Results 91 to 100 of about 1,233 (154)

Editorial: Physiological, Pathological Roles and Pharmacology of Insulin Regulated Aminopeptidase

Frontiers in Molecular Biosciences, 2021
Siew Yeen Chai, Hugo Gutiérrez-de-Terán, Efstratios Stratikos   +2 more
doaj   +1 more source

Effect of ultrasonication and use of aminopeptidase from Aeromonas proteolytica on quality parameters of fish protein hydrolysates from side streams of Atlantic mackerel (Scomber scombrus)

Frontiers in Nutrition
In the present study, both ultrasonication (US) and enzymatic treatment with aminopeptidase from Aeromonas proteolytica (AAP) were applied as a post-treatment to fish protein hydrolysates (FPH) recovered from Atlantic mackerel.
Janna Cropotova, Kristine Kvangarsnes, Janne Stangeland, Amélie Le Gall, Turid Rustad   +4 more
doaj   +1 more source

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

The FEBS Journal, Volume 293, Issue 13, Page 3758-3787, July 2026.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka, Matija Hrovatin, Bor Bokalj, Boris Turk   +3 more
wiley   +1 more source

Proteolytic remodelling of the extracellular matrix by pericytes

The FEBS Journal, Volume 293, Issue 13, Page 3899-3953, July 2026.
Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard, Ella Milne, Kate Qian, Paola Campagnolo, Salvatore Santamaria   +4 more
wiley   +1 more source

Biochar and Sediment Amendments Alter Soil Nitrogen Mineralization: Microbial Biomass and Extracellular Enzyme Activity

GCB Bioenergy, Volume 18, Issue 7, July 2026.
Co‐application of Mn‐modified biochar and fishpond sediment markedly improves soil pH, organic carbon, microbial biomass, and nitrogen mineralization, demonstrating a synergistic effect that enhances soil fertility, microbial activity, and nutrient cycling for sustainable agricultural management.
Waqas Ahmed, Yunting Wang, Sajid Mehmood, Sehrish Ali, Fengyue Qin, Lun Tan, Weidong Li, Md Ashraful Alam   +7 more
wiley   +1 more source

Chemoproteomics validates selective targeting of Plasmodium M1 alanyl aminopeptidase as an antimalarial strategy

eLife
New antimalarial drug candidates that act via novel mechanisms are urgently needed to combat malaria drug resistance. Here, we describe the multi-omic chemical validation of Plasmodium M1 alanyl metalloaminopeptidase as an attractive drug target using ...
Carlo Giannangelo, Matthew P Challis, Ghizal Siddiqui, Rebecca Edgar, Tess R Malcolm, Chaille T Webb, Nyssa Drinkwater, Natalie Vinh, Christopher Macraild, Natalie Counihan, Sandra Duffy, Sergio Wittlin, Shane M Devine, Vicky M Avery, Tania De Koning-Ward, Peter Scammells, Sheena McGowan, Darren J Creek   +17 more
doaj   +1 more source

Tolerance to Phosphorus Deficiency Improves Seed Phytic Acid‐to‐Iron Molar Ratios in Common Bean

Plant, Cell &Environment, Volume 49, Issue 7, Page 4152-4165, July 2026.
ABSTRACT Although significant advances have been achieved in the biofortification of common beans to overcome deficiencies in Zinc (Zn) and iron (Fe), the mechanisms involved remain poorly understood. We thus explored the relationships between phosphorus nutrition and Zn and Fe accumulation in four bean genotypes (Edar, Nizok, Colorado and Chimbolos ...
Barbara Karpinska, Christine H. Foyer
wiley   +1 more source

Zinc-dependent aminopeptidases: new perspectives on structure, function, and biomedical applications

Frontiers in Chemical Biology
Zinc-dependent aminopeptidases are a subclass of exopeptidases implicated in the hydrolysis of N-terminal residues from peptides through a Zn(II) co-factor dependent hydrolytic mechanism. In humans, the prominent members of this class of enzymes (ERAP1/2,
Saleem Bhat
doaj   +1 more source

Rapid CO2 effects on protein‐related metabolism during photosynthetic gas exchange

The Plant Journal, Volume 127, Issue 1, July 2026.
SUMMARY It is common practice to vary atmospheric CO2 mole fraction (Ca) during gas exchange experiments to manipulate photorespiration and explore photosynthetic properties such as maximum carboxylation velocity. In doing so, it is assumed that changing Ca essentially alters the carboxylation‐to‐oxygenation ratio, with negligible effects on other ...
Corentin Dourmap, Cyril Abadie, Marlène Davanture, Willy Bienvenut, Julie Lalande, Guillaume Tcherkez   +5 more
wiley   +1 more source

CIA5 and its interacting metal‐binding GTPase ZNG3 are degraded by the proteasome in Zn deficiency

The Plant Journal, Volume 127, Issue 1, July 2026.
SUMMARY Carbon and zinc (Zn) metabolism are tightly connected in phototrophs, as carbonic anhydrases critical for CO2 assimilation are highly abundant Zn enzymes. The eukaryotic green alga Chlamydomonas (Chlamydomonas reinhardtii) maintains efficient phototrophic growth in ambient or low CO2 environments by establishing a carbon concentrating mechanism
George Kusi‐Appiah, Stefan Schmollinger, Andrew Mamo, Sarah C. Stainbrook, Thomas V. O'Halloran, Daniela Strenkert   +5 more
wiley   +1 more source