Results 191 to 200 of about 66,693 (295)

Modulation of Quorum Sensing and Virulence Gene Expression in Escherichia coli by Extracts of Physalis alkekengi

Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Root extracts of Physalis alkekengi were examined for activity against multidrug‐resistant (MDR) Escherichia coli. The ethanolic extract suppressed bacterial growth, lowered biofilm formation by ~63%, and markedly reduced expression of luxS and fimH. Findings highlight P.
Mansoureh Esfandiyari Doolaby, Mohammad Javad Mehdipour Moghaddam, Akbar Norastehnia   +2 more
wiley   +1 more source

Multidrug-Resistant <i>Escherichia coli</i> Causing Respiratory and Systemic Infection in a Guinea Pig (<i>Cavia porcellus</i>) in Romania: A Case Report. [PDF]

Vet Sci
Gligor A, Iorgoni V, Nistor P, Popa SA, Popa I, Iancu I, Nichita I, Imre K, Tîrziu E, Herman V.   +9 more
europepmc   +1 more source

Aminoglycoside nephrotoxicity

Kidney International, 1988
openaire   +2 more sources

Multiple Mutations Lead to MexXY-OprM-Dependent Aminoglycoside Resistance in Clinical Strains of Pseudomonas aeruginosa [PDF]

, 2013
Sophie Guénard, Cédric Muller, Laura Monlezun, Philippe Bénas, Isabelle Broutin, Katy Jeannot, Patrick Plésiat   +6 more
openalex   +1 more source

Protective Effect of Vitamin E Against Vancomycin‐Induced Nephrotoxicity: A Large‐Scale Electronic Medical Record Study From Japan

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 6, June 2026.
ABSTRACT Vancomycin (VCM) is essential for treating methicillin‐resistant Staphylococcus aureus infections, but its use is limited by vancomycin‐induced nephrotoxicity (VIN). Although preclinical and small clinical studies suggest a protective role for vitamin E, real‐world evidence remains limited.
Satoru Nakanishi, Shungo Imai, Megumi Saito, Hayato Kizaki, Haru Iino, Masami Tsuchiya, Satoko Hori   +6 more
wiley   +1 more source

Identification of small molecules that enhance aminoglycoside-mediated suppression of <i>CFTR</i> and <i>NF1</i> nonsense mutations. [PDF]

Mol Ther Oncol
Sammons J, Chen J, Thrasher K, Fu L, Du M, Wen H, Bostwick JR, Vinson P, Moukha-Chafiq O, Augelli-Szafran C, Keeling KM, Wallis D, Kesterson RA, Rowe SM, Bedwell DM.   +14 more
europepmc   +1 more source

Characterization of Urinary Kidney Injury Biomarker Profiles in Healthy Japanese Subjects With Reference to a Counterpart US Study

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Drug‐induced kidney injury should be monitored throughout the drug development process to ensure patient safety. Standard kidney injury biomarkers may not always correlate with subtle microscopic histopathological kidney injury. Standard biomarkers are insufficiently sensitive for detection of early‐phase kidney injury.
Takehiko Sambe, Takuya Mizukami, Nicholas M. P. King, Gary Friedman, Stefan Sultana, Chieko Muto, Masanori Hizue, Yoichi Ii   +7 more
wiley   +1 more source

Changes in Susceptibility Profiles of <i>Acinetobacter baumannii</i> Clinical Isolates in a Multi-Profile Hospital in Years 2020-2024 in Lodz, Poland. [PDF]

J Clin Med
Bekier A, Bielec F, Grędysa M, Miaśkiewicz E, Nowak M, Pastuszak-Lewandoska D, Brauncajs M.   +6 more
europepmc   +1 more source

Discovery of two aminoglycoside antibiotics as inhibitors targeting the menin–mixed lineage leukaemia interface

, 2014
Lianchun Li, Ran Zhou, Heji Geng, Liyan Yue, Fei Ye, Yiqian Xie, Jing-Qiu Liu, Xiangqian Kong, Hualiang Jiang, Jian‐Dong Huang, Cheng Luo   +10 more
openalex   +1 more source

Integrative Genomics Identifies Candidate Genes Underlying Trypanotolerance in Hybrid African Cattle

Evolutionary Applications, Volume 19, Issue 6, June 2026.
ABSTRACT Integrative genomics combines data from different omics sources to link genotypes and phenotypes with the aim of unravelling biological networks and pathways that undergird complex traits, particularly with respect to disease. In this respect, integrative genomics, leveraging population and functional genomic data, can be employed to ...
Gillian P. McHugo, James A. Ward, Said Ismael Ng'ang'a, Laurent A. F. Frantz, John A. Browne, Michael Salter‐Townshend, Grace M. O'Gorman, Kieran G. Meade, Emmeline W. Hill, Thomas J. Hall, David E. MacHugh   +10 more
wiley   +1 more source