Results 41 to 50 of about 7,678 (194)
Autofluorescent Activity of Thermosensitive, Hemostatic, and Wound Healing Biopolymer Hydrogels
GelsThermosensitive biopolymer gelatin–alginate hydrogels are promising for use as dressings for wound healing and drug delivery. This work presents fluorescence arising from the internal fluorophores of alginate and gelatin biopolymers in thermosensitive ...
Sergey I. Petrushenko +7 more
doaj +1 more source
Light‐Driven Quadrupedal Walking Biohybrid Robot With Antagonistic Muscle‐Rings and Inclined Joints
Advanced Robotics Research, EarlyView.This work presents a light‐driven quadrupedal walking biohybrid robot powered by antagonistic muscle‐rings that achieve alternating walking gait. Optical training improved reproducibility of cultured muscle tissues, while caffeine treatment enhanced contractile force.
Shotaro Saito +5 more
wiley +1 more source
Advanced Science, EarlyView.Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao +25 more
wiley +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu +5 more
wiley +1 more source
, 1996 Excessive postoperative bleeding after heart operations continues to be a source of morbidity. This prospective double-blind study evaluated epsilon-aminocaproic acid as an agent to reduce postoperative bleeding and investigated its mode of action.
Vander Salm, Thomas J. +9 more
core +1 more source
Targeting hexokinase 2 to induce breast cancer cell senescence
British Journal of Pharmacology, EarlyView.Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof +8 more
wiley +1 more source
, 2006 Diffuse alveolar hemorrhage (DAH) after allogeneic hematopoietic stem cell transplantation (HSCT) is often fatal. Standard therapy with high-dose corticosteroid is not always effective.
Folz, Rodney J. +3 more
core +1 more source
Blood-saving effect of aminocaproic acid in total knee joint replacement [PDF]
, 2017 КОЛЕННОГО СУСТАВА АРТРОПЛАСТИКА ЗАМЕСТИТЕЛЬНАЯОСТЕОАРТРИТ КОЛЕННОГО СУСТАВААМИНОКАПРОНОВЫЕ КИСЛОТЫ /ТЕР ПРИМКРОВОПОТЕРЯ ХИРУРГИЧЕСКАЯ /ПРОФГЕМОРРАГИИ ПОСЛЕОПЕРАЦИОННЫЕ /ПРОФФИБРИНОЛИЗПЕРЕЛИВАНИЕ КРОВИПОСЛЕОПЕРАЦИОННЫЕ ОСЛОЖНЕНИЯ /ПРОФПРОТЕЗА ...
Balaboshka, K. B., Khadzkou, Y. K.
core +1 more source
Cryo‐EM structures of multiple‐peptide resistance factor (MprF) from Pseudomonas aeruginosa
The FEBS Journal, EarlyView.Cryo‐EM analysis of MprF from Pseudomonas aeruginosa reveals a dimeric enzyme, distinct from Rhizobium homologues. The soluble GNAT domain contains a dynamic amphipathic helix (TTH) that adopts different positions in detergent micelle and nanodisc, relative to the membrane.
Shaileshanand Jha, Kutti R. Vinothkumar
wiley +1 more source
Разработка и регистрация лекарственных средств, 2019 Introduction. Influenza and acute respiratory viral infection (hereinafter – ARVI) are serious diseases that affect up to 500 million people worldwide every year. From 27.3 to 41.2 million people are registered annually in Russia.
A. S. Karpova +2 more
doaj +1 more source