Results 151 to 160 of about 1,395,787 (296)

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Stable Nitrogen Isotope Analysis of Amino Acids by Orbitrap Mass Spectrometry: Application for Extraterrestrial Samples. [PDF]

Rapid Commun Mass Spectrom
McIntosh OM, Baczynski AA, Matney M, McLain HL, Farnsworth KK, Dworkin JP, Glavin DP, Elsila JE, Xie H, Freeman KH.   +9 more
europepmc   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

The Molecular Basis of Amino Acids Sensing. [PDF]

Adv Sci (Weinh)
Jiang C, Tan X, Jin J, Wang P.
europepmc   +1 more source

The Microbiological Determination of Amino Acids in “Shoyu”

, 1952
Toshinao TSUNODA, Z. ISHIZUKA, Sanzo Miyazawa, Gakuzo Tamura   +3 more
openalex   +2 more sources

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

N-Lactoyl Amino Acids: Emerging Biomarkers in Metabolism and Disease. [PDF]

Diabetes Metab Res Rev
Naja K, Hedaya L, Elashi AA, Rizzo M, Elrayess MA.   +4 more
europepmc   +1 more source

On Proteins and Amino Acids

, 1954
Hajime Masamune, Sen‐itiroh Hakomori, Osamu Masamune   +2 more
openalex   +2 more sources

Cloning, expression, purification, and structural modeling of the Chandipura virus matrix protein

FEBS Open Bio, EarlyView.
This research protocol offers a guide for the cloning, expression, and purification of the Chandipura virus matrix protein using E. coli. It also includes a step‐by‐step procedure for cloning, expressing, and conducting fluorescence imaging of GFP‐fused Chandipura virus matrix protein in mammalian cell lines.
Mariana Grieben
wiley   +1 more source

Development of the Direct Deuteration Method for Amino Acids and Characterization of Deuterated Tryptophan. [PDF]

Bioengineering (Basel)
Shibazaki C, Sugiyama H, Ueda M, Oku T, Adachi M, Fisher Z, Akutsu-Suyama K.   +6 more
europepmc   +1 more source