Results 71 to 80 of about 6,130 (209)

Saffron Alters Microbial Amino Acid Metabolism and Neurotransmitter Production in a Defined Gut Consortium

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Graphical representation of the metabolic pathways modulated by saffron within defined microbial communities. In the tryptophan pathway, saffron decreased levels of tryptophan and anthranilic acid while increasing concentrations of indole‐3‐acetic acid and tryptamine.
Adelaide E. Horvath, Makenna Grozis, Paul R. S. Baker, Santosh Kapil Kumar Gorti, Robert Proos, Ahmad Imran, Hassan Brim, Thomas D. Horvath, Melinda A. Engevik, Hassan Ashktorab   +9 more
wiley   +1 more source

Front line defenders of the ecological niche! Screening the structural diversity of peptaibiotics from saprotrophic and fungicolous Trichoderma/Hypocrea species [PDF]

, 2014
Approximately 950 individual sequences of nonribosomally biosynthesised peptides are produced by the genus Trichoderma/Hypocreathat belong to a perpetually growing class of mostly linear antibiotic oligopeptides, which are rich in the non-proteinogenic α-
Brückner, Hans, Degenkolb, Thomas, Iversen, Anita, Jaklitsch, Walter Michael, Nielsen, Kristian Fog, Röhrich, Christian René, Thrane, Ulf, Vilcinskas, Andreas, Voglmayr, Hermann, von Döhren, Hans   +9 more
core   +3 more sources

Analyzing Nicotine Action Against Amyloid Toxicity by NMR‐Pharmacometabolomics: An Exploratory Study

NMR in Biomedicine, Volume 39, Issue 4, April 2026.
Combined metabolomic analysis of the intracellular and extracellular portions of SH‐SY5Y cells revealed that, in the presence of Aβ 1–42, nicotine primarily influences pathways related to neurotransmission, energy metabolism, as well as the biosynthesis and degradation of membrane phospholipids.
Enza Napolitano, Carmen Marino, Manuela Grimaldi, Michela Buonocore, Angelo Santoro, Anna Maria D'Ursi   +5 more
wiley   +1 more source

Measuring blood–brain barrier dysfunction: a critical appraisal of fluid biomarkers, in vitro models, in vivo imaging, and post‐mortem approaches

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract The blood–brain barrier (BBB) maintains central nervous system homeostasis by regulating molecular exchange between blood and brain. BBB dysfunction is associated with aging and neurological disorders such as Alzheimer's disease, stroke, and multiple sclerosis.
Shakira A. van der Panne, Helena Durrant, Jannis F. Heuer, Ivana Kancheva, Arno Stellingwerf, Lieuwe T. K. M. Verkaar, Damon Verstappen, Pascalle Mossel, Walter H. Backes, Erik N. T. P. Bakker, Jurgen A. H. R. Claassen, Marcel M. Verbeek, Louise van der Weerd, Matthias J. P. van Osch, Helga E. de Vries   +14 more
wiley   +1 more source

The muscle–intervertebral disc interaction mediated by L-BAIBA modulates extracellular matrix homeostasis and PANoptosis in nucleus pulposus cells

Experimental and Molecular Medicine
Upon engaging in physical activity, skeletal muscle synthesizes myokines, which not only facilitate crosstalk with various organs, including the brain, adipose tissue, bone, liver, gut, pancreas, and skin but also promote intramuscular signaling ...
Tianyu Qin, Ming Shi, Chao Zhang, Jiajun Wu, Zhengqi Huang, Xiaohe Zhang, Shuangxing Li, Yuliang Wu, Weitao Han, Bo Gao, Kang Xu, Song Jin, Wei Ye   +12 more
doaj   +1 more source

Integrated Metabolome and Microbiome Analysis Reveals the Regulatory Effects of Fermented Soybean Meal on the Gut Microbiota of Late Gestation

Fermentation
Late gestation is a critical period for regulating maternal peripartum physiological metabolism and gut microbiota balance. Fermented diets have been widely recognized as effective exogenous nutritional interventions capable of modulating the maintenance
Yantao Li, Lele Fu, Yushi Chen, Hua Yang, Yingping Xiao, Ying Ren, Cheng Wang   +6 more
doaj   +1 more source

Nutrition and Aromatic Components Analysis and Antioxidant Activity Evaluation of Gu Nin Chio Banana(Gu Nin Chio香蕉果实营养、香气成分分析及抗氧化活性评价) [PDF]

Shipin kexue jishu xuebao
To clarify the nutritional value, aromatic composition and anti oxidation activity of a newly introduced Gu Nin Chio banana in China, spectrophotometry, HPLC(high-performance liquid chromatography), ICP-MS (inductively coupled plasma-mass spectrometry ...
TAN Lin(谭琳), LI Sunjin(李孙锦), LIU Xingdi(刘兴地), LI Jingyang(李敬阳), CHEN Qingmian(陈清勉)   +4 more
doaj   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, Volume 22, Issue 16, 17 March 2026.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Enviromimetics: From exercise mimetics to cognitomimetics in the quest for enhanced brain health and cognition

The Journal of Physiology, Volume 604, Issue 6, Page 2458-2472, 15 March 2026.
Abstract figure legend A schematic diagram outlining the concept of enviromimetics, and the subclasses of exercise mimetics, epimimetics and cognitomimetics. The rationale is that environmental stimulation and lifestyle factors, including physical activity and cognitive stimulation, have shown beneficial effects across a range of human conditions ...
Anthony J. Hannan
wiley   +1 more source

Searching for Extraterrestrial Amino Acids in a Contaminated Meteorite: Amino Acid Analyses of the Canakkale L6 Chondrite [PDF]

Amino acids can serve as important markers of cosmochemistry, as their abundances and isomeric and isotopic compositions have been found to vary predictably with changes in parent body chemistry and alteration processes.
Burton, A. S., Dworkin, J. P., Elsila, J. E., Esenoglu, H. H., Glavin, D. P., Ornek, C. Y., Ozturk, B., Unsalan, O.   +7 more
core   +1 more source