Results 121 to 130 of about 93,718 (253)

Biofilm Associated Persistence and Drug Tolerance in Mycobacteria Within Host Microenvironments

APMIS, Volume 134, Issue 3, March 2026.
ABSTRACT Biofilms formed by mycobacteria, particularly Mycobacterium tuberculosis (Mtb), represent a major challenge in tuberculosis (TB) treatment due to their highly organized structure and their capacity to induce phenotypic drug tolerance. These three‐dimensional bacterial aggregates are embedded in a self‐produced extracellular matrix that ...
Lourdes Serrano Garcia, Cesar Augusto Roque‐Borda, Fernando Rogério Pavan, Marlus Chorilli   +3 more
wiley   +1 more source

The Clinical Impact of Antibiotic Allergy Labels on One‐Year Outcomes of Solid Organ Transplant Recipients

Clinical Transplantation, Volume 40, Issue 3, March 2026.
ABSTRACT Antibiotic allergy labels (AALs) are common and often incorrect. They have many potential impacts, including the use of broader‐spectrum antibiotics and suboptimal treatment of infections. The impact of inaccurate allergy labels on post‐transplant outcomes in the solid organ transplant population is not well described.
Sashi Niranjan Nair, Paul Bigliardi, Lauren Fontana   +2 more
wiley   +1 more source

Diagnostic imaging and management of penetrating wounds of the foot

Equine Veterinary Education, Volume 38, Issue 3, Page 119-122, March 2026.
Summary Penetrating foot injuries in horses pose significant diagnostic and therapeutic challenges, particularly when deeper synovial structures are involved. A systematic approach to diagnostic imaging and early and aggressive management is essential to achieve a good outcome.
A. Scharf, J. Peroni
wiley   +1 more source

Distal urethral obstruction in an eight‐week‐old colt with struvite urolithiasis

Equine Veterinary Education, Volume 38, Issue 3, Page e130-e136, March 2026.
Summary An 8‐week‐old Thoroughbred colt presented with acute colic signs. Physical examination and transcutaneous ultrasound of the abdomen and penis revealed a urinary tract obstruction in the distal urethra due to urolithiasis. A distal urethrotomy over the site of obstruction was performed to remove the urolith and relieve the obstruction.
M. T. Connaughton, A. Wilson, C. M. Baldwin   +2 more
wiley   +1 more source

Equine botulism

Equine Veterinary Journal, Volume 58, Issue 2, Page 333-347, March 2026.
Abstract Botulism is a severe and often fatal disease in equine patients worldwide. Clostridium botulinum is a ubiquitous soil organism which produces a potent neurotoxin resulting in neuromuscular blockade and flaccid paralysis in affected animals. Definitive diagnosis is often impractical or impossible, leading to diagnosis and treatment based on ...
Kali Slavik, Robert Whitlock, Amy Johnson   +2 more
wiley   +1 more source

A systematic literature review and (network) meta-analysis of the effectiveness of ceftolozane/tazobactam versus aminoglycosides/polymyxins and ceftazidime/avibactam for treating adult patients with multidrug-resistant <i>Pseudomonas aeruginosa</i> infections. [PDF]

Antimicrob Agents Chemother
Collings H, Stone M, Chrysostomou M, Hirst A, Waldenberg TE, Yucel E, Iodise T.   +6 more
europepmc   +1 more source

Time Kill Curve PD Modelling Experiments Are Affected by Trailing MIC Endpoints: Refinement of MIC Determination for S. pseudintermedius

Journal of Veterinary Pharmacology and Therapeutics, Volume 49, Issue 2, Page 220-227, March 2026.
ABSTRACT Trailing endpoints are a recognised challenge in broth microdilution MIC testing, particularly for bacteriostatic agents such as trimethoprim (TMP) and sulphonamides. In this study, we applied a pharmacodynamically guided refinement to determine the MIC of the combination against Staphylococcus pseudintermedius; we did not aim at redefining ...
Andrew Mead, Ludovic Pelligand
wiley   +1 more source

Aminoglycosides: Activity and Resistance

Antimicrobial Agents and Chemotherapy, 1999
M. Mingeot-Leclercq, Y. Glupczynski, P. Tulkens   +2 more
semanticscholar   +1 more source

Bacterial lipid membranes as promising targets to fight antimicrobial resistance, molecular foundations and illustration through the renewal of aminoglycoside antibiotics and emergence of amphiphilic aminoglycosides

, 2016
M. Mingeot-Leclercq, J. Décout
semanticscholar   +1 more source

Designer aminoglycosides prevent cochlear hair cell loss and hearing loss.

Journal of Clinical Investigation, 2015
Markus E. Huth, Kyuhee Han, Kayvon Sotoudeh, Y. Hsieh, T. Effertz, Andrew A. Vu, Sarah Verhoeven, M. Hsieh, R. Greenhouse, A. Cheng, A. Ricci   +10 more
semanticscholar   +1 more source