Results 151 to 160 of about 174 (173)
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System y + L-like Activities Account for High and Low Amino-Acid Transport Phenotypes in Chicken Erythrocytes

Journal of Membrane Biology, 2001
The functional properties of the transport of lysine across the chicken erythrocyte membrane were investigated. The animal population studied (male Leghorn chickens, 6-14 weeks old) was found to consist of two groups presenting either low (LT, 19 individuals) or high transport rates (HT, 20 individuals).
M, Vargas, R, Devés
openaire   +2 more sources

The transport of cationic amino acids in human airway cells: expression of system y + L activity and transepithelial delivery of NOS inhibitors

The FASEB Journal, 2005
ABSTRACT The transport of arginine has been characterized in human airway Calu‐3 cells. As assessed with RT‐PCR, Calu‐3 cells express the genes for several transporters, such as the system y + ‐related SLC7A1, SLC7A2 , and
ROTOLI, Bianca Maria   +4 more
openaire   +4 more sources

Activation of cationic amino acid transport through system y+ correlates with expression of the T-cell early antigen gene in human lymphocytes

Pfl�gers Archiv European Journal of Physiology, 1992
Lysine influx (2 microM) into activated human B and T lymphocytes through transport systems y+ and y+L was measured. In activated T cells very substantial activation of system y+ was detected; system y+L was also activated in these cells but with a slower time course and to a smaller extent.
C A, Boyd, D H, Crawford
openaire   +2 more sources

Cation and harmaline interactions with Na+-independent dibasic amino acid transport system y+ in human erythrocytes and in erythrocytes from a primitive vertebrate the pacific hagfish (Eptatretus stouti)

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1991
Transport systems y+, asc and ASC exhibit dual interactions with dibasic and neutral amino acids. For conventional Na(+)-dependent neutral amino acid system ASC, side chain amino and guanido groups bind to the Na+ site on the transporter. The topographically equivalent recognition site on related system asc binds harmaline (a Na(+)-site inhibitor) with
J D, Young, D A, Fincham, C M, Harvey
openaire   +2 more sources

The Amino Acid Transport System y+L Induced in Xenopus laevis Oocytes by Human Choriocarcinoma Cell (JAR) mRNA Is Functionally Related to the Heavy Chain of the 4F2 Cell Surface Antigen

Biochemistry, 1995
Injection of mRNA isolated from human placental choriocarcinoma cells (JAR) into Xenopus laevis oocytes induced the transport of the neutral amino acid leucine as well as the transport of the cationic amino acid arginine. The induced transport of leucine was predominantly Na(+)-dependent, whereas that of arginine was Na(+)-independent.
Y J, Fei   +3 more
openaire   +2 more sources

Modulation of the Cationic Amino Acid Transport System y<sup>+</sup>L by Surface Potential, Ouabain and Thrombin in Human Platelets: Effects of Uremia

Nephron Experimental Nephrology, 2007
<i>Background:</i> Nitric oxide (NO), a key endogenous mediator involved in the maintenance of platelet function, is synthesized from the amino acid <i>L</i>-arginine. We have shown that <i>L</i>-arginine transport in platelets is rate-limiting for NO synthesis.
Mariana Alves de Sá Siqueira   +7 more
openaire   +1 more source

Modulation of the cationic amino acid transport system y+L by surface potential, ouabain and thrombin in human platelets: effects of uremia.

Nephron. Experimental nephrology, 2008
Nitric oxide (NO), a key endogenous mediator involved in the maintenance of platelet function, is synthesized from the amino acid L-arginine. We have shown that L-arginine transport in platelets is rate-limiting for NO synthesis. A disturbance in the L-arginine-NO pathway in platelets was previously described in chronic renal failure (CRF) patients ...
Siqueira, M A D   +7 more
openaire   +2 more sources

Amino acid metabolism, transport and signalling in the liver revisited

Biochemical Pharmacology, 2022
Stefan Broer   +2 more
exaly  

Primary structure, functional characteristics and tissue expression pattern of human ATA2, a subtype of amino acid transport system A

Biochimica Et Biophysica Acta - Biomembranes, 2000
Mitsuru Sugawara   +2 more
exaly  

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