Results 221 to 230 of about 200,555 (262)
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Journal of Membrane Biology, 1999
A reevaluation of the specificity of system y+, the classical transporter for cationic amino acids is presented. System y+ has been defined as a transporter for cationic amino acids that binds neutral amino acids with lower affinity in the presence of Na+.
A M, Rojas, R, Devés
exaly +3 more sources
A reevaluation of the specificity of system y+, the classical transporter for cationic amino acids is presented. System y+ has been defined as a transporter for cationic amino acids that binds neutral amino acids with lower affinity in the presence of Na+.
A M, Rojas, R, Devés
exaly +3 more sources
Placental amino acid uptake. III. Transport systems for neutral amino acids
American Journal of Physiology-Legacy Content, 1976The human placenta is known to concentrate nearly all amino acids intracellularly for transfer to the fetus. To clarify the mechanism and regulation of this process we have determined the specificity of the principal placental transport systems for neutral amino acids.
R H, Enders +3 more
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Specificity of the transport system for neutral amino acids in the hamster intestine
American Journal of Physiology-Legacy Content, 1962The specificity of the active transport system for neutral amino acids has been studied with everted sacs of hamster intestine. Amino acids with modifications or replacements of the carboxyl, amino, or α-hydrogen groups were poorly transported and were poor inhibitors of the transport of other l-amino acids.
E C, LIN, H, HAGIHIRA, T H, WILSON
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Neutral amino acid transport systems of microvillous membrane of human placenta
American Journal of Physiology-Cell Physiology, 1988Placental transport produces concentrations of amino acids in fetal blood greater than those of maternal blood. Competitive inhibition studies of zwitterionic amino acid transport in isolated vesicles from the microvillous (maternal facing) plasma membranes of syncytiotrophoblast defined three transport systems: 1) a sodium-dependent system that ...
L W, Johnson, C H, Smith
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Modulation of transport systems for neutral and anionic amino acids in mesenchymal cells
Biochemical Society Transactions, 1996Introduction The concerted operation of several amino acidtransport systems ensures the optimal composition of the intracellular compartment as well as inter-organ amino acid flow [ l ] . The operation of these transport systems is linked through substrates accumulated by active transport systems (such as Systems A and X,;;) and then exchanged with ...
DALL'ASTA, Valeria +9 more
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Experimental Cell Research, 1987
Transport of alpha-aminoisobutyric acid (AIB) in the clonal, osteoblastic-like cell line, ROS 17/2, was characterized. AIB transport was time-, temperature- and Na+-dependent. Both ouabain and monensin inhibited AIB transport in these cells. AIB uptake followed Michaelis-Menten kinetics with an apparent Km = 0.57 mM and a Vmax = 4.07 nmol/30 min/plate.
B J, Baum, A, Shteyer
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Transport of alpha-aminoisobutyric acid (AIB) in the clonal, osteoblastic-like cell line, ROS 17/2, was characterized. AIB transport was time-, temperature- and Na+-dependent. Both ouabain and monensin inhibited AIB transport in these cells. AIB uptake followed Michaelis-Menten kinetics with an apparent Km = 0.57 mM and a Vmax = 4.07 nmol/30 min/plate.
B J, Baum, A, Shteyer
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Molecular Identification of Astroglial Neutral Amino Acid Transport Systems
Developmental Neuroscience, 1996Astrocytes, like other mammalian cells, possess several different amino acid transport systems with overlapping substrate specificity. They are involved in nutrition of the astrocyte itself and the metabolic traffic between astrocytes and neurons. Recent advances in molecular cloning techniques led to the identification of several amino acid transport ...
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