Results 201 to 210 of about 70,778 (262)

Downsizing the Histone H3–H4 Quaternary Structure Into Foldamer Mimetics Yields High‐Affinity and Cell‐Permeable Ligands of ASF1

Angewandte Chemie, EarlyView.
We present a foldamer strategy to downsize the histone H3‐H4 quaternary structure into high‐affinity, medium‐sized binders (∼2 kDa) for the histone chaperone ASF1. Our peptide‐oligourea chimeras, designed through structure‐guided optimization and foldamer chemistry, recapitulate the natural H3‐H4 dimer binding mode while demonstrating plasma stability ...
Bo Li, Marie E. Perrin, Emma Maillard, Arthur Vitard, Gwenaëlle Moal, Johanne Mbianda, Christophe André, Magda Teixeira Nunes, Marie Vandamme, Guillaume Pinna, Céline Douat, Emmanuelle Thinon, Raphaël Guerois, Pierre Legrand, Gilles Guichard, Francoise Ochsenbein   +15 more
wiley   +1 more source

Branched-chain amino acid specialization drove diversification within Calditenuaceae (Caldarchaeia) and enables their cultivation. [PDF]

Nat Commun
Lai D, Mosier D, Palmer M, Mayali X, Johnston J, Saldivar W, Covington JK, Jiao JY, Murali R, Seymour CO, Liu L, Hua ZS, Li WJ, Weber PK, Pett-Ridge J, Colman DR, Boyd ES, Nunoura T, Dodsworth JA, Hedlund BP.   +19 more
europepmc   +1 more source

From gut microbiota metabolism to microvascular injury: Exploring the role and mechanisms of gut microbiota in obesity-induced coronary microcirculation dysfunction. [PDF]

Virulence
Liu Y, Wang Y, Teng H, Nie W, Qiao X, Shen Y, Wang Z, Yao X.   +7 more
europepmc   +1 more source

Nutritional strategies to mitigate sub-clinical coccidiosis in Eimeria-challenged broilers. [PDF]

Poult Sci
Akter N, Dao TH, Jahan AA, Kumar A, Bedford M, Crowley TM, Moss AF.   +6 more
europepmc   +1 more source

Effects of <i>Allium mongolicum</i> Essential Oil on Meat Quality and Flavor-Related Free Amino Acids in Finishing Lambs. [PDF]

Animals (Basel)
Erdene K, Wang X, Zhao Y, Cao Q, Zheng Y, Ao C, Bai C.   +6 more
europepmc   +1 more source

Metabolites in Early-Mid Pregnancy Mediate the Association Between Prepregnancy Body Mass Index and Risk of Gestational Diabetes Mellitus. [PDF]

J Diabetes Res
Wang S, Zheng Y, Luo M, Chen W, Guo J, Jiang R, Yu X.   +6 more
europepmc   +1 more source

Stress-induced iron-sulfur cluster damage as a conserved trigger of the bacterial stringent response. [PDF]

Nat Commun
Michaud E, Ricci L, Lallement C, Barquist L, Cattoir V, Michaux C, Hallez R, Ronneau S.   +7 more
europepmc   +1 more source

Inverse stable isotopic labeling for natural product characterization and discovery.

Nat Prod Rep
Robes JMD, Puri AW.
europepmc   +1 more source