Results 111 to 120 of about 93,718 (253)

A comprehensive review of cluster methods for drug–drug interaction network

Quantitative Biology, Volume 14, Issue 1, March 2026.
Abstract The detection of drug–drug interaction (DDI) is crucial to the rational use of drug combinations. Experimentally, DDI detection is time‐consuming and laborious. Currently, researchers have developed a variety of computational methods to predict DDI.
Shuyuan Cao, Guixia Liu, Xiangrun Zhou, Ji Lv   +3 more
wiley   +1 more source

Antibiotics for the Treatment of Patients with Metallo-β-Lactamase (MBL)-Producing Gram-Negative Bacterial Infections

Antibiotics
Infections caused by MBL-producing Gram-negative bacterial pathogens have disseminated worldwide and are associated with considerable morbidity and mortality.
Matthew E. Falagas, Dimitrios S. Kontogiannis, Dimitrios Ragias, Stylianos A. Kakoullis   +3 more
doaj   +1 more source

Phenotypic and Genotypic Characterization of Antimicrobial Resistance in Thermophilic Campylobacter Species Isolated From Faecal Samples of Chicken and Turkey

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
High rates of multidrug resistance (MDR) and resistance genes against critical antibiotics, particularly quinolones and macrolides, were detected in poultry isolates. This finding poses a significant human health risk via the food chain and underscores the urgency of enhanced biosecurity measures.
Muazzez Yeşilyurt, Özgül Gülaydın, Aliye Gülmez Sağlam   +2 more
wiley   +1 more source

Molecular Screening and Antibiogram Profile of Multidrug‐Resistant Enteropathogenic Escherichia coli Isolated From Retail Chicken Meat

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
Multidrug‐resistant enteropathogenic Escherichia coli (MDR‐EPEC) were investigated in retail chicken meat from Bangladesh. Molecular confirmation, antibiogram profiling, and resistance gene detection revealed universal multidrug resistance with high MAR indices, indicating intense antimicrobial pressure and highlighting significant food safety and ...
Sakibul Haque Zilon, Hemayet Hossain, Md. Shahidur Rahman Chowdhury, Sojib Ahmed, Asikur Rahman, Sumaya Shargin Khan, Margia Akter, Bashudeb Paul, Mohammad Ali Zinnah, Monira Noor, Md. Mahfujur Rahman, Md. Masudur Rahman   +11 more
wiley   +1 more source

Antibiotic Resistance and Pathogenicity of Vibrio Species in Aquaculture: Implications for Fish Health and Food Safety in LMICs

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
Pathogenic Vibrio species isolated from aquaculture environments in low‐ and middle‐income countries exhibit elevated antimicrobial resistance and multiple virulence traits. These findings highlight significant risks to fish health and food safety, underscoring the need for strengthened antimicrobial stewardship, robust biosecurity measures and ...
Asiphe Hobe, Luyanda Msolo, Kingsley Ehi Ebomah, Ishmael Festus Jaja, James Wabwire Oguttu, Anthony Ifeanyi Okoh   +5 more
wiley   +1 more source

Comprehensive review of chemical strategies for the preparation of new aminoglycosides and their biological activities.

Chemical Society Reviews, 2018
Nishad Thamban Chandrika, S. Garneau‐Tsodikova   +1 more
semanticscholar   +1 more source

Isolation, Antibiogram and Factors Associated With Staphylococcus aureus From Fish at the Landing Site and Selected Restaurants in Central Gondar, Ethiopia: One Health Approach

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
This study identified Staphylococcus aureus in 26% of fish, hand and knife samples from Gondar, Ethiopia, with high multidrug resistance. Findings highlight unsafe handling practices and recommend improved hygiene, regular monitoring and targeted antibiotic use to reduce contamination risks and protect public health through a One Health approach ...
Misganaw Tezera Ayele, Asnakew Mulaw Berihun, Ambaye Kenubih Worku, Mengesha Ayehu Getnet   +3 more
wiley   +1 more source

Cryo‐EM structures of a MexB–MexY chimeric efflux pump reveal that large open clefts are intrinsic to the MexY porter domain

Acta Crystallographica Section F, Volume 82, Issue 3, Page 83-93, March 2026.
In this study, cryo‐EM structures of the chimeric RND transporter MexBYB, composed of MexB and MexY, are presented, revealing distinct symmetric‐like and asymmetric conformations under apo and drug‐supplemented conditions. These structures show that the unusually large open clefts observed in MexBYB, similar to those in MexY, represent a unique ...
Jiye Wang, Kenta Tsutsumi, Mika Hirose, Ryosuke Nakashima, Takayuki Kato, Kunihiko Nishino, Atsushi Nakagawa, Eiki Yamashita   +7 more
wiley   +1 more source

Intrapartum Antibiotic Prophylaxis and Child Health Outcomes: A Systematic Review and Meta‐Analysis of Observational Studies

BJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 4, Page 556-567, March 2026.
ABSTRACT Background With increasing use of intrapartum antibiotic prophylaxis (IAP) for the prevention of early‐onset Group B streptococcus (GBS) infections, there is concern about its long‐term consequences on child health. Objectives To synthesise the evidence of IAP exposure on autoimmune‐related diseases, obesity in childhood and microbial ...
Maedeh Moradi, Jessica A Grieger, Xiao Tong Teong, Leonie K Heilbronn   +3 more
wiley   +1 more source

Severe Hearing Loss in the World's First Successfully Captive‐Born Yangtze Finless Porpoise: Impact of High Underwater Sound Exposure and Congenital Hearing Disorders

Integrative Zoology, Volume 21, Issue 2, Page 331-342, March 2026.
The audiogram of the world's first successfully captive‐born Yangtze finless porpoise was on average 40 dB higher than conspecifics. Congenital hearing disorders and noise exposure may be the primary cause of porpoise's hearing loss. ABSTRACT Aquariums globally have seen significant growth in recent decades.
Zhitao Wang, Tomonari Akamatsu, Kexiong Wang, Ding Wang   +3 more
wiley   +1 more source