Results 61 to 70 of about 2,712,858 (190)

The Antiviral Activity Study of Complex Drug with Aminocapronic Acid for Prevention of Influenza and ARVI

open access: yesРазработка и регистрация лекарственных средств, 2019
Introduction. Influenza and acute respiratory viral infection (hereinafter – ARVI) are serious diseases that affect up to 500 million people worldwide every year. From 27.3 to 41.2 million people are registered annually in Russia.
A. S. Karpova   +2 more
doaj   +1 more source

Exploring a Ugi‐Mediated Polymerization‐Induced Self‐Assembly Approach to Peptoid Particles

open access: yesMacromolecular Rapid Communications, Volume 47, Issue 19, 6 October 2026.
Ugi‐mediated polymerization‐induced self‐assembly (U‐PISA) enables the one‐pot synthesis of PEG‐stabilized polypeptoid nanoparticles under mild aqueous conditions. By tuning PEG molar mass and feed composition, tunable spherical and worm‐like nano‐objects are obtained.
Thi Phuong Thu Nguyen   +8 more
wiley   +1 more source

IN SILICO STUDY OF THE ANTICORONAVIRAL ACTIVITY OF ALIPHATIC AMINOCARBOXYLIC COMPOUNDS [PDF]

open access: yesBiotechnologia Acta
Aim. To evaluate the potential interactions of short-chain aliphatic aminocarboxylic compounds with key coronavirus proteases—the main protease (Mpro) and papain-like protease (PLpro) of SARS-CoV-2 and IBV—using molecular docking. Methods.
Smetiukh M.P., Soloviov S.O.
doaj   +1 more source

The cold case of state transition 7 (stt7) mutants of Chlamydomonas reinhardtii, solved by whole‐genome sequencing

open access: yesNew Phytologist, Volume 252, Issue 1, Page 145-162, October 2026.
Long‐read whole‐genome sequencing revealed extensive chromosomal rearrangements and aneuploidy in a widely used Chlamydomonas reinhardtii stt7‐1 mutant. The STT7 gene (shown in red) was found to be split between two rearranged chromosomes, providing a molecular explanation for the long‐standing failure of this mutant in genetic crosses.
Sandrine Bujaldon   +3 more
wiley   +1 more source

Antifibrinolytic Activity During Administration of Epsilon-Aminocaproic Acid

open access: yes, 1971
Utilizing an in vitro method for activated and nonactivated whole blood clotlysis determinations, the antifibrinolytic effect of epsilon-aminocaproic acid therapy was evaluated. Initially, the induced antifibrinolytic activity diminished within two hours
DONALD W. NIBBELINK
core   +1 more source

Intraorgan use of Hemoblock for prevention and arrest of bleedings in endoscopic excision of gastric polyps

open access: yesНеотложная медицинская помощь, 2019
INTRODUCTION Bleedings after endoscopic removal of gastric polyps continue to be a relevant issue. A technique has been developed for infltrating the base of polyps with a new hemostatic agent Hemoblock to prevent bleedings during polypectomy.
S. G. Tereshchenko   +2 more
doaj   +1 more source

Persistent Gingival Bleeding After Scaling: A Diagnostic Clue to von Willebrand Disease

open access: yesClinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Von Willebrand disease (VWD) is not a rare inherited bleeding disorder. However, it is frequently underdiagnosed because early mucocutaneous bleeding manifestations are often attributed to local factors such as inflammation or anatomical abnormalities, leading to delayed recognition of the underlying systemic disease. A 31‐year‐old Han Chinese
Huihui Zhang   +3 more
wiley   +1 more source

Cryo‐EM structures of multiple‐peptide resistance factor (MprF) from Pseudomonas aeruginosa

open access: yesThe FEBS Journal, Volume 293, Issue 17, Page 5318-5339, September 2026.
Multiple peptide resistance factor (MprF) is a bacterial enzyme that carries out the aminoacylation of lipid head groups. CryoEM analysis of MprF from Pseudomonas aeruginosa reveals a dimeric enzyme, distinct from its homologues in Rhizobium. The soluble GNAT domain contains a dynamic amphipathic helix (TTH) that adopts different positions in detergent
Shaileshanand Jha, Kutti R. Vinothkumar
wiley   +1 more source

Use of Topical Tranexamic Acid or Aminocaproic Acid to Prevent Bleeding After Major Surgical Procedures

open access: yes, 2012
OBJECTIVE: To evaluate the literature describing topical use of tranexamic acid or aminocaproic acid for prevention of postoperative bleeding after major surgical procedures.
Maria G Tanzi, Heather J Ipema
core   +1 more source

Evaluation of Antifibrinolytic Use in Anterior Cruciate Ligament Arthroscopic Reconstruction. A Prospective Clinical Trial

open access: yesOrthopaedic Journal of Sports Medicine
Objective: To evaluate the effectiveness of two antifibrinolytic drugs (tranexamic acid and epsilon-aminocaproic acid) in reducing postoperative hemarthrosis after anterior cruciate ligament reconstruction.
M.S. Navarro   +5 more
doaj   +1 more source

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