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Research progress on branched-chain amino acid aminotransferases
Frontiers in Genetics, 2023 Branched-chain amino acid aminotransferases, widely present in natural organisms, catalyze bidirectional amino transfer between branched-chain amino acids and branched-chain α-ketoacids in cells.
Can Chen +3 more
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Branched Chain Amino Acids [PDF]
Annual Review of Physiology, 2019 Branched chain amino acids (BCAAs) are building blocks for all life-forms. We review here the fundamentals of BCAA metabolism in mammalian physiology. Decades of studies have elicited a deep understanding of biochemical reactions involved in BCAA catabolism.
Danielle Murashige +2 more
exaly +3 more sources
Codon-specific ribosome stalling reshapes translational dynamics during branched-chain amino acid starvation [PDF]
Genome BiologyBackground Cells regulate protein synthesis in response to fluctuating nutrient availability through mechanisms that affect both translation initiation and elongation.
Lina Worpenberg +2 more
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Branched-chain amino acid metabolism supports Roseobacteraceae positive interactions in marine biofilms [PDF]
Applied and Environmental MicrobiologyInterspecies interactions are key factors affecting the stability of microbial communities. However, microbial interactions in marine biofilms, which constitute up to 80% of the microbial biomass in certain marine environments, are not well understood ...
Han Cui +6 more
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Branched-chain amino acid catabolism promotes M2 macrophage polarization [PDF]
Frontiers in ImmunologyIntroductionDuring an immune response, macrophages undergo systematic metabolic rewiring tailored to support their functions. Branched-chain amino acid (BCAA) metabolism has been reported to modulate macrophage function; however, its role in macrophage ...
Manxi Lu +12 more
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Branched‐chain amino acids [PDF]
Journal of Gastroenterology and Hepatology, 2000 AbstractThe branched‐chain amino acids (BCAA), isoleucine, leucine and valine, are unique in that they are principally metabolized extrahepatically in the skeletal muscle. This observation led to the investigation of these nutrients in a number of clinical scenarios.
C, Platell +3 more
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The biological functions and metabolic pathways of valine in swine
Journal of Animal Science and Biotechnology, 2023 Valine is an essential amino acid and a type of branched-chain amino acid. Due to the involvement of branched-chain amino acids in various metabolic pathways, there has been a surge of interests in valine nutrition and its role in animal physiology.
Chuni Wang +6 more
doaj +1 more source
Frontiers in Microbiology, 2018 Isoleucine 2-epimerase (ILEP) is a novel branched-chain amino acid racemase isolated from Lactobacillus buchneri. In this study, we examined production of free d-branched-chain amino acids such as d-valine, d-leucine, and d-allo-isoleucine, using lactic ...
Yuta Mutaguchi, Kano Kasuga, Ikuo Kojima
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Frontiers in Microbiology, 2018 Micrococcus luteus naturally produces alkenes, unsaturated aliphatic hydrocarbons, and represents a promising host to produce hydrocarbons as constituents of biofuels and lubricants.
Maximilian J. Surger +4 more
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Aberrant branched-chain amino acid catabolism in cardiovascular diseases
Frontiers in Cardiovascular Medicine, 2022 Globally, cardiovascular diseases are the leading cause of death. Research has focused on the metabolism of carbohydrates, fatty acids, and amino acids to improve the prognosis of cardiovascular diseases.
Yixiao Xiong +5 more
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