Results 61 to 70 of about 7,678 (194)

Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition

The Journal of Physiology, EarlyView.
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin, Andrea Carrer, Federica Boscolo Nata, Elena Frigo, Federico Fogolari, Giovanna Lippe, Michela Carraro, Paolo Bernardi   +7 more
wiley   +1 more source

Reversal of ε-Aminocaproic Acid-Induced Massive Thromboemboli Using Tissue Plasminogen Activator During Cardiac Surgery: A Case Report

, 2019
ε-Aminocaproic acid is routinely used in cardiac surgery to prevent excess bleeding. It is rarely associated with thrombotic events. This case report illustrates the formation of intracardiac thrombi leading to massive pulmonary embolism during a ...
Roy, Kevin M, Govind R. Rajan, Kevin M. Roy, Rajan, Govind R   +3 more
core   +1 more source

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK Pathways

Arthritis &Rheumatology, Volume 78, Issue 7, Page 1535-1553, July 2026.
Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla, Maria Fresnadillo, Irene Sanchez‐Platero, Macarena de la Riva‐Bueno, Fernando Huete‐Toral, Gonzalo Carracedo, Carmen Conde, Yolanda Benitez, Pablo Minguez, Sandra Carolina Cifuentes, Joaquin Rams, Gabriel Herrero‐Beaumont, Raquel Largo, Aránzazu Mediero   +13 more
wiley   +1 more source

Intraorgan use of Hemoblock for prevention and arrest of bleedings in endoscopic excision of gastric polyps

Неотложная медицинская помощь, 2019
INTRODUCTION Bleedings after endoscopic removal of gastric polyps continue to be a relevant issue. A technique has been developed for infltrating the base of polyps with a new hemostatic agent Hemoblock to prevent bleedings during polypectomy.
S. G. Tereshchenko, A. V. Plotkin, L. V. Mecheva   +2 more
doaj   +1 more source

Upregulated PKM2 Protects Dopaminergic Neurons From Oxidative Damage Through Nrf2 Transactivation in an MPTP‐Induced Mouse Model of Parkinson's Disease

CNS Neuroscience &Therapeutics, Volume 32, Issue 6, June 2026.
Oxidative stress induced by MPTP promotes hnRNP A1/A2–dependent alternative splicing toward PKM2 in dopaminergic neurons. Elevated PKM2 transactivates Nrf2, enhances antioxidant gene expression, and protects neurons from oxidative damage and degeneration.
Meng Mei, Qian‐qian Miao, Meng‐ke Li, Hao‐ran Wang, Jian‐hua Ding, Gang Hu, Yao Wei   +6 more
wiley   +1 more source

Hydrogel Adhesives for Gastrointestinal Perforation: Design Principles and Applications

Exploration, Volume 6, Issue 3, June 2026.
There are few reviews on hydrogel adhesives that comprehensively highlight the design principles, factors affecting adhesion, and applications for gastrointestinal (GI) perforation repair. This review outlines the mainstream design approaches of hydrogel adhesives via covalent and noncovalent molecular interactions, illustrating the underlying adhesive
Yudi Pang, Shuai Tian, Qinyu Han, Yulin Deng, Jiatao Zhang, Enqiang Linghu, Qianqian Chen, Zhimin Wang   +7 more
wiley   +1 more source

Novel interactions between the C5‐C5aR1 Axis and IF1: Implications for kidney mitochondrial physiology and ischemia–reperfusion injury

Physiological Reports, Volume 14, Issue 11, June 2026.
Abstract Ischemia‐reperfusion injury (IRI) is a prevalent condition that predominantly afflicts hospitalized patients, inducing acute kidney injury (AKI). In recent years, complement 5 (C5) and its anaphylatoxin receptor C5aR1 have been implicated in driving kidney IRI and loss of function.
Madison McGraw, Amod Sharma, Dinesh Bhattarai, Neriman Gokden, LeeAnn Macmillan‐Crow, Nirmala Parajuli   +5 more
wiley   +1 more source

Microwave Assisted Selective Hydrolysis of Polyamides from Multicomponent Carpet Waste

Global Challenges, 2021
Selective hydrolysis of polyamide‐6 (PA‐6) and polyamide‐66 (PA‐66) from commercial multicomponent PA‐6/PA‐66/polypropylene (PP) carpet is demonstrated by a microwave‐assisted acid catalyzed hydrothermal process, yielding monomeric products and solid ...
Eva Bäckström, Karin Odelius, Minna Hakkarainen   +2 more
doaj   +1 more source

3D skeletal muscle model recapitulating the myostatin knockout phenotypic and mitochondrial metabolic features

Physiological Reports, Volume 14, Issue 12, June 2026.
3D muscle culture reproduces the metabolic characteristics associated with the myostatin knockout phenotype. Abstract 3D cell culture, using a variety of bioengineering techniques, enables muscle cells to be cultured in more structural and functional biomimetic conditions than 2D cell culture.
Barbara Vernus, Elodie Jublanc, Béatrice Chabi, Laurence Pessemesse, Zacharie Cheng‐Boivin, Benoit J. Gentil, Anne Bonnieu, Christelle Koechlin‐Ramonatxo, Bénédicte Goustard   +8 more
wiley   +1 more source

Acquired factor VII deficiency causing severe bleeding disorder secondary to AL amyloidosis of the liver

Hematology Reports, 2018
A 52 year-old male presented with neck pain after undergoing thyroidectomy for a goiter three weeks prior which was complicated by a neck hematoma requiring evacuation.
Anthony L. Nguyen, Muhammad Kamal, Ravi Raghavan, Gayathri Nagaraj   +3 more
doaj   +1 more source