Results 121 to 130 of about 1,395,787 (296)

Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K

FEBS Open Bio, EarlyView.
We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley   +1 more source

Structure-activity relationship of amino acid analogs to probe the binding pocket of sodium-coupled neutral amino acid transporter SNAT2

Amino Acids
The sodium-coupled neutral amino acid transporter SNAT2 (SLC38A2) has been shown to have important physiological functions and is implicated in various diseases like cancer.
Sebastian Jakobsen, Maria Pedersen, Carsten Uhd Nielsen   +2 more
doaj   +1 more source

Amino acid requirements and amino acid supply in the sheep [PDF]

Proceedings of the Nutrition Society, 1973
D. G. Armstrong, E. F. Annison
openaire   +3 more sources

Cis‐unsaturated sphingolipids support growth of sphingoid base‐deficient yeast but impair plasma membrane integrity

FEBS Open Bio, EarlyView.
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi, Saki Sugihara, Yohei Ishibashi, Kono Yushi, Hazuki Yamauchi, Motohiro Tani   +5 more
wiley   +1 more source

Pharmacokinetics of L-theanine and the effect on amino acid composition in mice administered with L-theanine

Amino Acids
L-theanine, an amino acid component of the tea leaves of Camellia sinensis, is sold in Japan as a supplement for good sleep. Although several studies in humans and mice have reported the effects of L-theanine on brain function, only a few reports have ...
Shinnosuke Yamaura, Koki Sadamori, Reiko Konishi, Takashi Majima, Akira Mukai, Kyosuke Uno, Toshihiko Kinjo, Koji Komori, Nobuyuki Kuramoto, Kou Kawada   +9 more
doaj   +1 more source

ESTIMATION OF GROWTH REQUIREMENTS FOR AMINO ACIDS BY ASSAY OF THE CARCASS

, 1954
Harold H. Williams, L. V. Curtin, J. Abraham, J.K. Loosli, L. A. Maynard   +4 more
openalex   +1 more source

Phosphomimetic mutations near active sites of proteins in Thermus thermophilus suggest a widespread regulatory mechanism

FEBS Open Bio, EarlyView.
In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki, Hiroki Okanishi, Yoshikatsu Kanai, Ryoji Masui   +3 more
wiley   +1 more source

Identification and characterization of endogenous biomarkers for hepatic vectorial transport (OATP1B3-P-gp) function using metabolomics with serum pharmacology

Amino Acids
The organic anion-transporting polypeptide 1B3 and P-glycoprotein (P-gp) provide efficient directional transport (OATP1B3-P-gp) from the blood to the bile that serves as a key determinant of hepatic disposition of the drug.
Yong-wen Jin, Yan-rong Ma, Ming-kang Zhang, Wen-bin Xia, Pei Yuan, Bo-xia Li, Yu-hui Wei, Xin-an Wu   +7 more
doaj   +1 more source

Amino-acid requirements of amylase synthesis by pigeon-pancreas slices [PDF]

, 1951
L E Hokin
openalex   +1 more source

Microbial profile of the appendix niche in acute appendicitis: a novel sampling approach

FEBS Open Bio, EarlyView.
This study utilized a novel sampling method, ERAT (i.e. endoscopic retrograde appendicitis treatment)‐guided lumen aspiration, to obtain samples from the appendix, and shotgun metagenomic sequencing was performed for in situ characterization of the appendix microbiome in patients with acute appendicitis.
Huimin Ma, Mingfei Wang, Yanhu Feng, Wanqi Zhang, Wenbo Wang, Yanfeng Xie, Guixiang Kong, Jie Feng, Pengfei Wang, Qi Wang, Xiaojun Huang   +10 more
wiley   +1 more source