Results 181 to 190 of about 7,358,369 (397)

Structure determination needs to go viral

open access: yesAmino Acids
Viral diseases are expected to cause new epidemics in the future, therefore, it is essential to assess how viral diversity is represented in terms of deposited protein structures.
Matheus de Bastos Balbe e Gutierres   +3 more
doaj   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

open access: yesFEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal   +3 more
wiley   +1 more source

Altered amino acid levels in young hypopituitarism: impact of NAFLD and insulin resistance

open access: yesAmino Acids
Elevated concentrations of amino acids (AAs) are commonly observed in patients with nonalcoholic fatty liver disease (NAFLD). Individuals with hypopituitarism (HP) are at a heightened risk of developing NAFLD due to factors such as visceral obesity ...
Yuwen Zhang   +3 more
doaj   +1 more source

Alkane biosynthesis gene expression and its increased production in recombinant cyanobacteria

open access: yesFEBS Open Bio, EarlyView.
The transcription and mRNA structures of the alkane biosynthesis genes ado/aar were analysed in the representative cyanobacteria PCC 6803 and SK1‐2‐1, which produce C17H36 and C15H32, respectively. PCC 6803 transconjugants carrying these genes showed a 1.8‐ to 2.3‐fold increase in C17H36 production.
Misato Nagao   +4 more
wiley   +1 more source

Plasma d-asparagine and the d/l-serine ratio reflect chronic kidney diseases in children regardless of physique

open access: yesAmino Acids
Biomarkers that accurately reflect renal function are essential in management of chronic kidney diseases (CKD). However, in children, age/physique and medication often alter established renal biomarkers.
Toshimasa Morishita   +11 more
doaj   +1 more source

COMPARATIVE STUDIES OF THE METABOLISM OF THE AMINO ACIDS

open access: hybrid, 1931
Noel F. Shambaugh   +2 more
openalex   +1 more source

A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites

open access: yesNature, 2017
Dylan Dodd   +10 more
semanticscholar   +1 more source

Positive feedback loop between MAPK and aquaporin 7 regulates autophagy and apoptosis induced by palmitate in RIN‐m5f cells

open access: yesFEBS Open Bio, EarlyView.
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy