Results 111 to 120 of about 61,455 (226)

A Reproducible Workflow for Macrophage Membrane Isolation and Nanocore Selection Toward Bioinspired Nanoparticles Targeting Immunologically Cold Tumors

Small Methods, Volume 10, Issue 5, 9 March 2026.
A reproducible workflow is established for isolating macrophage membranes to enable the efficient preparation and characterization of membrane‐coated nanoparticles. By optimizing M2‐like nanovesicle stability and nanocore compatibility, this procedure advances the engineering of macrophage membrane‐coated nanoparticles with improved tumor targeting ...
Diana Peixoto, Patricia Diaz‐Rodriguez, Francisco Veiga, Angel Concheiro, Ana Cláudia Paiva‐Santos, João Conde, Carmen Alvarez‐Lorenzo   +6 more
wiley   +1 more source

EPR of Co(II) as a Structural and Mechanistic Probe of Metalloprotein Active Sites: A Review of Studies on Aminopeptidase [PDF]

, 2002
Co(II) can often be substituted for Zn(II) in zinc-dependent metalloenzymes to provide spectroscopically accessible forms of the enzymes. Co(II) is an excellent spectroscopic probe as it is both optically active and EPR active.
Bennett, Brian
core   +1 more source

Enhanced below‐ground functioning is associated with higher plant resistance against drought: Implications for ecosystem functions

Journal of Ecology, Volume 114, Issue 3, March 2026.
The results suggest that the subordinate species achieves higher drought resistance in biomass and soil functions via increased below‐ground functioning. The data presented here provide a basis to explain the underlying mechanisms behind the response of grassland communities and their C cycling to drought.
Alberto Canarini, Pierre Mariotte, Yolima Carrillo, Raúl Ochoa‐Hueso, Jeremy Bougoure, Sotirios Vasileiadis, Ian C. Anderson, Feike A. Dijkstra, Andreas Richter, Hirokazu Toju, Erica Donner, Sally A. Power, Barbara Drigo   +12 more
wiley   +1 more source

Analyzing the Catalytic Role of Asp97 in the Methionine Aminopeptidase from \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]

, 2008
An active site aspartate residue, Asp97, in the methionine aminopeptidase (MetAPs) from Escherichia coli (EcMetAP-I) was mutated to alanine, glutamate, and asparagine.
Bennett, Brian, Holz, Richard C., Job, Kathleen M., Meng, Lu, Mitra, Sanghamitra   +4 more
core   +1 more source

Multi‐Omics Reveals Phenethyl Acetate and Its Producer Lactiplantibacillus plantarum as Key Drivers of Enhanced Palatability in Alfalfa Silage

Microbial Biotechnology, Volume 19, Issue 3, March 2026.
The quality and flavour profile of silage affect its palatability and the feed intake of ruminants. This study offers a novel strategy for optimising the synergistic fermentation of Lactiplantibacillus plantarum and phenylethyl acetate, thereby enhancing alfalfa silage flavour quality and promoting sheep feed intake.
Zhihui Fu, Tianwei Wang, Jiaqi Zhang, Wenzhao Wang, Xiumin Zhang, Kaixuan Wei, Muhammad Tahir, Jin Zhong   +7 more
wiley   +1 more source

Editorial: Physiological, Pathological Roles and Pharmacology of Insulin Regulated Aminopeptidase

Frontiers in Molecular Biosciences, 2021
Siew Yeen Chai, Hugo Gutiérrez-de-Terán, Efstratios Stratikos   +2 more
doaj   +1 more source

Clathrins Are Involved in the Endocytosis of Host Cytosol in the Malaria Parasite

Traffic, Volume 27, Issue 1, March 2026.
This study characterized clathrin function in hemoglobin uptake from host red blood cells via the malaria parasite's specific endocytosis machinery, cytostome. Clathrin heavy chain, clathrin light chain, and AP‐1 γ subunit were found associated with certain proteins known to be involved in cytostome function, and they were localized at the collars of ...
Jun Miao, Amuza Byaruhanga Lucky, Gang Ning, Xian Xia, Xiaoying Liang, Faiza Siddiqui, Hui Min, Chengqi Wang, Xiaolian Li, Z. Hong Zhou, Liwang Cui   +10 more
wiley   +1 more source

Effect of ultrasonication and use of aminopeptidase from Aeromonas proteolytica on quality parameters of fish protein hydrolysates from side streams of Atlantic mackerel (Scomber scombrus)

Frontiers in Nutrition
In the present study, both ultrasonication (US) and enzymatic treatment with aminopeptidase from Aeromonas proteolytica (AAP) were applied as a post-treatment to fish protein hydrolysates (FPH) recovered from Atlantic mackerel.
Janna Cropotova, Kristine Kvangarsnes, Janne Stangeland, Amélie Le Gall, Turid Rustad   +4 more
doaj   +1 more source

EPR Studies on the Mono- and Dicobalt(II)-Substituted Forms of the Aminopeptidase from \u3cem\u3eAeromonas proteolytica\u3c/em\u3e. Insight into the Catalytic Mechanism of Dinuclear Hydrolases [PDF]

, 1997
The structure and function of the prototypical dinuclear hydrolase, namely, the aminopeptidase from Aeromonas proteolytica (AAP), was probed by EPR spectroscopy of the mono- and dicobalt(II)-substituted derivatives.
Bennett, Brian, Holz, Richard C.
core   +1 more source

Chemoproteomics validates selective targeting of Plasmodium M1 alanyl aminopeptidase as an antimalarial strategy

eLife
New antimalarial drug candidates that act via novel mechanisms are urgently needed to combat malaria drug resistance. Here, we describe the multi-omic chemical validation of Plasmodium M1 alanyl metalloaminopeptidase as an attractive drug target using ...
Carlo Giannangelo, Matthew P Challis, Ghizal Siddiqui, Rebecca Edgar, Tess R Malcolm, Chaille T Webb, Nyssa Drinkwater, Natalie Vinh, Christopher Macraild, Natalie Counihan, Sandra Duffy, Sergio Wittlin, Shane M Devine, Vicky M Avery, Tania De Koning-Ward, Peter Scammells, Sheena McGowan, Darren J Creek   +17 more
doaj   +1 more source