Results 71 to 80 of about 61,885 (239)

X-ray Crystallographic Characterization of the Co(II)-substituted Tris-bound Form of the Aminopeptidase from \u3cem\u3eAeromonas proteolytica\u3c/em\u3e [PDF]

, 2007
The X-ray crystal structure of the Co(II)-loaded form of the aminopeptidase from Aeromonas proteolytica ([CoCo(AAP)]) was solved to 2.2 Å resolution. [CoCo(AAP)] folds into an α/β globular domain with a twisted β-sheet hydrophobic core sandwiched between
Bennett, Brian, Holz, Richard C., Moulin, Aaron, Munih, Petra, Petsko, Gregory A., Ringe, Dagmar, Stamper, Carin   +6 more
core   +1 more source

The Silent Link: Exploring the Impact of Periodontal Diseases on Head and Neck Carcinogenesis

Clinical and Experimental Dental Research, Volume 12, Issue 3, June 2026.
ABSTRACT Objectives Oral dysbiosis can accelerate the progression of head and neck squamous cell carcinoma (HNSCC) by fostering a pro‐inflammatory, immunosuppressive, and metabolically altered environment. This narrative review examines the relationships between periodontitis‐associated bacteria and HNSCC, focusing on their impact on oncogenic pathways,
Yashmin Afshar, Nima Rezaei
wiley   +1 more source

Onset of transcription of the aminopeptidase N (leukemia antigen CD 13) gene at the crypt/villus transition zone during rabbit enterocyte differentiation [PDF]

, 1932
The sequence of a cDNA clone (2.82 kbp) of rabbit intestinal aminopeptidase N (CD 13) is reported. Using the corresponding anti-sense RNA probe, the distribution of aminopeptidase N mRNA along the crypt/villus axis of the rabbit small intestine was ...
O. Norén, E. Dabelsteen, P.E. Høyer, J. Olsen, H. Sjöström, G.H. Hansen, Gordon, Noré, Semenza, Semenza, Nordströ, Skovbjerg, Danielsen, Webster, Weiser, Lojda, Olsen, Look, Watt, Olsen, Look, Kruse, Hunziker, Henikoff, Sanger, Biggin, Deeley, Maniatis, Angerer, Rentrop, Feracci, McCaman, Foglino, Jongeneel, Rehfeld, Bronstein, Boller, Danielsen   +37 more
core   +1 more source

Successful in vitro propagation of feline coronavirus from clinically diagnosed feline infectious peritonitis cases using Vero cells: A potential model for future research

Veterinary Record Open, Volume 13, Issue 1, June 2026.
Abstract Background Feline coronavirus (FCoV) causes inapparent to progressive fatal feline infectious peritonitis (FIP) in domestic and wild cats, which affects multiple‐organ systems. Methods We investigated three clinically sick cats using different laboratory and molecular tests to diagnose and confirm FCoV and propagate the virus in Vero cell ...
Eaftekhar Ahmed Rana, Mahfuza Akther, Susan Beetson, Subir Sarker, Gabriele Rossi, Jasim M. Uddin   +5 more
wiley   +1 more source

Spectroscopically Distinct Cobalt(II) Sites in Heterodimetallic Forms of the Aminopeptidase from \u3cem\u3eAeromonas proteolytica\u3c/em\u3e:  Characterization of Substrate Binding [PDF]

, 1997
The Co(II)Zn(II)- and Zn(II)Co(II)-substituted derivatives of the aminopeptidase from Aeromonas proteolytica (AAP) were probed by EPR spectroscopy. EPR spectra of the high-spin S = 3/2 Co(II) ions in [CoZn(AAP)] and [ZnCo(AAP)] indicated that each metal ...
Bennett, Brian, Holz, Richard C.
core   +1 more source

Aminopeptidase C of Aspergillus niger is a Novel Phenylalanine Aminopeptidase [PDF]

, 2003
A novel enzyme with a specific phenylalanine aminopeptidase activity (ApsC) from Aspergillus niger (CBS 120.49) has been characterized. The derived amino acid sequence is not similar to any previously characterized aminopeptidase sequence but does share ...
Basten, E.J.W., Dekker, P.J.T., Schaap, P.J.   +2 more
core   +2 more sources

Changes in DOM Quality Determine Prokaryotic Activities and Extracellular Release in the NW Mediterranean Sea: An Experimental Approach

Environmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Changes in DOM composition influence prokaryotic species growth in the Mediterranean Sea, shaping their metabolic responses and organic matter processing. In our study, higher DOP consumption and alkaline phosphatase activity led to the accumulation of recalcitrant DOM, highlighting how microbial community shifts drive distinct pathways in carbon ...
Eva Ortega‐Retuerta, Nawal Bouchachi, Rebeca Campos, Olivier Crispi, Barbara Marie, Charles‐Hubert Paulin, Karine Escoubeyrou, Jonathan Colombet, Telesphore Sime‐Ngando, Anabel Von Jackowski   +9 more
wiley   +1 more source

Divalent Metal Binding Properties of the Methionyl Aminopeptidase from \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]

, 2000
The metal-binding properties of the methionyl aminopeptidase from Escherichia coli (MetAP) were investigated. Measurements of catalytic activity as a function of added Co(II) and Fe(II) revealed that maximal enzymatic activity is observed after the ...
Bennett, Brian, Copik, Alicja J., D\u27Souza, Ventris M., Holz, Richard C.   +3 more
core   +1 more source

Positioning of Melflufen in Heavily Pretreated RRMM Patients: Real‐World Evidence in a Rapidly Evolving Therapeutic Landscape

European Journal of Haematology, Volume 116, Issue 6, Page 928-936, June 2026.
ABSTRACT Modern therapies have clearly marked the history of multiple myeloma (MM), leading to undisputed advantages in terms of sustained responses and prolonged survival, while progressively improving patients' quality of life. Nonetheless, disease recurrence and resistance to available therapies underscore the importance of identifying additional ...
K. Mancuso, S. Masci, M. Talarico, A. Vitale, S. Barbato, V. Solli, M. Puppi, I. Rizzello, L. Pantani, P. Tacchetti, M. Iezza, R. Restuccia, I. Sacchetti, E. Manzato, S. Ghibellini, S. Armuzzi, B. Taurisano, M. Cavo, E. Zamagni   +18 more
wiley   +1 more source

Polymorphic positions 349 and 725 of the autoimmunity-protective allotype 10 of ER aminopeptidase 1 are key in determining its unique enzymatic properties

Frontiers in Immunology
IntroductionER aminopeptidase 1 (ERAP1) is a polymorphic intracellular aminopeptidase with key roles in antigen presentation and adaptive immune responses.
Galateia Georgaki, Galateia Georgaki, Anastasia Mpakali, Anastasia Mpakali, Myrto Trakada, Athanasios Papakyriakou, Efstratios Stratikos, Efstratios Stratikos   +7 more
doaj   +1 more source