Results 281 to 290 of about 5,172,296 (338)

EEG signal dimension is an index of seizure propensity and antiseizure medication effects in a mouse model of acquired epilepsy

Epilepsia, EarlyView.
Abstract Objective Variability in the frequency, timing, and pattern of seizures may influence the assessment of the effect of antiseizure medications (ASMs) when measuring seizure frequency, especially in patients with infrequent seizures. A low seizure rate is an exclusion criterion for enrollment of patients with epilepsy in clinical trials and ...
Massimo Rizzi, Peter J. West, Annamaria Vezzani, Karen S. Wilcox, Alessandro Giuliani   +4 more
wiley   +1 more source

Effects of Pretreatment Methods on Gamma-Aminobutyric Acid Enrichment and Quality Improvement in Highland Barley Beverages. [PDF]

Foods
Yin X, Wang S, Wang Z, Wen H, Bai T, Zhang Y.   +5 more
europepmc   +1 more source

THE BIOSYNTHESIS AND CONTENT OF GAMMA-AMINOBUTYRIC ACID IN THE GOLDFISH RETINA

, 1972
Dominic Man-Kit Lam
openalex   +1 more source

Synaptic inhibitory dynamics drive benzodiazepine response in pediatric status epilepticus

Epilepsia, EarlyView.
Abstract Objective Pediatric status epilepticus (SE) is a medical emergency associated with significant morbidity. Benzodiazepines (BZPs) are the current first‐line treatment, but do not work in more than one third of children presenting with SE. Animal studies have shown that SE can cause changes in synaptic inhibition signaling that can ultimately ...
Tommaso Fedele, Richard J. Burman, Anne Steinberg, Giorgio Selmin, Georgia Ramantani, Richard E. Rosch   +5 more
wiley   +1 more source

A simple and effective method to enhance the level of gamma-aminobutyric acid in Chinese yam tubers while preserving its original appearance. [PDF]

Food Chem X
Wang Q, Chen Z, Gao X, Xu H, Cheng YY, Liu S, Wang W, Zhang Y, Meng D, Wang Y, Liao S, Xie C, Wang Y.   +12 more
europepmc   +1 more source

kcnb1 loss of function in zebrafish causes neurodevelopmental and epileptic disorders associated with γ‐aminobutyric acid dysregulation

Epilepsia, EarlyView.
Abstract Objective KCNB1 encodes an α‐subunit of the delayed‐rectifier voltage‐dependent potassium channel Kv2.1. De novo pathogenic variants of KCNB1 have been linked to developmental and epileptic encephalopathies (DEEs), diagnosed in early childhood and sharing limited treatment options.
Lauralee Robichon, Claire Bar, Anca Marian, Lisa Lehmann, Solène Renault, Edor Kabashi, Sorana Ciura, Rima Nabbout   +7 more
wiley   +1 more source

Prevalence, clinical characteristics, and risk factors for psychosis in people with epilepsy: A multicenter retrospective cohort study

Epilepsia, EarlyView.
Abstract Objective We aimed to assess the prevalence, clinical characteristics, and risk factors for psychosis in a cohort of people with epilepsy in West China. Methods We used retrospective information from databases of three tertiary epilepsy centers, which included follow‐up records from 2006 onward.
Sisi Shen, Hanlin Sun, Zaiquan Dong, Tong Yi, Josemir W. Sander, Dong Zhou, Jinmei Li   +6 more
wiley   +1 more source

β-aminobutyric acid does not induce defenses or increase Norway spruce resistance to the bluestain fungus Grosmannia penicillata. [PDF]

Physiol Plant
Huynh NB, Krokene P, Nybakken L, Čėsna V, Mageroy MH.   +4 more
europepmc   +1 more source

Sustained rescue of seizure control in patients with highly refractory chronic epilepsy using empiric immunotherapy

Epilepsia, EarlyView.
Abstract Objective Following emerging evidence of autoimmune‐associated seizures in medication‐refractory epilepsy, we began offering a trial of immunotherapy to selected patients. Here, we review this approach's treatment response, predictive clinical features, and utility.
Elisabeth Doran, Albert Kelly, Raluca Stanila, Laura Healy, Colin P. Doherty   +4 more
wiley   +1 more source