Results 21 to 30 of about 7,678 (194)

Comprehensive Regulation of Liquid–Liquid Phase Separation of Polypeptides

Molecules, 2023
The elucidation of the molecular driving forces responsible for Liquid–liquid Phase Separation (LLPS) of proteins and nucleic acids within living cells is crucial for understanding its biological functions and its role in related diseases. In the present
Yanwei Wang, Dongxin Xiang, Siyuan Chen, Guangcan Yang   +3 more
doaj   +1 more source

Glanzmann's thrombasthenia during pregnancy complicated by large subchorionic hematoma managed with antifibrinolytics, human leukocyte antigen-matched platelet transfusion, and primary cesarean delivery: a case report

AJOG Global Reports, 2022
A 29-year-old primipara with Glanzmann's thrombasthenia presented for prenatal care at 8 weeks of gestation. Pregnancy remained uncomplicated until 22 weeks of gestation when a subchorionic hematoma, measuring 5.8 × 4.1 × 6.7 cm, was diagnosed and ...
Veronica Winget, MD, MS, Monique Schoenhage, MD, MBA, Teresa Orth, MD, PhD   +2 more
doaj   +1 more source

IN VITRO STUDY OF ANTI-INFLUENZA ACTIVITY OF PARA-AMINOBENZOIC ACID AND PROSPECTS OF NASAL DRUG DEVELOPMENT [PDF]

Annals of Mechnikov's Institute, 2017
is a vitamin-like substance, para-aminobenzoic acid (PABA). The aim of this work is to study antiviral activity of para-aminobenzoic acid, ε-aminocaproic acid, and their mixture against influenza virus, to evaluate their cytotoxic effect and to calculate
Nefedova L., Boyko N., , Starosila D., Rybalko S., Zhilyakova E., Novikov O., Zhukovina O., Sagaydak-Nikitjuk R., Iurchenko I.   +8 more
doaj   +1 more source

Salts of S-(+)-Ibuprofen Formed via Its Reaction with the Antifibrinolytic Agents Aminocaproic Acid and Tranexamic Acid: Synthesis and Characterization

Crystals, 2023
The paucity of multi-component compounds containing the non-steroidal anti-inflammatory drug (NSAID) S-(+)-ibuprofen (S-IBU) in combination with other drugs prompted the present study, which describes 1:1 salts of this active pharmaceutical ingredient ...
Hannah M. Frösler, Humbelani S. Ramulumo, Cesarina Edmonds-Smith, Mino R. Caira   +3 more
doaj   +1 more source

Plasmin inhibitors prevent leukocyte accumulation and remodeling events in the postischemic microvasculature. [PDF]

PLoS ONE, 2011
Clinical trials revealed beneficial effects of the broad-spectrum serine protease inhibitor aprotinin on the prevention of ischemia-reperfusion (I/R) injury. The underlying mechanisms remained largely unclear.
Christoph A Reichel, Max Lerchenberger, Bernd Uhl, Markus Rehberg, Nina Berberich, Stefan Zahler, Matthias P Wymann, Fritz Krombach   +7 more
doaj   +1 more source

NMR spectroscopy of Cu(II) complexes with acrylamide and sodium acrylate copolymer and ω-amino acids

Журнал Белорусского государственного университета: Химия, 2021
Macromolecular complexes of acrylamide and sodium acrylate copolymer with microelements, including Cu(II), may form at preparation of crop protection and stimulation compositions, where the copolymer serves as an adhesive, water-retaining and film ...
Dmitry L. Kudryavsky, Elena K. Fomina, Lyudmila Yu. Tychinskaya, Evgeny D. Skakovsky, Svetlana E. Bogushevich   +4 more
doaj   +1 more source

In vitro study of the spectrum antiviral activity of aliphatic acid toward the prototype coronavirus strain

Biomedical and Biotechnology Research Journal, 2023
Background: The aim of this study was to perform an in vitro evaluation of the antiviral activity of several well-known organic substances against infectious bronchitis virus (IBV), the prototype strain of the coronavirus family.
Iryna V Dziublyk, Serhii O Soloviov, Olena P Trokhimenko, Oleksandr Ya Dziublyk, Mykhailo P Smetiukh, Oleh K Yakovenko, Volodymyr Vasylenko, Marina Sidorenko, Saulius Mickevicius, Mykola I Gumeniuk   +9 more
doaj   +1 more source

Cytokine Adsorption onto the Modified Carbon Sorbent Surface in vitro in Peritonitis

Общая реаниматология, 2009
Objective: to evaluate the efficiency of cytokine sorption with carbon with a locally aminocaproic acid-modified surface from the plasma of patients with general purulent peritonitis. Materials and methods.
T. I. Dolgikh, L. G. Pyanova, O. N. Baklanova, V. T. Dolgikh, L. S. Luzyanova, S. I. Filippov, T. F. Sokolova, A. N. Salanov, A. V. Glushchenko, A. V. Yershov, B. A. Reis, V. A. Likholobov   +11 more
doaj   +1 more source

Acquired hemophilia as the cause of life-threatening hemorrhage in a 94-year-old man: a case report

Journal of Medical Case Reports, 2010
Introduction Acquired factor VIII deficiency is a rare entity that can lead to severe and life-threatening bleeding. We describe a case of severe bleeding from the tongue secondary to acquired hemophilia and discuss treatment options, including ...
Blanchard Elizabeth, Raphael Jonelle, Kelesidis Theodoros, Parameswaran Rekha   +3 more
doaj   +1 more source

Epsilon-aminocaproic acid for treatment of fibrinolysis during liver transplantation [PDF]

, 1987
In 97 adult patients receiving liver transplants, the coagulation system was monitored by thrombelastography and by coagulation profile including PT; a PTT; platelet count; level of factors I, II, V, VII, VIII, IX, X, XI, and XII; fibrin degradation ...
Kang, Y, Lewis, JH, Starzl, TE, Niren, LS, Bontempo, FA, Russell, MW, Navalgund, A   +6 more
core   +1 more source