Results 11 to 20 of about 70,778 (262)

Branched‐chain amino acids [PDF]

Journal of Gastroenterology and Hepatology, 2000
AbstractThe branched‐chain amino acids (BCAA), isoleucine, leucine and valine, are unique in that they are principally metabolized extrahepatically in the skeletal muscle. This observation led to the investigation of these nutrients in a number of clinical scenarios.
C, Platell, S E, Kong, R, McCauley, J C, Hall   +3 more
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Branch chain amino acid and melanogenesis [PDF]

Immunopharmacology and Immunotoxicology, 2011
Sir, the recent publication on branch chain amino acid (BCAA) and melanogenesis is very interesting. Cha et al. report that “a complex of BCAAs inhibited melanin production without changes in intercellular tyrosinase activity,” and they propose further that “the complex of BCAAs may be used in the development of safe potential depigmenting agents ...
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Branched-Chain Amino Acids and Immunity , [PDF]

The Journal of Nutrition, 2006
Although there has been great interest in the effects of amino acids on immune function, little is known about the impact of changes in BCAA availability on the ability of the immune system to function. Human immune cells incorporate BCAA into proteins and are able to oxidize BCAA.
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Branched-Chain Amino Acids and Branched-Chain Keto Acids in Hyperammonemic States: Metabolism and as Supplements

Metabolites, 2020
In hyperammonemic states, such as liver cirrhosis, urea cycle disorders, and strenuous exercise, the catabolism of branched-chain amino acids (BCAAs; leucine, isoleucine, and valine) is activated and BCAA concentrations decrease.
Milan Holeček
doaj   +1 more source

Plasma Amino Acid Concentrations Predict Mortality in Patients with End-Stage Liver Disease. [PDF]

PLoS ONE, 2016
The liver plays a key role in amino acid metabolism. In former studies, a ratio between branched-chain and aromatic amino acids (Fischer's ratio) revealed associations with hepatic encephalopathy.
Benedict Kinny-Köster, Michael Bartels, Susen Becker, Markus Scholz, Joachim Thiery, Uta Ceglarek, Thorsten Kaiser   +6 more
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Disorders of branched chain amino acid metabolism

Translational Science of Rare Diseases, 2016
The three essential branched-chain amino acids (BCAAs), leucine, isoleucine and valine, share the first enzymatic steps in their metabolic pathways, including a reversible transamination followed by an irreversible oxidative decarboxylation to coenzyme-A derivatives.
Manoli, I., Venditti, C.P.
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The Effect of Amino Acids on Production of SCFA and bCFA by Members of the Porcine Colonic Microbiota

Microorganisms, 2022
Functional amino acids supplementation to farm animals is considered to not only be beneficial by regulating intestinal barrier, oxidative stress, and immunity, but potentially also by impacting the gut microbiota.
Pieter Van den Abbeele, Jonas Ghyselinck, Massimo Marzorati, Anna-Maria Koch, William Lambert, Joris Michiels, Tristan Chalvon-Demersay   +6 more
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Genome-wide association studies reveal the genetic basis of amino acid content variation in tea plants

Journal of Integrative Agriculture, 2023
Tea is one of the most popular non-alcoholic beverages in the world, and free amino acids, especially theanine, make a major contribution to the umami taste of tea.
Ya-fei GUO, Dai-li LI, Hai-ji QIU, Xiao-liang ZHANG, Lin LIU, Jing-jing ZHAO, De-yuan JIANG   +6 more
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Setting the Stage for Branched-Chain Amino Acids Use in Neurological Pathologies: Does a Single Oral Dose Provide Hours of Elevated Systemic Levels?

Diseases
Background: Recent studies have demonstrated that branched-chain amino acids are neuroprotective and neurorestorative. Branched-chain amino acid supplements are now being recommended to be taken before contact sports to reduce concussions.
Ezek Mathew, Nathan Jones, McKinley Dews, Dominique Neal, Anders Cohen   +4 more
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Neutrophils as a source of branched-chain, aromatic and positively charged free amino acids

Cell Adhesion & Migration, 2019
Neutrophils release branched-chain (valine, isoleucine, leucine), aromatic (tyrosine, phenylalanine) and positively charged free amino acids (arginine, ornithine, lysine, hydroxylysine, histidine) when adhere and spread onto fibronectin.
Svetlana I. Galkina, Natalia V. Fedorova, Alexander L. Ksenofontov, Vladimir I. Stadnichuk, Ludmila A. Baratova, Galina F. Sud’Ina   +5 more
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