Results 191 to 200 of about 5,282,507 (400)

Multi‐Solvent Suppression Ultrafast 2D COSY for High‐Throughput Wine Screening

open access: yesMagnetic Resonance in Chemistry, EarlyView.
An interleaved ultrafast COSY with multi‐solvent suppression was developed for wine analysis to overcome limitations often associated with 1D 1H NMR (signal overlap) and conventional 2D NMR (long acquisition times) methods. Within an acquisition time of ~20 min, it revealed hidden metabolite peaks and cross peaks for improved annotation and ...
Pia S. Mayer   +5 more
wiley   +1 more source

Frontal Gamma-Aminobutyric Acid Concentrations Are Associated With Cognitive Performance in Older Adults.

open access: yesBiological Psychiatry: Cognitive Neuroscience and Neuroimaging, 2017
E. Porges   +10 more
semanticscholar   +1 more source

Simultaneous Detection of GABA and Glycine Using MEGA‐PRESS With TE Optimization at 3T

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To achieve the simultaneous acquisition of gamma‐aminobutyric acid (GABA) and glycine (Gly) using a MEGA‐PRESS sequence with an optimized TE at 3T. Methods MEGA‐PRESS simulations were performed at TEs 60‐88 ms to determine the optimal TE for Gly detection with minimal myo‐Inositol (mI) overlap and maximal GABA detection sensitivity ...
Justin R. Singer, Kimberly L. Chan
wiley   +1 more source

Abietic Acid Enhances the Sedative Activity of Diazepam: In vivo Approach along with Receptor Binding Affinity and Molecular Interaction with the GABAergic System

open access: yesChemistryOpen, EarlyView.
Abietic acid (AA) reveals potent sedative potential by expressing fast sleeping onset and increased sleeping duration compare to the control group in thiopental sodium induced sleeping mice. The compound also exhibited notable binding affinity (–7.9 kcal/mol) toward GABAA receptors.
Meher Afroz   +10 more
wiley   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

open access: yesPediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu   +4 more
wiley   +1 more source

Biochar and γ-Aminobutyric acid partnership improves rice productivity and mitigates Sb + Pb toxicity in co-contaminated soil. [PDF]

open access: yesBMC Plant Biol
Aamer M   +10 more
europepmc   +1 more source

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