Results 211 to 220 of about 71,389 (251)

Antibiotic Resistance Genes in Salmonella Isolates from Food Production Environments and Clinical Sources in the Middle East: A Systematic Review and Meta-Analysis Revealing the Limited Comparative Genomic Evidence. [PDF]

Life (Basel)
Al-Hasan M, Al-Dhumair A, Al-Khalaifah H, Habibi N, Almatawah Q.   +4 more
europepmc   +1 more source

Validation of a Synthetic Wastewater Matrix as a Proxy for Municipal Wastewater for In Vitro Studies of E. coli

Environmental Microbiology Reports, Volume 18, Issue 5, October 2026.
In vitro studies of antimicrobial resistance (AMR) usually use rich laboratory media that differ from environmental conditions. We compared E. coli growth, antibiotic susceptibility and resistance development in LB broth, synthetic wastewater and autoclaved municipal wastewater. Both wastewaters restricted growth relative to LB and pH‐matched synthetic
Indorica Sutradhar, Neila Gross, Carly Ching, Yanina Nahum, Darash Desai, Devin A. Bowes, Muhammad H. Zaman   +6 more
wiley   +1 more source

Genome-wide network of antibiotic susceptibility in Pseudomonas aeruginosa. [PDF]

J Antimicrob Chemother
Goncalves O, Côté JP.
europepmc   +1 more source

Empirical Meropenem Versus Piperacillin/Tazobactam for Critically Ill Adults With Sepsis: Feasibility of a Randomised Trial

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 9, October 2026.
ABSTRACT Background Meropenem and piperacillin/tazobactam are commonly used empirical antibiotics in critically ill adults with sepsis, but whether one is superior to the other is uncertain. Methods The Empirical Meropenem versus Piperacillin/Tazobactam for Adult Patients with Sepsis (EMPRESS) trial is an ongoing investigator‐initiated, randomised ...
Nick Frørup Meier, Morten Hylander Møller, Maj‐Brit Nørregaard Kjær, Fredrik Sjövall, Marie Warrer Munch, Benjamin Skov Kaas‐Hansen, Hans‐Christian Thorsen‐Meyer, Bodil Steen Rasmussen, Marie Helleberg, Frederik Boëtius Hertz, Theis Lange, Aksel Karl Georg Jensen, Lars Wiuff Andersen, Jakob Steen Andersen, Jens Michelsen, Lars Peter Kloster Andersen, Morten Heiberg Bestle, Anne Craveiro Brøchner, Theis Skovsgaard Itenov, Steffen Christensen, Ronni Thermann Reitz Plovsing, Klaus Ulrik Koch, Anders Møller, Olav Lilleholt Schjørring, Naia Bech Cranø, Kasper Vamdrup‐Andersen, Davide Placido, Tine Sylvest Meyhoff, Carl Thomas Anthon, Aske Tøgern, Milda Grigonyte‐Daraskeviciene, Zemira Engbakken, Anne Witte Kamstrup, Kis Rønn Uhre, Jehad Ahmad Barakji, Rikke Faebo Larsen, Anders Perner, Anders Granholm   +37 more
wiley   +1 more source

Dequalinium chloride promotes the killing efficacy of aminoglycoside antibiotics against <i>Pseudomonas aeruginosa</i> by enhancing membrane potential. [PDF]

Microbiol Spectr
Wei X, Yang Z, Zhang Y, Xia X, Cheng Z, Jin Y, Jin S, Wu W.   +7 more
europepmc   +1 more source

Translational Prediction of Hemodialysis Clearance Integrating Molecular Structure and Dialysis Conditions

Clinical and Translational Science, Volume 19, Issue 10, October 2026.
Machine learning‐based prediction of hemodialysis clearance (CLHD) integrating molecular descriptors and dialysis conditions. XGBoost showed the best predictive performance, with lipophilicity as the most influential predictor. The model supports preliminary estimation of CLHD and assessment of drug dialyzability when empirical dialysis data are ...
Takahiko Aoyama, Tsukasa Kuwana, Atsushi Sato, Haruka Ohashi, Junko Yamaguchi, Toru Imai, Kosaku Kinoshita, Yasuhiro Tsuji   +7 more
wiley   +1 more source

Aminoglycosides induce immune activation but is insufficient for systemic viral control: a double-blind randomized-controlled clinical trial. [PDF]

Commun Med (Lond)
Sivanandam P, Syenina A, Chan YF, Ng DH, Gan ES, Yee JX, Tham CY, Tan HC, Ong EZ, Ooi EE, Kalimuddin S.   +10 more
europepmc   +1 more source

Genetic dissection reveals distinct contributions of the eS31 N‐terminal domain to translational accuracy in Saccharomyces cerevisiae

The FEBS Journal, Volume 293, Issue 20, Page 6076-6099, October 2026.
The eukaryote‐specific N‐terminal domain (NTD) of eS31 uses two distinct strategies to maintain translation fidelity. During elongation, a positively charged “hotspot” fine‐tunes the selection of incoming aa‐tRNA. During termination, the entire NTD acts as a structural scaffold to ensure the correct positioning of the release factor eRF1.
Qingxuan Gao, Hiroshi Otsuka, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Underprovision of Medical Compression Therapy: Retrospective Analysis Based on Statutory Health Insurance Data on Venous Leg Ulcers, Chronic Venous Disease and Comorbidities

International Wound Journal, Volume 23, Issue 10, October 2026.
ABSTRACT Chronic venous diseases (CVD), including venous leg ulcers (VLU), represent a significant health burden. Despite the central role of compression therapy in current treatment guidelines, recent evidence suggests substantial gaps in provision.
Markus Stücker, Eberhard Rabe, Kristina Hagenström, Tobias Hirsch, Luis Möckel, Kristin Sauer   +5 more
wiley   +1 more source

Context-specific impact of antimicrobial stewardship on antibiotic use and antibiotic resistance in hospitals in a lower-middle-income country: results from an implementation study with a controlled interrupted time series design in Viet Nam. [PDF]

JAC Antimicrob Resist
Le QT, Vu TVD, Le MQ, Nguyen TTH, Vu HV, Chau MD, Vo THDE, Nguyen TCT, Truong AQ, Nguyen HK, Le NMH, Kesteman T, Dodds Ashley E, Anderson DJ, Turner HC, Pham NT, Cooper BS, Choisy M, van Doorn HR, Vu HTL.   +19 more
europepmc   +1 more source