
Injection of mRNA isolated from human placental choriocarcinoma cells (JAR) into Xenopus laevis oocytes induced the transport of the neutral amino acid leucine as well as the transport of the cationic amino acid arginine. The induced transport of leucine was predominantly Na(+)-dependent, whereas that of arginine was Na(+)-independent.
Y J, Fei, P D, Prasad, F H, Leibach, V, Ganapathy   +3 more
openaire   +3 more sources

Cation and harmaline interactions with Na+-independent dibasic amino acid transport system y+ in human erythrocytes and in erythrocytes from a primitive vertebrate the pacific hagfish (Eptatretus stouti)

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1991
Transport systems y+, asc and ASC exhibit dual interactions with dibasic and neutral amino acids. For conventional Na(+)-dependent neutral amino acid system ASC, side chain amino and guanido groups bind to the Na+ site on the transporter. The topographically equivalent recognition site on related system asc binds harmaline (a Na(+)-site inhibitor) with
J D, Young, D A, Fincham, C M, Harvey
openaire   +3 more sources

Modulation of the Cationic Amino Acid Transport System y⁺L by Surface Potential, Ouabain and Thrombin in Human Platelets: Effects of Uremia

Nephron Experimental Nephrology, 2007
<i>Background:</i> Nitric oxide (NO), a key endogenous mediator involved in the maintenance of platelet function, is synthesized from the amino acid <i>L</i>-arginine. We have shown that <i>L</i>-arginine transport in platelets is rate-limiting for NO synthesis.
Mariana Alves de Sá Siqueira, Marcela Anjos Martins, Natália Rodrigues Pereira, Monique Bandeira Moss, Sérgio F.F. Santos, Giovanni E. Mann, Antônio C. Mendes-Ribeiro, Tatiana M.C. Brunini   +7 more
openaire   +2 more sources

Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A

Biochimica Et Biophysica Acta - Biomembranes, 2000
Takahiro Hatanaka, Mitsuru Sugawara, Puttur D Prasad   +2 more
exaly   +2 more sources

Structure and function of ATA3, a new subtype of amino acid transport system A, primarily expressed in the liver and skeletal muscle

Biochimica Et Biophysica Acta - Biomembranes, 2000
Mitsuru Sugawara, Takeo Nakanishi, You-Jun Fei   +2 more
exaly   +2 more sources

Structure, Function, and Tissue Expression Pattern of Human SN2, a Subtype of the Amino Acid Transport System N

Biochemical and Biophysical Research Communications, 2001
Takeo Nakanishi, Mitsuru Sugawara, Robert G Martindale   +2 more
exaly   +2 more sources

Involvement of transporter recruitment as well as gene expression in the substrate-induced adaptive regulation of amino acid transport system A

Biochimica Et Biophysica Acta - Biomembranes, 2001
Christy C Bridges, Mitsuru Sugawara, Takuya Fujita   +2 more
exaly   +2 more sources

Plasma membrane clustering of system y+ (CAT-1) amino acid transporter as detected by immunohistochemistry

American Journal of Physiology-Endocrinology and Metabolism, 1994
Transport of cationic amino acids in fully differentiated mammalian cells is mediated primarily by system y1+ [cationic amino acid transporter (CAT)-1 gene product]. Antibodies, prepared against synthetic peptide sequences predicted to be extracellular loops of the CAT-1 transporter protein, detected the transporter on the surface of cultured cells. In
M H, Woodard, W A, Dunn, R O, Laine, M, Malandro, R, McMahon, O, Simell, E R, Block, M S, Kilberg   +7 more
openaire   +2 more sources

Identification of the Cationic Amino Acid Transporter (System y⁺) of the Rat Blood‐Brain Barrier

Journal of Neurochemistry, 1993
Abstract: Cationic amino acids are transported from blood into brain by a saturable carrier at the blood‐brain barrier (BBB). The transport properties of this carrier were examined in the rat using an in situ brain perfusion technique. Influx into brain via this system was found to be sodium independent and followed Michaelis‐Men‐ten kinetics with ...
J, Stoll, K C, Wadhwani, Q R, Smith
openaire   +2 more sources

Osmotic Regulation of ATA2 mRNA Expression and Amino Acid Transport System A Activity

Biochemical and Biophysical Research Communications, 2001
Roberta R Alfieri, Pier Giorgio Petronini, Mara A Bonelli   +2 more
exaly   +2 more sources