Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16285 Abstract Aim To conduct a postmarketing surveillance study of patients with Dravet syndrome in Japan to investigate the safety and effectiveness of long‐term, real‐world, clinical use of stiripentol (STP).
Yuki Kitamura+6 more
wiley +1 more source
Gamma-aminobutyric acid for delaying type 1 diabetes mellitus: an update. [PDF]
Sutedja JC, Liyis BG, Saraswati MR.
europepmc +1 more source
Why does infantile epileptic spasms syndrome (IESS) occur with a variety of underlying conditions and why does it respond to adrenocorticotrophin hormone (ACTH)/corticosteroids? Our scoping review summarizes five hypotheses from the literature: gene/epigenetic regulation, stress/HPA axis activation, neuroinflammation/immune function, altered neuronal ...
Emily A. Innes+6 more
wiley +1 more source
Dexmedetomidine Reduces Presynaptic γ-Aminobutyric Acid Release and Prolongs Postsynaptic Responses in Layer 5 Pyramidal Neurons in the Primary Somatosensory Cortex of <i>Mice</i>. [PDF]
Tang B, Tang J, Huang Y.
europepmc +1 more source
This consensus highlights critical research gaps in obesity epidemiology, phenotypic heterogeneity and clinical management, calling for advanced methodologies, collaborative strategies and innovative policies to mitigate the global obesity epidemic and its socio‐economic impacts.
Federico Carbone+28 more
wiley +1 more source
Design, Synthesis and Biological Activity Study of γ-Aminobutyric Acid (GABA) Derivatives Containing Bridged Bicyclic Skeletons as BCAT1 Inhibitors. [PDF]
Luo W+9 more
europepmc +1 more source
A Cofactor Regeneration System for 2-Aminobutyric Acid Production Based on Combined Cross-Linked Enzyme Aggregates: Utilizing His-Tagged Enzymes With Low-Concentration Calcium Ions as Precipitant. [PDF]
Liu J+8 more
europepmc +1 more source
Dietary γ-Aminobutyric Acid Promotes Growth and Immune System Performance and Improves Erythropoiesis and Angiogenesis in Gibel Carp (Carassius auratus gibelio). [PDF]
Bai X+5 more
europepmc +1 more source