Results 121 to 130 of about 71,389 (251)

Aminoglycosides and kidney function [PDF]

Journal of Medical Biochemistry, 2007
The aminoglycosides are bactericide antibiotics with predominant effecting on the Gramm-negative bacterias, then staphylococci and mycobacteria with a small therapeutic range and with expressive ototoxic, nephrotoxic and with rare neurotoxic side effects.
Stanić Momčilo, Mitić Radoslav, Jakovljević Milan   +2 more
doaj  

A Population Pharmacokinetic Model of Gentamicin in Hospitalized Neonatal Foals

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Information on safe and effective gentamicin dosing in foals is limited. This study aimed to provide guidance regarding optimal dosing regimens by means of a population pharmacokinetic (popPK) model. Gentamicin plasma concentration of 290 samples from 72 hospitalized foals (≤ 14 days old), treated with intravenous (IV) gentamicin, was measured
Astrid J. van den Brom‐Spierenburg, Esther A. Winter, Mathijs J. P. Theelen, Ingeborg M. van Geijlswijk, Cornélie M. Westermann, Marianne M. Sloet van Oldruitenborgh‐Oosterbaan, Tim Florschütz, Johannes C. Vendrig, Esther W. Siegers, Kim de Graaf, Marc Cherlet, Mathias Devreese, Ronette Gehring   +12 more
wiley   +1 more source

Genetic susceptibility to aminoglycoside cochleotoxicity in South African multidrug-resistant and rifampicin-resistant tuberculosis patients

South African Journal of Communication Disorders
Background: South Africa has a high burden of multidrug-resistant tuberculosis (MDR-TB) and rifampicin-resistant tuberculosis (RR-TB). At the time of this study, kanamycin formed part of the South African MDR/RR-TB treatment regimen.
Nazanin Ghafari, Lebogang Ramma, Richard Court, Noluthando Manyisa, Helen McIlleron, Lucretia Petersen   +5 more
doaj   +1 more source

Type IV‐Dominated Plasmid‐Encoded CRISPR‐Cas Systems Are Enriched in Multireplicon and Multi‐Stressor Resistance Plasmids Across the Global Plasmidome

Molecular Microbiology, EarlyView.
Screening 72,555 plasmid sequences reveals that intact CRISPR‐Cas systems are rare (1.03%) but strongly enriched in multireplicon and multi‐stressor resistance plasmids, with Type IV‐A as the dominant subtype. These findings implicate plasmid‐encoded CRISPR‐Cas as non‐randomly retained elements of structurally complex and high‐risk backbones.
Hannay Crystynah Almeida de Souza, Anamaria Mota Pereira dos Santos, Arlen Carvalho de Oliveira Almeida, Carlos Adam Conte Junior, Pedro Panzenhagen   +4 more
wiley   +1 more source

Application of guidelines for aminoglycosides use in French hospitals in 2013–2014

, 2017
on behalf of the Société de Pathologie Infectieuse de Langue Française (SPILF), the Observatoire National de l’Epidémiologie de la Résistance Bactérienne aux Antibiotiques (ONERBA) and the Surveillance de la Prescription des Antibiotiques (SPA ...
robert, jerome, Bru, J-P, Rabaud, C, Gauzit, R., Alfandari, S., Péan, Y., Bedos, J.P.   +6 more
core   +1 more source

Urban ants as potential mechanical vectors of pathogenic and antibiotic‐resistant bacteria in a Brazilian hospital

Medical and Veterinary Entomology, EarlyView.
Nine ant taxa were identified in a Brazilian hospital, with Tapinoma melanocephalum and Dorymyrmex brunneus being the most abundant. Eighty‐five percent of collected ants yielded detectable bacterial growth, including clinically relevant genera such as Acinetobacter, Pseudomonas, Escherichia coli and Pluralibacter.
Luana Biggi Souza, Anny Karoliny de Lima Dionisio, Mayara Acioli Cedrim, Luiz Carlos Silva Dias Neto, Ellymaira Freitas Pontes, Yáskara Veruska Ribeiro Barros, Renato Júnior Cavalcante da Silva, Ênio Jose Bassi, Jacques Hubert Charles Delabie, Ana Lucia Biggi Souza, Leticia Anderson   +10 more
wiley   +1 more source

Resistance patterns of Gram-negative bacteria to different aminoglycosides (Disk Diffusion method).

, 2013
Resistance patterns of Gram-negative bacteria to different aminoglycosides (Disk Diffusion method).
Heba A. Mohamed (355901), Gamal F. Gad (355900), Hossam M. Ashour (300566)   +2 more
core   +1 more source

Integrated Metabolomics and Selection Signal Analysis Provide Insights Into the Selection for Flavonol Biosynthesis Associated With Lettuce Quality Improvement

Plant Biotechnology Journal, EarlyView.
ABSTRACT Lettuce is a critical leafy vegetable consumed worldwide and is a substantial dietary source of health‐promoting compounds. Exploring changes in metabolism during lettuce domestication under artificial selection conditions is important to facilitate further breeding and cultivation for quality improvement.
Xiao Yang, Shiwei Wei, Ge Jin, Li Zhang, Ran Du, Yajun Wang, Chengcheng Shen, Tao Huang, Guotao Huo, Jie Peng, Bo Song, Fangyuan Zhang, Victor Hugo Escalona Contreras, Lijun Luo, Yuejian Li, Francisco A. Tomas‐Barberan, Bin Liu, Qichang Yang   +17 more
wiley   +1 more source

Mitochondrial mutation m.1555A>G and aminoglycoside-induced hearing loss in neonates: an integrative review

Frontiers in Pediatrics
ObjectiveTo evaluate the evidence related to the association between aminoglycoside-induced hearing loss and the mitochondrial mutation m.1555A>G, and to examine the potential clinical utility of pharmacogenetic prescription of aminoglycosides in ...
P. E. Edison, M. J. Sankar, Michael Hall
doaj   +1 more source

Effect of combinations of aminoglycosides on antibacterial activity by Checkerboard titration.

, 2013
Effect of combinations of aminoglycosides on antibacterial activity by Checkerboard titration.
Heba A. Mohamed (355901), Gamal F. Gad (355900), Hossam M. Ashour (300566)   +2 more
core   +1 more source