Results 171 to 180 of about 69,960 (284)

Triple Threat: Elucidating Evolution Under Antibiotic, Metal, and Phage Pressure in Escherichia coli

Ecology and Evolution, Volume 16, Issue 9, September 2026.
Antibiotic resistance threatens treatment of bacterial infections, increasing research into alternative therapies, in particular whether new resistances will arise to these novel treatments. We evolved bacteria under phage, antibiotic, and heavy metal exposure.
Lindsey W. McGee, Noah K. Radtke, Gretchen S. Taylor, Joseph L. Graves Jr., Liesl Jeffers‐Francis   +4 more
wiley   +1 more source

Laboratory‐Detected Clostridioides difficile Stool‐Test Positivity and Mortality in Sepsis: A Retrospective Cohort Study

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Sepsis disrupts intestinal microbiota, and broad‐spectrum antibiotics may worsen dysbiosis. Clostridioides difficile (C. difficile) infection (CDI) is a prevalent nosocomial enteric pathogen among critically ill patients, yet its prognostic implications in sepsis remain inadequately studied.
Jiyun Hu, Fuxing Deng, Tingyue Hu, Binbin Meng, Songyun Deng, Lina Zhang, Wenchao Li   +6 more
wiley   +1 more source

Microbiome and resistome of the European bison (Bison bonasus). [PDF]

Sci Rep
Lechleiter N, Wedemeyer J, Junker J, Wilczek M, Klich D, Olech W, Anusz K, Homeier-Bachmann T, Didkowska A.   +8 more
europepmc   +1 more source

Treatment of central nervous system infections caused by <i>Pseudomonas aeruginosa</i> with difficult-to-treat resistance: a narrative review. [PDF]

Front Med (Lausanne)
Tao C, Hu Q.
europepmc   +1 more source

Volumetric Microsampling for Patient‐Centric Therapeutic Drug Monitoring in Clinical Pharmacology: A Scoping Review

The Journal of Clinical Pharmacology, Volume 66, Issue 9, September 2026.
Abstract Accurate drug concentration measurement is essential for precision pharmacotherapy, but conventional therapeutic drug monitoring (TDM) requires venous sampling, increasing patient burden, and potentially limiting participation in TDM and model‐informed precision dosing (MIPD).
Hari Prabhath Tummala, Abbie D. Leino, Nathaniel J. Rhodes, Kevin J. Downes, Marc H. Scheetz, Manjunath P. Pai   +5 more
wiley   +1 more source

Detecting Antibiotic Resistance in Strains of Selected Gram‐Negative Bacterial Species Using Raman Spectroscopy

Journal of Raman Spectroscopy, Volume 57, Issue 9, Page 1554-1564, September 2026.
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira, Adriano Moraes da Silva, Marcos Tadeu T. Pacheco, Landulfo Silveira Jr.   +3 more
wiley   +1 more source

Genome-wide network of antibiotic susceptibility in Pseudomonas aeruginosa. [PDF]

J Antimicrob Chemother
Goncalves O, Côté JP.
europepmc   +1 more source

A protein chaperone can stabilize the intein‐containing precursor to indirectly promote protein splicing

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Intervening proteins (inteins) interrupt host protein sequences and are removed by a self‐mediated protein splicing reaction. Inteins are abundant in the microbial world and are often found within essential genes involved in DNA replication, recombination, and repair.
John S. Smetana, Christopher R. Powell, Noy Bagdadi, Tia M. Ariagno, Hazel Thomas, Joel Weinberger II, Eyal Gur, Christopher W. Lennon   +7 more
wiley   +1 more source

Context-specific impact of antimicrobial stewardship on antibiotic use and antibiotic resistance in hospitals in a lower-middle-income country: results from an implementation study with a controlled interrupted time series design in Viet Nam. [PDF]

JAC Antimicrob Resist
Le QT, Vu TVD, Le MQ, Nguyen TTH, Vu HV, Chau MD, Vo THDE, Nguyen TCT, Truong AQ, Nguyen HK, Le NMH, Kesteman T, Dodds Ashley E, Anderson DJ, Turner HC, Pham NT, Cooper BS, Choisy M, van Doorn HR, Vu HTL.   +19 more
europepmc   +1 more source

Structural and functional insights into Pseudomonas aeruginosa ApaH, a diadenosine tetraphosphatase crucial for bacterial virulence

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Infections by Pseudomonas aeruginosa are a major cause of severe morbidity and mortality in immunocompromised patients and people with cystic fibrosis, largely due to the pathogen's ability to resist antibiotic treatment and to deploy multiple virulence strategies that promote persistence in the host.
Gianluca Pistoia, Matteo Cervoni, Flavia Catalano, Francesca Troilo, Francesca Guidi, Eleonora Comparini, Giuseppina Mignogna, Carlo Travaglini‐Allocatelli, Alessandro Giuffrè, Antonio Coluccia, Francesco Imperi, Adele Di Matteo, Giorgio Giardina   +12 more
wiley   +1 more source