Results 261 to 270 of about 248,141 (296)
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Pflügers Archiv, 2000
We test the hypothesis that lysinuric protein intolerance (LPI), a rare autosomal recessive defect of cationic amino acid transport, results from the absence of the recently described y+L amino acid transporter. We compare fluxes of lysine (1 microM) into erythrocytes of normal subjects with those of patients homozygous for the LPI mutation.
BOYD CA +4 more
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We test the hypothesis that lysinuric protein intolerance (LPI), a rare autosomal recessive defect of cationic amino acid transport, results from the absence of the recently described y+L amino acid transporter. We compare fluxes of lysine (1 microM) into erythrocytes of normal subjects with those of patients homozygous for the LPI mutation.
BOYD CA +4 more
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The adaptive regulation of amino acid transport system A is associated to changes in ATA2 expression
FEBS Letters, 2001Roberto Sala +2 more
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Archives of Biochemistry and Biophysics, 1985
Three major pathways mediate amino acid transport into mammalian cells: the A-system and the ASC-system, which require a sodium gradient across the plasma membrane, and the L-system, which has no requirement for a sodium gradient. We have found that the lymphocytes from patients with B-cell chronic lymphocytic leukemia (CLL) have a marked reduction in ...
G B, Segel, A M, Tometsko, M A, Lichtman
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Three major pathways mediate amino acid transport into mammalian cells: the A-system and the ASC-system, which require a sodium gradient across the plasma membrane, and the L-system, which has no requirement for a sodium gradient. We have found that the lymphocytes from patients with B-cell chronic lymphocytic leukemia (CLL) have a marked reduction in ...
G B, Segel, A M, Tometsko, M A, Lichtman
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Cationic amino acid transport across the blood-brain barrier is mediated exclusively by system y+
American Journal of Physiology - Endocrinology and Metabolism, 2006 Cationic amino acid (CAA) transport is brought about by two families of proteins that are found in various tissues: Cat (CAA transporter), referred to as system y+, and Bat [broad-scope amino acid (AA) transporter], which comprises systems b0,+, B0 ...
JOSÉ Vina, Richard A Hawkins
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Biochimica et Biophysica Acta (BBA) - Biomembranes, 1987
The transport of glycine and L-lysine into murine P388 leukemia cells has been examined. Glycine transport appears to be shared by both systems A and ASC in P388 cells. Glycine transport is Na+-dependent and is effectively blocked by alpha-(methylamino)isobutyric acid, threonine and alanine but only a marginal reduction in transport is seen with 100 ...
P, Lazarus, L C, Panasci
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The transport of glycine and L-lysine into murine P388 leukemia cells has been examined. Glycine transport appears to be shared by both systems A and ASC in P388 cells. Glycine transport is Na+-dependent and is effectively blocked by alpha-(methylamino)isobutyric acid, threonine and alanine but only a marginal reduction in transport is seen with 100 ...
P, Lazarus, L C, Panasci
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Journal of Cellular Physiology, 1993
AbstractThe uptake of L‐leucine and L‐lysine into vascular smooth muscle cells cultured from the aortas of rats has been investigated. Both amino acids are taken up by saturable systems that are independent of the presence of a ·Na+ gradient and can be stimulated in trans by neutral bulky amino acids for leucine and cationic amino acids for lysine ...
B C, Low, I K, Ross, M R, Grigor
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AbstractThe uptake of L‐leucine and L‐lysine into vascular smooth muscle cells cultured from the aortas of rats has been investigated. Both amino acids are taken up by saturable systems that are independent of the presence of a ·Na+ gradient and can be stimulated in trans by neutral bulky amino acids for leucine and cationic amino acids for lysine ...
B C, Low, I K, Ross, M R, Grigor
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Biochemistry, 1993
Two-microelectrode voltage clamp was used to measure membrane currents resulting from flux of cationic amino acids in Xenopus oocytes expressing the cloned dual-function ecotropic murine leukemia virus receptor/system y+ transporter. At membrane potentials ranging from +20 mV to -120 mV, arginine influx obeyed Michaelis-Menten kinetics.
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Two-microelectrode voltage clamp was used to measure membrane currents resulting from flux of cationic amino acids in Xenopus oocytes expressing the cloned dual-function ecotropic murine leukemia virus receptor/system y+ transporter. At membrane potentials ranging from +20 mV to -120 mV, arginine influx obeyed Michaelis-Menten kinetics.
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Journal of Membrane Biology, 2001
The functional properties of the transport of lysine across the chicken erythrocyte membrane were investigated. The animal population studied (male Leghorn chickens, 6-14 weeks old) was found to consist of two groups presenting either low (LT, 19 individuals) or high transport rates (HT, 20 individuals).
M, Vargas, R, Devés
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The functional properties of the transport of lysine across the chicken erythrocyte membrane were investigated. The animal population studied (male Leghorn chickens, 6-14 weeks old) was found to consist of two groups presenting either low (LT, 19 individuals) or high transport rates (HT, 20 individuals).
M, Vargas, R, Devés
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The FASEB Journal, 2005
ABSTRACT The transport of arginine has been characterized in human airway Calu‐3 cells. As assessed with RT‐PCR, Calu‐3 cells express the genes for several transporters, such as the system y + ‐related SLC7A1, SLC7A2 , and
ROTOLI, Bianca Maria +4 more
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ABSTRACT The transport of arginine has been characterized in human airway Calu‐3 cells. As assessed with RT‐PCR, Calu‐3 cells express the genes for several transporters, such as the system y + ‐related SLC7A1, SLC7A2 , and
ROTOLI, Bianca Maria +4 more
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