Results 171 to 180 of about 5,172,296 (338)

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Effect of different conditions on the germination of coix seed and its characteristics analysis

Food Chemistry: X
Coix seed (CS) has high nutritional value, but the deep processing of CS is relatively limited. Sprouting can significantly improve nutritional value, laying the foundation for efficient consumption or further processing.
Lidan Dong, Yun Yang, Yongcai Zhao, Zhengyu Liu, Cuiqin Li, Laping He, Lihua Liu   +6 more
doaj  

Involvement of upregulation of miR-210 in a rat epilepsy model

Neuropsychiatric Disease and Treatment, 2016
Licheng Chen, Hao Zheng, Shimeng Zhang Neurological Department of Internal Medicine, Linyi People’s Hospital of Shandong Province, Linyi, People’s Republic of China Abstract: Epilepsy is a common type of neurological disorder with ...
Chen L, Zheng H, Zhang S
doaj  

Alterations and mechanistic insights of gut microbiota and its metabolites in type 2 diabetes mellitus and Alzheimer's disease

iMetaOmics, EarlyView.
This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu, Yu An, Yage Du, Zhaoming Cao, Jie Zheng, Jingya Wang, Tingyi Li, Xingen Lei, Yanhui Lu   +8 more
wiley   +1 more source

Synthesis of N-(N-Acetyl-L-aspartyl)-4-aminobutyric Acid (Ac-Asp-gammaAbu). [PDF]

, 1979
Thrina Loennechen, Erik A. Hagen, Arne Jørgen Aasen, Olof Wennerström, Curt R. Enzell, William W. Reid, Noboru Yanaihara, Chizuko Yanaihara   +7 more
openalex   +1 more source

Distinctive metabolic disturbances associated with redox homeostasis, nervous and hormonal functions during gut microbial enrichment upon polystyrene microplastic exposure

iMetaOmics, EarlyView.
Microplastic‐induced gut microbial enrichment was dominated by bacteria within Eubacteriales, correlated with the virome, and accompanied by colitis. The polyamine synthetic pathway was activated to maintain glutathionylspermidine homeostasis, concurrent with decreases in pathways involved in the production of energy and reactive oxygen species under ...
Guozhu Ye, Zeming Wu, Guoyou Chen, Xuyi Liu, Yifang Duan, Minghui Li, Qiansheng Huang   +6 more
wiley   +1 more source

Unveiling the potential biochemical effects of selected heterocyclic compounds as human Type-A γ-aminobutyric acid (GABA A) Modulator: An Insilico Approach

Biotechnology Reports
Background: Investigating the bioactivities of zuranolone derivatives as Type-A γ-aminobutyric acid inhibitors which will thereby down-regulate postpartum depression is considered a crucial study.
Abel Kolawole Oyebamiji, Sunday Adewale Akintelu, Oluwakemi Ebenezer, Faith Eniola Olujinmi, David O. Adekunle, Adesoji Alani Olanrewaju, Omowumi Temitayo Akinola, Samson Olusegun Afolabi, Ehimen Anastasia Erazua, Ayodeji Arnold Olaseinde   +9 more
doaj  

Cerebrospinal fluid gamma aminobutyric acid levels in migraine. [PDF]

, 1975
K.M.A. Welch, E Chabi, K Bartosh, V.S. Achar, Jerrold S. Meyer   +4 more
openalex   +1 more source

Soyasaponin and vertical microbial transmission: Maternal effect on the intestinal development and health of early chicks

iMeta, EarlyView.
This study investigates the vertical transmission of maternal microbiota in chickens and how it is modulated by maternal soyasaponin supplementation. Using a model spanning the reproductive tract, egg components, and developing chicks, we show that maternal gut and reproductive microbiota, including Bifidobacterium adolescentis (B.
Mingkun Gao, Shu Chen, Hao Fan, Peng Li, Aiqiao Liu, Dongli Li, Xiaomin Li, Yongfei Hu, Guofeng Han, Yuming Guo, Zengpeng Lv   +10 more
wiley   +1 more source

Effects of Lycopene and Sodium Valproate on Pentylenetetrazol-Induced Kindling in Mice

Iranian Journal of Medical Sciences, 2016
Sodium valproate and tomato extract have been studied in different experimental models of epilepsy individually. The aim of the present study was to evaluate the effect of lycopene on the antiepileptic effects of sodium valproate against ...
Vinay Kumar, Sandeep Kumar Sharma, K Nagarajan, Praveen Kumar Dixit   +3 more
doaj