Results 111 to 120 of about 2,480,811 (338)

Rate constants measured for hydrated electron reactions with peptides and proteins [PDF]

open access: yes, 1968
Effects of ionizing radiation on the amino acids of proteins and the reactivity of the protonated amino group depends upon the pK subscript a of the group.
Braams, R.
core   +1 more source

Supernovae, Neutrinos, and the Chirality of the Amino Acids

open access: yes, 2011
A mechanism for creating an enantioenrichment in the amino acids, the building blocks of the proteins, that involves global selection of one handedness by interactions between the amino acids and neutrinos from core-collapse supernovae is described.
Boyd, R. N., Kajino, T., Onaka, T.
core   +1 more source

Amino Acid Imbalance [PDF]

open access: yesProceedings of the Nutrition Society, 1965
A E, Harper, Q R, Rogers
openaire   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Investigating metabolic dysregulation in serum of triple transgenic Alzheimer’s disease male mice: implications for pathogenesis and potential biomarkers

open access: yesAmino Acids
Alzheimer’s disease (AD) is a multifactorial neurodegenerative disease that lacks convenient and accessible peripheral blood diagnostic markers and effective drugs.
Hongbin Zhuang   +9 more
doaj   +1 more source

Free amino acids of the blood and some organs in hypokinesia [PDF]

open access: yes
The metabolic fund of amino acids of the blood and tissues of rats under hypokinesia was investigated. The content of free amino acids was determined for the liver, kidney, brain, and the skeletal and cardiac muscles after established periods of ...
Kobylyanskiy, L. N.   +3 more
core   +1 more source

Factors affecting protein synthesis in vitro in rabbit reticulocytes [PDF]

open access: yes, 1957
Rabbit reticulocytes in vitro rapidly incorporate labeled amino acids into their proteins. The process is accelerated by the plasma of every mammal investigated and also by extracts of normal erythrocytes, rabbit reticulocytes, liver, spleen, and yeast ...
Borsook, Henry   +2 more
core  

Strength through diversity: how cancers thrive when clones cooperate

open access: yesMolecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken   +3 more
wiley   +1 more source

Intersubunit communication in glycogen phosphorylase influences substrate recognition at the catalytic sites

open access: yesAmino Acids
Glycogen phosphorylase (GP) is biologically active as a dimer of identical subunits, each activated by phosphorylation of the serine-14 residue. GP exists in three interconvertible forms, namely GPa (di-phosphorylated form), GPab (mono-phosphorylated ...
Nahori Kamada   +3 more
doaj   +1 more source

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