Results 1 to 10 of about 70,513 (117)

Research progress on branched-chain amino acid aminotransferases

Frontiers in Genetics, 2023
Branched-chain amino acid aminotransferases, widely present in natural organisms, catalyze bidirectional amino transfer between branched-chain amino acids and branched-chain α-ketoacids in cells.
Can Chen, Hassan Naveed, Hassan Naveed, Keping Chen   +3 more
doaj   +3 more sources

Genetic and metabolic drivers of membrane remodeling in Clostridium thermocellum under alcohol stress [PDF]

mSystems
Clostridium thermocellum is a leading candidate for consolidated bioprocessing of lignocellulosic biomass into biofuels due to its native cellulolytic capabilities. Beyond ethanol, C.
Eashant Thusoo, Tyler Jacobson, Bishal D. Sharma, Isabella M. Colón, Lee R. Lynd, Daniel G. Olson, Daniel Amador-Noguez   +6 more
doaj   +2 more sources

Circulating branch chain amino acids and improvement in liver fat content in response to exercise interventions in NAFLD

Scientific Reports, 2021
Nonalcoholic fatty liver disease is likely to be associated with increased circulating branched-chain amino acids. We investigated the relationship between changes in branched-chain amino acids levels in the serum and improvement in liver fat content ...
Xiulin Shi, Hongyan Yin, Jia Li, Caoxin Huang, Yinling Chen, Zheng Chen, Wei Liu, Weijuan Su, Yiping Zhang, Mingzhu Lin, Yan Zhao, Xuejun Li   +11 more
doaj   +1 more source

Branched chain amino acids metabolism in heart failure

Frontiers in Nutrition, 2023
As a terminal stage of various cardiovascular diseases, heart failure is of great concern due to its high mortality rate and limited treatment options.
Chenshan Gao, Lei Hou, Lei Hou
doaj   +1 more source

The biological functions and metabolic pathways of valine in swine

Journal of Animal Science and Biotechnology, 2023
Valine is an essential amino acid and a type of branched-chain amino acid. Due to the involvement of branched-chain amino acids in various metabolic pathways, there has been a surge of interests in valine nutrition and its role in animal physiology.
Chuni Wang, Yao Peng, Yiru Zhang, Juan Xu, Sheng Jiang, Leli Wang, Yulong Yin   +6 more
doaj   +1 more source

Production of d-Branched-Chain Amino Acids by Lactic Acid Bacteria Carrying Homologs to Isoleucine 2-Epimerase of Lactobacillus buchneri

Frontiers in Microbiology, 2018
Isoleucine 2-epimerase (ILEP) is a novel branched-chain amino acid racemase isolated from Lactobacillus buchneri. In this study, we examined production of free d-branched-chain amino acids such as d-valine, d-leucine, and d-allo-isoleucine, using lactic ...
Yuta Mutaguchi, Kano Kasuga, Ikuo Kojima
doaj   +1 more source

Amino acid accumulation limits the overexpression of proteins in Lactococcus lactis. [PDF]

PLoS ONE, 2010
BACKGROUND: Understanding the biogenesis pathways for the functional expression of recombinant proteins, in particular membrane proteins and complex multidomain assemblies, is a fundamental issue in cell biology and of high importance for future progress
Ravi K R Marreddy, Eric R Geertsma, Hjalmar P Permentier, Joao P C Pinto, Jan Kok, Bert Poolman   +5 more
doaj   +1 more source

Immunometabolism – The Role of Branched-Chain Amino Acids

Frontiers in Immunology, 2022
Immunometabolism has been the focus of extensive research over the last years, especially in terms of augmenting anti-tumor immune responses. Regulatory T cells (Tregs) are a subset of CD4+ T cells, which have been known for their immunosuppressive roles
Berkay Yahsi, Gurcan Gunaydin
doaj   +1 more source

Dataset describing the amino acid catabolism of Thermoanaerobacter strain AK85: The influence of culture conditions on end product formation

Data in Brief, 2019
The dataset describes the catabolism of the 20 proteogenics amino acids and their end products by Thermoanaerobacter strain AK85 under different electron scavenging conditions with an emphasis on the branched-chain amino acids as reported in Scully and ...
Sean Michael Scully, Johann Orlygsson
doaj   +1 more source

BCKDK of BCAA Catabolism Cross-talking With the MAPK Pathway Promotes Tumorigenesis of Colorectal Cancer

EBioMedicine, 2017
Branched-chain amino acids catabolism plays an important role in human cancers. Colorectal cancer is the third most commonly diagnosed cancer in males and the second in females, and the new global incidence is over 1.2 million cases. The branched-chain α-
Peipei Xue, Fanfan Zeng, Qiuhong Duan, Juanjuan Xiao, Lin Liu, Ping Yuan, Linni Fan, Huimin Sun, Olesya S. Malyarenko, Hui Lu, Ruijuan Xiu, Shaoqing Liu, Chen Shao, Jianmin Zhang, Wei Yan, Zhe Wang, Jianyong Zheng, Feng Zhu   +17 more
doaj   +1 more source