Results 91 to 100 of about 40,140 (225)

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

Insect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto, Andrew A. Walker, Glenn F. King   +2 more
wiley   +1 more source

Diagnostic Biomarkers of Periodontitis and Peri‐Implantitis: The Past, the Present, the Future

Journal of Periodontal Research, EarlyView.
Diagnostic biomarkers of periodontitis and peri‐implantititis from the past, through the present, and into the future. ABSTRACT In this narrative review we present our perspective on the past, present and future of periodontal and peri‐implantitis diagnostic biomarkers.
Denis F. Kinane, Başak Bıyıkoğlu
wiley   +1 more source

Pharmacological Targets for Periodontitis: A Systematic Review of Drug‐Target Mendelian Randomisation Studies

Journal of Periodontal Research, EarlyView.
This systematic review evaluated drug‐target Mendelian randomisation studies on periodontitis. Twelve studies identified host‐response‐related targets mainly involved in inflammatory, complement, and immune pathways. Although some targets were linked to existing drugs, the evidence remains preliminary and heterogeneous, requiring replication and ...
Luigi Nibali, Jing Kang, Simon Haworth, Alessandro Polizzi, Gaetano Isola   +4 more
wiley   +1 more source

Inhibition of Aminopeptidase I

, 1978
The inhibition of aminopeptidase I from Eschericia coli K12 by several dipeptides, which are not hydrolyzed by the enzyme, has been examined quantitatively. The dissociation constants (K,) of three of these inhibitors with the enzyme have been determined.
Cabilio, Juta
core  

Persulfidome of Sweet Pepper Fruits during Ripening: The Case Study of Leucine Aminopeptidase That Is Positively Modulated by H₂S

Antioxidants
Protein persulfidation is a thiol-based oxidative posttranslational modification (oxiPTM) that involves the modification of susceptible cysteine thiol groups present in peptides and proteins through hydrogen sulfide (H2S), thus affecting their function ...
María A. Muñoz-Vargas, Salvador González-Gordo, Angeles Aroca, Luis C. Romero, Cecilia Gotor, José M. Palma, Francisco J. Corpas   +6 more
doaj   +1 more source

Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia

Journal of Neuroinflammation, 2012
Background Cerebral inflammation is a hallmark of neuronal degeneration. Dipeptidyl peptidase IV, aminopeptidase N as well as the dipeptidyl peptidases II, 8 and 9 and cytosolic alanyl-aminopeptidase are involved in the regulation of autoimmunity and ...
Röhnert Peter, Schmidt Werner, Emmerlich Patrick, Goihl Alexander, Wrenger Sabine, Bank Ute, Nordhoff Karsten, Täger Michael, Ansorge Siegfried, Reinhold Dirk, Striggow Frank   +10 more
doaj   +1 more source

Biomarkers Correlating With the Development of Oral Squamous Cell Carcinoma From Leukoplakia

Oral Diseases, EarlyView.
ABSTRACT Background We assessed protein biomarkers expressed in oral leukoplakia (OL) that are associated with the risk of transformation into oral squamous cell carcinoma (OSCC). Methods Tissue sections of OL transforming into OSCC (leuko‐ca), the corresponding OSCC and OL that did not progress to OSCC (leuko‐nonca) were analyzed with global relative ...
Daniel Giglio, Divya Ganesh, Bishwa Prakash Bhattarai, Tine Merete Søland, Jonas Sundberg, Annika Thorsell, Jenny Öhman, Dipak Sapkota, Bengt Hasséus   +8 more
wiley   +1 more source

Beneath the Drought: Rhizosphere Processes Shape Genotype‐Specific Sorghum Responses to Drought‐Induced N Limitation

Plant, Cell &Environment, EarlyView.
ABSTRACT Droughts increasingly threaten crop productivity in nutrient‐depleted tropical soils. We investigated how water limitation influences rhizomicrobial traits (microbial biomass and functional community composition, enzyme activities) and nitrogen (N) uptake in three sorghum genotypes Makueni local (Mkl), Gadam (Gd), and IESH 22012 (IESH) under ...
Rosepiah Munene, Osman Mustafa, Sara Loftus, Vincent O. Suba, Nipuna Withanage, Niklas Schmücker, Peter Bulli, Reimund P. Rötter, Dennis O. Otieno, Mutez A. Ahmed, Michaela A. Dippold   +10 more
wiley   +1 more source

Methionine aminopeptidase associated with liver mitochondria and microsomes

, 1981
A new, unstable, particle-bound (particularly mitochondria and microsomes) aminopeptidase, mol. wt 74,000, was partially purified from rat liver. Among five aminoacyl-β-naphthylamides assayed, MetNA was the best substrate. The aminopeptidase releases NH2-
Prado, J. L. [UNIFESP], Termignoni, C. [UNIFESP], Borges, D. R. [UNIFESP], Guimarães, J. A., Freitas, J. O. [UNIFESP], Sampaio, CAM [UNIFESP]   +5 more
core   +1 more source

Microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases

Periodontology 2000, EarlyView.
Abstract Objectives To critically evaluate the current evidence on microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases, with emphasis on their biological relevance, potential clinical utility, and current translational limitations.
Su Sheng Quach, Ausra Ramanauskaite, Sašo Ivanovski, Pingping Han, Frank Schwarz, Emilio A. Cafferata   +5 more
wiley   +1 more source