Results 111 to 120 of about 71,389 (251)

Extracellular DNA Shields against Aminoglycosides in Pseudomonas aeruginosa Biofilms

, 2013
Within recent years, it has been established that extracellular DNA is a key constituent of the matrix of microbial biofilms. In addition, it has recently been demonstrated that DNA binds positively charged antimicrobials such as aminoglycosides and ...
Høiby, Niels, Nielsen, Thomas Eiland, Nielsen, Thomas, Nilsson, Martin, Jensen, Peter Østrup, Chiang, Wen-Chi, Givskov, Michael, Tolker-Nielsen, Tim   +7 more
core   +1 more source

Temporal distribution of acute kidney injury–related hospitalizations after initiation of sodium–glucose cotransporter 2 inhibitors: A nationwide claims database analysis in older adults with an independent complementary single‐center eGFR analysis

Journal of Diabetes Investigation, EarlyView.
Among 190 older adults who experienced AKI‐related hospitalization after SGLT2 inhibitor initiation, 31.1% were hospitalized within 30 days. In an independent single‐center cohort, sustained early eGFR decline was associated with older age and use of one or two triple‐whammy‐related drug classes.
Kazuya Hiura, Ayana Tatsuno, Yamato Noto, Ryosuke Wakamatsu, Masayuki Sakunami, Ryu Kobayashi, Miki Yamashita   +6 more
wiley   +1 more source

Experimental and Clinical Approaches to Preventing Aminoglycoside-Induced Ototoxicity: A Scoping Review

Antioxidants
(1) Aminoglycosides remain indispensable in modern medicine but share a serious dose-limiting adverse effect: irreversible cochleovestibular ototoxicity. (2) This scoping review systematically maps experimental and clinical strategies aimed at preventing
Marek Zadrożniak, Maciej Biskupski, Marcin Szymański, Jarogniew J. Łuszczki   +3 more
doaj   +1 more source

Phenotypic Florfenicol Resistance in floR‐Harbouring Flavobacterium psychrophilum Isolates (CC‐ST90): A Case Study From Danish Freshwater Rainbow Trout Aquaculture

Journal of Fish Diseases, EarlyView.
ABSTRACT Monitoring antimicrobial resistance (AMR) in fish pathogens is essential for supporting sustainable aquaculture. In this study, susceptibility testing and genome sequencing were used to characterize the AMR profile of seven Flavobacterium psychrophilum originating from Danish rainbow trout farms (2019–2022).
Valentina L. Donati, Lone Madsen
wiley   +1 more source

Postantibiotic effect of aminoglycosides on gram-negative bacteria evaluated by a new method

, 1988
The in-vitro postantibiotic effect (PAE) of amikacin, gentamicin, netilmicin and tobramycin was investigated by a bioluminescent assay of bacterial ATP.
Isaksson, Barbro,, Nilsson, Lennart,, Maller, Rolf,, Sörén, Lars,   +3 more
core   +1 more source

Isolation and Identification of Erysipelothrix sp. in Hybrid Grouper (Epinephelus fuscoguttatus × E. lanceolatus) in Taiwan

Journal of Fish Diseases, EarlyView.
ABSTRACT In February 2025, a mortality event of unknown aetiology occurred at a hybrid grouper (Epinephelus fuscoguttatus × Epinephelus lanceolatus) aquaculture farm in southern Taiwan, with sporadic daily deaths persisting for a month. Four moribund groupers were collected over three sampling intervals for diagnostic investigation.
Shang‐Ting Wu, Yu‐Siang Lin, Chia‐Yu Hsieh   +2 more
wiley   +1 more source

Fluorinated aminoglycosides

ARKIVOC, 2019
Oscar M. Saavedra, Miguel A. Vilchis-Reyes   +1 more
doaj   +1 more source

Potentiation of Aminoglycoside Activity by A Pseudomonas aeruginosa Derived Enzyme Inhibitor against Multidrug-resistant Gram-positive Pathogens

Journal of Pure and Applied Microbiology
Multidrug-resistant (MDR) bacteria have posed a major clinical challenge, as many currently available antibiotics have lost their effectiveness. The development of new or improved antimicrobial formulations are required to address this problem. Collected
Mohammed S. Alosaimi
doaj   +1 more source

Pattern-based sensing of aminoglycosides with fluorescent amphiphiles [PDF]

A mixture of two amphiphiles with fluorescent head groups can be used as a sensing ensemble for the pattern-based analysis of aminoglycoside antibiotics. In buffered aqueous solution, the amphiphiles form a dynamic mixture of micellar aggregates.
Scopelliti, Rosario, Koestereli, Ziya, Severin, Kay   +2 more
core   +1 more source

Clinical Prediction Models for Acute Kidney Injury in Neonatology—A Systematic Review and Modelling Analysis

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aims Acute kidney injury (AKI) affects up to one‐third of neonates admitted to neonatal intensive care units (NICUs). NICUs are highly data‐rich environments, offering opportunities to develop clinical prediction rules (CPRs) that use clinical and demographic data to estimate AKI risk.
Dermot Wildes, Lisa Corley, Deirdre O'Sullivan, David T. Selewski, Caoimhe Costigan, Atif Awan, Catherine Quinlan, Michael A. Boyle   +7 more
wiley   +1 more source