Results 181 to 190 of about 68,125 (243)

CRISPR/Cas9‐Based Vanadium MXene‐Free Radical Spatiotemporally Controlled Nanoreactor for Photothermal‐Induced Multi‐Effect Synergistic Antitumor Therapy

Advanced Science, EarlyView.
In this study, a MXene‐based V4C3 nanoplatform, VARH, was constructed, which achieved a photothermal conversion efficiency of 44.21% in the NIR‐II window. This platform integrated photothermal therapy, chemodynamic therapy, and thermodynamic therapy with CRISPR/Cas9‐mediated heat shock protein 90 knock‐out technology.
Zi‐Jian Huang, Feng‐Ming Li, Yi‐Fan Tu, Ke‐Ke Feng, Cheng‐Lei Li, Shi‐Cheng Tian, Yong‐Shan Hu, Jing‐Wei Shao, Zhen‐Hua Liu   +8 more
wiley   +1 more source

Interactive effects of dietary protein and fiber levels on total tract and apparent ileal nutrient digestibility, microbiota profiling, and fermentation products in pigs fed a blend of branched-chain volatile fatty acids. [PDF]

Front Vet Sci
Benavides-Infante AP, Fresno-Rueda AM, Rodrigues LA, Socha MT, Fernandes T, St-Pierre B, Perez-Palencia JY, Levesque CL.   +7 more
europepmc   +1 more source

Systematic Engineering of Proteases in Saccharopolyspora Spinosa Reveals Synergistic Enhancement of Spinosad Biosynthesis via Substrate Flux Optimization

Advanced Science, EarlyView.
ARTP mutagenesis yielded Saccharopolyspora spinosa mutant D184 with improved extracellular nitrogen utilization. An integrated workflow of protease genetic manipulation, multi‐omics, and rational synergy design pinpointed a pepP‐clpP‐htpX synergistic triangular combination.
Duo Jin, Wangqiong Chen, Danlu Yang, Qing Liu, Baolong Bai, Zirui Dai, Xirong Liu, Zirong Zhu, Jie Rang, Liqiu Xia   +9 more
wiley   +1 more source

A Colorimetric Multimetabolite Assay for Quantitative Measurement of Keto Acids in Urine for At-Home Monitoring of Metabolic Disorders. [PDF]

J Anal Methods Chem
Bhattacharyya D, Kropielnicki A, Lee BL, Khaniani Y, LeVatte MA, Wishart DS.   +5 more
europepmc   +1 more source

Review: Insight on Porous Carbon Positive Electrode for Sodium‐Ion Capacitors: Interplay Between Synthesis, Properties, and Performance

Advanced Science, EarlyView.
Sodium ion capacitor (SIC) is currently constrained by the low discharge capacity of commercial activated carbon as positive electrode material. This review provides a holistic summary of research efforts on alternative porous carbon materials for SIC. Image created by the authors with www.biorender.com.
Ademola Adeniji, Adrian Beda, Camélia Matei Ghimbeu   +2 more
wiley   +1 more source

Association between dietary amino acids ratio with metabolic profile and C-Peptide levels among overweight individuals. [PDF]

BMC Endocr Disord
Jasim SA, Oghenemaro EF, Merza MY, Baldaniya L, Ganesan S, Suliman M, Aminov Z, Nagarwal A, Kadhim AJ, Kadhim M.   +9 more
europepmc   +1 more source

Sustainable Phosphorylated Cellulose Nanocrystals: A Dual‐Affinity Platform for High‐Efficiency Enrichment of Intact Glycopeptides and Phosphopeptides

Advanced Science, EarlyView.
AAA ABSTRACT Protein glycosylation and phosphorylation are critical post‐translational modifications (PTMs) governing nearly all cellular functions, yet their analysis remains challenging due to reliance on costly and unsustainable enrichment materials.
Jiaying Li, Wuming Fan, Xuyang Yue, Dongdong Wang, Xiangyu Tang, Zhuo Zhang, Yonggui Wang, Yanjun Xie, Mingliang Ye, Hongqiang Qin   +9 more
wiley   +1 more source

A Drought-Activated Bacterial Symbiont Enhances Legume Resilience Through Coordinated Amino Acid Metabolism. [PDF]

Microorganisms
Nishu SD, No JH, Wee GN, Lee TK.
europepmc   +1 more source

Peroxidase‐Mimicking Nanozymes for Rapid Detection of Infectious Diseases

Advanced Science, EarlyView.
Peroxidase‐mimicking nanozymes (PMNs) have emerged as robust and versatile materials for rapid infectious disease diagnostics. This review highlights the rational design and controlled synthesis of PMNs, summarizes key biomarkers relevant to infectious diseases, examines their integration into diverse rapid detection platforms, and highlights ...
Shikuan Shao, Victor Fernandez‐Gonzalez, Xiaochuan Wang, Blake Pylipow, Claudia Herrera, Xiaohu Xia   +5 more
wiley   +1 more source

Contrasting effects of glutamate and branched-chain amino acid metabolism on acid tolerance in a <i>Castellaniella</i> isolate from acidic groundwater. [PDF]

Appl Environ Microbiol
Goff JL, Durrence KL, Thorgersen MP, Trotter VV, Chen Y, Kosina SM, Wang ALW, Poole FL, Northen TR, Petzold CJ, Deutschbauer AM, Adams MWW.   +11 more
europepmc   +1 more source