Results 131 to 140 of about 5,128,888 (403)

Effect of Constraint-Induced Movement Therapy on Motor Function of Rats with Cerebral Ischemia-Reperfusion Injury Based on Magnetic Resonance Spectroscopy Imaging

康复学报, 2023
ObjectiveAnimal magnetic resonance spectroscopy (MRS) imaging was used to detect the level of glutamate and γ-aminobutyric acid in motor cortex of rats, and to explore the regulatory effect of constraint-induced movement therapy (CIMT) on motor function ...
JIANG Pingli, CHEN Xiaocheng, XU Wenshan, DING Yanyi, LIU Weilin, TAO Jing   +5 more
doaj  

Trends in gabapentinoid prescribing: A nationwide Danish drug utilization study

British Journal of Clinical Pharmacology, EarlyView.
Aims Pregabalin and gabapentin are increasingly used for pain and other conditions. Concerns exist about overuse as well as potential misuse and abuse. To guide rational prescribing practices, we provide detailed nationwide data on the use of gabapentinoids in Denmark.
Anton Pottegård, Lotte Rasmussen, Morten Olesen, Anne Mette Skov Sørensen, Zandra Nymand Ennis, Joseph Kane, Sarah Baxter, Blánaid Hicks   +7 more
wiley   +1 more source

Linking chronic stress to insomnia symptoms in older adults: The role of stress co‐occurrence during the pandemic

Research in Nursing &Health, Volume 46, Issue 1, Page 68-79, February 2023., 2023
Abstract Studies examining the associations of chronic stressors with sleep health in older adults have shown conflicting results. While the COVID‐19 pandemic increased perceived stress at the population level, less is known about chronic stressors experienced by older adults in the context of the COVID‐19 pandemic and its impact on sleep health in an ...
Wan‐Chin Kuo, Anne L. Ersig, Fatih Kunkul, Roger L. Brown, Linda D. Oakley   +4 more
wiley   +1 more source

Are Strong Bronsted Acids Necessarily Strong Lewis Acids? [PDF]

arXiv, 2006
The Broensted and Lowry acid base theory is based on the capacity of proton donation or acceptance (in the presence or absence of a solvent) whereas the Lewis acid base theory is based on the propensity of electron pair acceptance or donation. We explore through DFT calculation the obvious question whether these two theories are in conformity with each
arxiv  

Tetramethylenedisulfotetramine alters Ca²⁺ dynamics in cultured hippocampal neurons: mitigation by NMDA receptor blockade and GABA(A) receptor-positive modulation. [PDF]

, 2012
Tetramethylenedisulfotetramine (TETS) is a potent convulsant that is considered a chemical threat agent. We characterized TETS as an activator of spontaneous Ca²⁺ oscillations and electrical burst discharges in mouse hippocampal neuronal cultures at 13 ...
Cao, Zhengyu, Hammock, Bruce D, Lein, Pamela J, McCoy, Mark, Pessah, Isaac N, Rogawski, Michael A   +5 more
core   +2 more sources

Submerged fermentation of Lactobacillus rhamnosus YS9 for γ-aminobutyric acid (GABA) production

Brazilian Journal of Microbiology, 2013
γ-Aminobutyric acid (GABA) is a major inhibitory neurotransmitter in central nervous system, and its application in drugs and functional foods has attracted great attention.
Q. Lin
semanticscholar   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

The Factors of the Classification of Protein Amino Acids [PDF]

This paper is published in GLASNIK of Montenegrin Academy of Science and arts, 2000, 13, pp. 173-194, 2006
In this work it is shown that three pairs of the factors appear to be the key, i.e. main factors of a natural classification of protein (canonical) amino acids within the amino acid (genetic) code. First pair: the factors of the habit of an amino acid molecule (size and polarity).
arxiv  

Prebiotic Organic Microstructures [PDF]

, 2011
Micro- and sub-micrometer spheres, tubules and fiber-filament soft structures have been synthesized in our experiments conducted with 3 MeV proton irradiations of a mixture of simple inorganic constituents, CO, N2 and H2O.
A Yoshihara, AM Hessler, CJ Hale, DI Foustoukos, F Klein, H Kurihara, J Takahashi, K Kobayashi, K Kobayashi, K Kobayashi, K Kobayashi, K Kvenvolden, Kensei Kobayashi, M Yoshizaki, Marie-Paule Bassez, MP Bassez, MP Bassez, O Botta, S Miyakawa, SL Seewald, T McCollom, T McCollom, Y Takano, Y Takano, Y Takano, Y Takano, Yoshinori Takano   +26 more
core   +2 more sources

Highly‐Selective Electrochemical Decarboxylative Late‐Stage Functionalization of Amino Acids

Chemistry – A European Journal, EarlyView.
Electrochemical decarboxylative late‐stage functionalization of the C‐ or N‐terminus of natural amino acids is presented. Metal and catalyst‐free protocol widely explored the synthesis of hindered ethers, amines, or di‐peptide. Abstract A unified electrochemical decarboxylative strategy for the site‐selective construction of carbon‐heteroatom bonds is ...
Adrija Ghosh, Vishal Kumar Parida, Tristan von Münchow, Lutz Ackermann, Debasis Banerjee   +4 more
wiley   +1 more source