Results 221 to 230 of about 5,128,888 (403)
European Journal of Neurology, Volume 30, Issue 2, Page 474-489, February 2023., 2023 Our retrospective study analyzed 40 patients with intensive care unit (ICU)‐dependent autoimmune encephalitis (AE) for clinical characteristics, diagnostics, prognostic factors, and clinical outcomes regarding standard treatment in responsive patients versus additional escalation therapies for treatment‐refractory cases.
Lisa Schwarz +4 more
wiley +1 more source
Stereoselective Syntheses of Optically Active Amino Acids from Methyl Esters of Alpha-keto Acids [PDF]
Stereoselective syntheses of optically active amino acids from methyl esters of alpha-keto ...
Harada, K., Matsumoto, K.
core +1 more source
CARDIOREGULATION IN LIMULUS. II. GAMMA AMINOBUTYRIC ACID, ANTAGONISTS AND INHIBITOR NERVES
, 1967 Ralph A. Pax, Richard C. Sanborn
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Medicinal Research Reviews, EarlyView.ABSTRACT Photoremovable protecting groups (PPGs) offer a straightforward solution for the temporary inactivation of biologically active substrates and their subsequent controlled release by light irradiation. Their relatively easy design and mode of application have made them useful tools for studying dynamic biological processes in vitro and in vivo ...
Bence Kontra +3 more
wiley +1 more source
Drug resistance in idiopathic generalized epilepsies: Evidence and concepts
Epilepsia, Volume 63, Issue 12, Page 3007-3019, December 2022., 2022 Abstract Although approximately 10%–15% of patients with idiopathic generalized epilepsy (IGE)/genetic generalized epilepsy remain drug‐resistant, there is no consensus or established concept regarding the underlying mechanisms and prevalence. This review summarizes the recent data and the current hypotheses on mechanisms that may contribute to drug ...
Joanna Gesche, Christoph P. Beier
wiley +1 more source
Modulation of γ-aminobutyric acid transport in nerve endings: Role of extracellular γ-aminobutyric acid and of cationic fluxes [PDF]
, 1978 Giulio Levi, Maurizio Raiteri
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High‐resolution, volumetric diffusion‐weighted MR spectroscopic imaging of the brain
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose To achieve high‐resolution, three‐dimensional (3D) quantitative diffusion‐weighted MR spectroscopic imaging (DW‐MRSI) for molecule‐specific microstructural imaging of the brain. Methods We introduced and integrated several innovative acquisition and processing strategies for DW‐MRSI: (a) a new double‐spin‐echo sequence combining ...
Zepeng Wang, Bradley P. Sutton, Fan Lam
wiley +1 more source
Lacosamide decreases neonatal seizures without increasing apoptosis
Epilepsia, Volume 63, Issue 12, Page 3051-3065, December 2022., 2022 Abstract Objective Many seizing neonates fail to respond to first‐line anticonvulsant medications. Phenobarbital, an allosteric modulator of γ‐aminobutyric acid type A (GABAA) receptors, has low efficacy in treating neonatal seizures and causes neuronal apoptosis. Nonetheless, it is one of the most used anticonvulsants in this age group.
Rachel L. Langton +4 more
wiley +1 more source
A New Synthesis and the Crystal Structure of (RS)-2-Hydroxy-4-aminobutyric Acid Hydrochloride Monohydrate, an Inhibitor of GABA Uptake. [PDF]
, 1979 Lotte Brehm +8 more
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