AexB is an aromatic amino acid exporter that functions as a metabolic safety valve [PDF]
mBioAromatic amino acids—tryptophan, tyrosine, phenylalanine, and histidine—are essential for bacterial growth and are among the most energetically expensive metabolites to synthesize.
Blake A. Everett, Arthur Prindle
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Quantitative 1H Nuclear Magnetic Resonance (qNMR) of Aromatic Amino Acids for Protein Quantification
Methods and Protocols, 2023 Hydrolysis of protein samples into amino acids facilitates the use of NMR spectroscopy for protein and peptide quantification. Different conditions have been tested for quantifying aromatic amino acids and proteins.
Teodor Tchipilov +2 more
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Towards SERS-based multiplexed monitoring of protease activity using non-natural aromatic amino acids [PDF]
EPJ Web of Conferences, 2020 Surface Enhanced Raman Spectroscopy (SERS) allows sensitive and selective detection of protease activity by monitoring the cleavage of specific peptide substrates. Furthermore, it offers the possibility for multiplexing, during which the activity of two (
Turk Nina +4 more
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Concise construction of β-branched aromatic D-amino acids via transaminase-catalyzed dynamic kinetic resolution [PDF]
Nature CommunicationsThe synthesis of non-canonical amino acids (ncAAs) has recently made tremendous progress in the field of biocatalysis, with enzymes such as transaminases, dehydrogenases, and ammonia lyases being used.
Zhenling Liu +8 more
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The Biotransformation of Aromatic Amino Acids by Phoma macrostoma [PDF]
Natural Product Communications, 2010 A search for natural products produced in fermentation cultures of a strain of Phoma macrostoma led to the identification of tyrosol as the major metabolite produced by this organism.
Yevgeniya Tyagunova, John L. Sorensen
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Aromatic amino acid activation of signaling pathways in bone marrow mesenchymal stem cells depends on oxygen tension. [PDF]
PLoS ONE, 2014 The physiologic oxygen pressures inside the bone marrow environment are much lower than what is present in the peripheral circulation, ranging from 1-7%, compared to values as high as 10-13% in the arteries, lungs and liver.
Mona El Refaey +10 more
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Solubility Parameters of Amino Acids on Liquid–Liquid Phase Separation and Aggregation of Proteins
Frontiers in Cell and Developmental Biology, 2021 The solution properties of amino acids determine the folding, aggregation, and liquid–liquid phase separation (LLPS) behaviors of proteins. Various indices of amino acids, such as solubility, hydropathy, and conformational parameter, describe the ...
Akira Nomoto +2 more
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Biomolecules, 2021 Peptide drugs, especially food-derived peptides, have a variety of functional activities including antiviral and may also have a therapeutic effect on COVID-19.
Ai-Min Shi +3 more
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Editorial: Aromatic Amino Acid Metabolism [PDF]
Frontiers in Molecular Biosciences, 2019 National Natural Science Foundation of ChinaNational Natural Science Foundation of China [31860702]
Han, Qian +2 more
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Synthesis of potentially bioactive PABA-related N-(aminoalkyl)lactamic amino acids and esters via selective SNAr reactions [PDF]
, 2015 Potentially bioactive N-(aminoalkyl)lactamic amino acids and esters were synthesized in satisfactory to good yields by SNAr reactions of aromatic acids with N-(3-aminopropyl)lactams followed by esterification with tertiary amino alcohols.
Gonzalez, ERP +6 more
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