Results 181 to 190 of about 5,282,507 (400)

Practical Applications of Secondary/Extractive Electrospray Ionization (SESI): A Versatile Tool for Real‐Time Chemical Analysis

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo   +5 more
wiley   +1 more source

Glutamate and Gamma-Aminobutyric Acid Systems in the Pathophysiology of Major Depression and Antidepressant Response to Ketamine

open access: yesBiological Psychiatry, 2017
M. Lener   +6 more
semanticscholar   +1 more source

Convergence Deficits in Myoclonus‐Dystonia Point to Cerebellar Impairment

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Myoclonus‐dystonia (M‐D) is a monogenic movement disorder, with proposed cerebellar dysfunction. Vergence eye movement deficits, characteristics of degenerative cerebellar disease, have not been studied in M‐D. Cerebellar transcranial alternating current stimulation (tACS) is considered a potential therapeutic approach.
Skadi Gerkensmeier   +13 more
wiley   +1 more source

Effects of Lycopene and Sodium Valproate on Pentylenetetrazol-Induced Kindling in Mice

open access: yesIranian Journal of Medical Sciences, 2016
Sodium valproate and tomato extract have been studied in different experimental models of epilepsy individually. The aim of the present study was to evaluate the effect of lycopene on the antiepileptic effects of sodium valproate against ...
Vinay Kumar   +3 more
doaj  

Cerebrospinal Fluid Proenkephalin Predicts Striatal Atrophy Decades before Clinical Motor Diagnosis in Huntington's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Huntington's disease (HD) is characterized by early, selective, progressive vulnerability of striatal medium spiny neurons (MSNs). Proenkephalin (PENK), a precursor of opioid peptides abundantly expressed in MSNs, is a promising biomarker of striatal integrity, but region‐specific associations and its potential for early‐stage ...
Mena Farag   +14 more
wiley   +1 more source

Involvement of upregulation of miR-210 in a rat epilepsy model

open access: yesNeuropsychiatric Disease and Treatment, 2016
Licheng Chen, Hao Zheng, Shimeng Zhang Neurological Department of Internal Medicine, Linyi People’s Hospital of Shandong Province, Linyi, People’s Republic of China Abstract: Epilepsy is a common type of neurological disorder with ...
Chen L, Zheng H, Zhang S
doaj  

Morphological Changes in Direct Pathway Striatal Neurons in a Rat Model of Tardive Dyskinesia

open access: yesMovement Disorders, EarlyView.
Abstract Background Tardive dyskinesia (TD) and drug‐induced parkinsonism (DIP) arise from prolonged dopamine antagonist use. Although D2 receptor hypersensitivity in the indirect pathway is a proposed mechanism, the role of the direct pathway remains unclear.
Hiroki Hikichi   +6 more
wiley   +1 more source

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