Assessing the Impact of the 2021 VWD Guidelines on the Diagnosis/Management of Low VWF Patients
ABSTRACT Introduction The 2021 ASH/ISTH/NHF/WFH VWD diagnosis guidelines recommend Type 1 VWD diagnoses for patients with (a) VWF <0.30 IU/mL or (b) ‘Low VWF’ 0.30–0.50 IU/mL with the presence of abnormal bleeding. This recommendation recategorizes ‘Low VWF’ patients with abnormal bleeding into Type 1 VWD.
Michael Dong +4 more
wiley +1 more source
Preventing perioperative bleeding in patients with inherited bleeding disorders [PDF]
Data sources: Cochrane Cystic Fibrosis and Genetic Disorders Group's Coagulopathies Trials Register, a regularly updated database informed by trials identified within electronic databases including MEDLINE.
Beacher, Nicholas, Watterson, Colin
core +1 more source
Seventh Åland Island Meeting on von Willebrand Disease
ABSTRACT Introduction The seventh Åland Island Meeting on von Willebrand Disease (VWD) was held on the Åland archipelago in Finland, from 26 to 28 September 2024. Aim The meeting brought together experts in the field of VWD from around the world to share the latest advances and knowledge in VWD.
Riitta Lassila +17 more
wiley +1 more source
COMPARATIVE EVALUATION OF THE EFFICACY OF AMINOCAPROIC AND TRANEXAMIC ACIDS DURING HEART SURGERY
Objectives. To perform a comparative analysis of the efficacy of aminocaproic (EACA) and tranexamic acid (TX) for heart surgery with cardiopulmonary bypass (CPB). Material and methods.
Osipenko D. V. +4 more
doaj +1 more source
Cordyceps is a genus of ascomycete fungi and used widely in fungal drugs. However, in-depth studies of the metabolites of wild Cordyceps species and their substituents are lacking. In this study, a liquid chromatography-tandem mass spectrometry (LC-MS/MS)
Shan Guo +11 more
doaj +1 more source
Platelet Levels Associated With Bleeding Risk for Dental Interventions: A Systematic Review
ABSTRACT Objectives To evaluate evidence in relation to postoperative bleeding in humans aged ≥ 16 with preoperative platelet counts < 50,000/μL, compared to those above, undergoing dental interventions. Methods Quantitative synthesis without meta‐analysis was conducted through an electronic search conducted on Ovid MEDLINE and Embase from 1946 to ...
Guang Xu David Lim +3 more
wiley +1 more source
IN SILICO STUDY OF THE ANTICORONAVIRAL ACTIVITY OF ALIPHATIC AMINOCARBOXYLIC COMPOUNDS [PDF]
Aim. To evaluate the potential interactions of short-chain aliphatic aminocarboxylic compounds with key coronavirus proteases—the main protease (Mpro) and papain-like protease (PLpro) of SARS-CoV-2 and IBV—using molecular docking. Methods.
Smetiukh M.P., Soloviov S.O.
doaj +1 more source
Abdominal trauma in dogs 2. management [PDF]
Trauma represents a big challenge for emergency doctors both in human and veterinary medicine. There have been great advancements in trauma medicine in people and these often provide an inspiration for veterinary surgeons.
Cortellini, S, Humm, K R
core +2 more sources
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin +7 more
wiley +1 more source
Successful Treatment of Intracranial Hemorrhage with Recombinant Activated Factor VII in a Patient with Newly Diagnosed Acute Myeloid Leukemia: A Case Report and Review of the Literature [PDF]
Intracranial hemorrhage (ICH) is a common complication in acute myeloid leukemia (AML) patients with an incidence rate of 6.3% [1]. Bleeding disorders related to disseminated intravascular coagulation (DIC) are common complications in AML cases [2 ...
Daniel Johnson +10 more
core +3 more sources

