Results 101 to 110 of about 71,389 (251)
Nephrotoxic effects of aminoglycosides on the developing kidney
, 2013 Aminoglycosides are the most commonly used antibiotics in infants hospitalized in neonatal intensive care units. Despite their outstanding efficacy profile, aminoglycosides remain relatively toxic with a narrow therapeutic index and a potential to cause ...
Samira Samiee-Zafarghandy +1 more
core +1 more source
Anaesthetic management of a horse with acute kidney injury
Equine Veterinary Education, EarlyView.Summary Anaesthetic management of animals with acute kidney injuries (AKI) is complex and poses considerable risk. There are no publications describing management of anaesthetised horses with AKI. Perioperative and anaesthetic care of a Thoroughbred filly presented with traumatic injuries and subsequent AKI is described.
C. T. Quinn, K. J. Hughes, A. N. Walton
wiley +1 more source
Equine Veterinary Education, EarlyView.Summary Erysipelothrix rhusiopathiae was the causative agent of vegetative endocarditis and vertebral osteomyelitis in a 24‐year‐old Irish draught gelding that presented with prolonged history of intermittent pyrexia and tachycardia. Clinical investigations revealed persistently reduced neck mobility, tachydysrhythmia and episodic pyrexia up to 41°C ...
E. Kolovou +11 more
wiley +1 more source
Apicectomy and retrograde endodontic treatment for an unerupted mandibular cheek tooth
Equine Veterinary Education, EarlyView.Summary Apicectomy combined with retrograde endodontic therapy is well documented in human and small animal dentistry, but its application in horses remains limited. This report describes the technique in a 2‐year‐old Warmblood mare with an unerupted, infected mandibular cheek tooth (307) that could not be accessed orally. Clinical examination revealed
Patricia Trummer‐Schug +3 more
wiley +1 more source
Transgenic selection and underlying mechanisms in apicomplexan parasites
The FEBS Journal, EarlyView.Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju +2 more
wiley +1 more source
Role of aminoglycosides in the treatment of bacterial endocarditis
Aminoglycosides are often used in combination with glycopeptides and beta-lactams for the treatment of bacterial endocarditis caused by alpha-haemolytic streptococci, staphylococci and enterococci. Recommendations on dosing and duration of aminoglycoside
Graham JC, Gould FK
core +4 more sources
Inhibition of RNase P cleavage by aminoglycosides
, 1999 A number of aminoglycosides have been reported to interact and interfere with the function of various RNA molecules. Among these are 16S rRNA, the group I intron, and the hammerhead ribozymes.
Mikkelsen, Nils E, +3 more
core
The FEBS Journal, EarlyView.Human AIMP2 mutations lead to severe neurodevelopmental defects and brain atrophy. Using patient‐derived fibroblasts from two individuals, we show decreased AIMP2 protein levels and overall protein synthesis. In a zebrafish loss‐of‐function model, the lack of AIMP2 leads to an increase in cell death and results in smaller brains.
Patrick Mullen +10 more
wiley +1 more source
Susceptibility of 64 Corynebacterium striatum strains to six aminoglycosides.
, 2016 Susceptibility of 64 Corynebacterium striatum strains to six aminoglycosides.
Marta Fernández-Martínez (3391568) +4 more
core +1 more source
Hypophosphataemia in adults: approach to diagnosis and management
Internal Medicine Journal, EarlyView.Abstract Hypophosphataemia is a common electrolyte disorder which can have clinically significant consequences for bone, muscle, neurological and haematological function. Its causes range from transient transcellular shifts in hospitalised patients to chronic renal phosphate‐wasting disorders mediated by fibroblast growth factor 23 (FGF23).
Kajanan Parameshwaran +2 more
wiley +1 more source