Results 91 to 100 of about 9,870 (205)

Mucus glycoproteins selectively secreted from bacteriocytes in gill filaments of the deep-sea clam Calyptogena okutanii [PDF]

, 2013
The deep-sea clam Calyptogena okutanii possesses a large gill containing vertically transmitted symbiotic sul-fur-oxidizing bacteria. It produces large amounts of highly viscoelastic mucus from the gill, which is thought to be a physical and chemical ...
FUJIKURA, Katsunori, FUJISHIMA, Masahiro, HATADA, Yuji, KONISHI, Masaaki, KUSAKA, Chiho, MARUYAMA, Tadashi, NAKAMURA, Yoshimitsu, NAKAZAWA, Masatoshi, OHISHI, Kazue, TAME, Akihiro, YOSHIDA, Takao, 中村, 欽光, 中澤, 正年, 丸山, 正, 吉田, 尊雄, 多米, 晃裕, 大石, 和恵, 小西, 正朗, 日下, 智保, 秦田, 勇二, 藤倉, 克則, 藤島, 政博   +21 more
core   +1 more source

Targeting cancer metabolism: a therapeutic window opens [PDF]

, 2011
Genetic events in cancer activate signalling pathways that alter cell metabolism. Clinical evidence has linked cell metabolism with cancer outcomes. Together, these observations have raised interest in targeting metabolic enzymes for cancer therapy, but ...
A Clementi, A Dimitrakopoulou-Strauss, A Garten, A Le, A Wolf, A Yalcin, AM Groves, AP Halestrap, AP Pereira da Silva, AS Marsin, B Clem, B Dwarakanath, BA Chabner, BK Mohanti, BR Landau, C Algire, C Derst, C Garcia-Echeverria, C Yang, CH Holdsworth, CM Murray, CS Potten, CV Dang, D Hanahan, D Singh, DA Rew, DA Tennant, DA Tennant, DE Bauer, DK Nomura, DR Wise, DW Parsons, E Eschwege, E Furuta, ED Michelakis, EE Calle, EE Calle, ER Mardis, ES Burgos, G Hatzivassiliou, G Marcucci, G Ollenschlager, GA Spoden, GL Semenza, H Linardou, H Shim, H Yan, HA Hirsch, HR Christofk, HR Christofk, I Maestu, I Papandreou, J Kurhanewicz, J Luo, J Yun, JA Engelman, JA Engelman, JA Menendez, JA Meyerhardt, Jason W Locasale, JB Wang, JD Broome, JG Kidd, JK Jiang, JM Brown, JM Evans, JW Kim, JW Locasale, K Brindle, K Chen, K Duvel, K Holen, K Hosono, K Zaugg, KE Wellen, KH Vousden, KM Kennedy, KS Dimmer, L Dang, L Galluzzi, L Tallal, LG Boros, M Buzzai, M Hasmann, M Ko, M Ookhtens, M Pittelli, M Pollak, M Pollak, M Tahiliani, M Takenaka, M Yuneva, MA Weiser, Matthew G. Vander Heiden, MB Boxer, MB Tessem, MC Li, ME Figueroa, MG Vander Heiden, MG Vander Heiden, MG Vander Heiden, MJ Evans, MJ Holness, MJ Ovens, MJ Seltzer, ML Macheda, ML Tainter, MR Stratton, MS Ardawi, MY El-Mir, N El Mjiyad, N Jaffe, N Normanno, NP Curthoys, NP Manes, NY Kalaany, O Kaplan, P Cocco, P Gao, P Sonveaux, P Thirion, PS Ward, R Chowdhury, R Flavin, R Zhou, R Zoncu, RA Cairns, RA Larson, RB Robey, RB Scott, RE Neuman, RG Jones, RG Maki, RG Verhaak, Richard Possemato, RJ Deberardinis, RJ DeBerardinis, RJ Shaw, RJ Shaw, RL Aft, RM Memmott, S Ben-Haim, S Bonnet, S Bruzzone, S Farber, S Farber, S Gross, S Jiralerspong, S Mazurek, S Stacchiotti, S Telang, SH Jee, SJ Bach, SL Bowker, SM Gallagher, SP Mathupala, T Atsumi, T Cheng, T Shlomi, T Yamamoto, TS Yang, V Chajes, VR Fantin, VT DeVita, W Hu, W Kuo, W Xu, WG Kaelin Jr, Y Kumei, Y Ni, Y Yu, YH Ko   +171 more
core   +1 more source

Preparation of Monoclonal Antibody to Vasorin in Tree Shrew and Exploration of Its Application

Shiyan dongwu yu bijiao yixue
ObjectiveTo obtain tree shrew Vasorin (VASN) recombinant protein through prokaryotic expression and purification, prepare monoclonal antibody against tree shrew VASN by immunizing mice with this protein, and preliminarily evaluate its application value ...
OU Meizhen, LI Yongfeng, WEN Sha, LIAO Zhouxiang, HUANG Xuejing, YANG Lichao, HE Min   +6 more
doaj   +1 more source

Update on therapeutic approaches for rheumatoid arthritis [PDF]

, 2016
Rheumatoid arthritis is a common chronic inflammatory and destructive arthropathy that consumes considerable personal, social and economic costs.
Cavaco-Paulo, Artur, Gomes, Andreia, Nogueira, Eugenia, Preto, Ana   +3 more
core   +1 more source

Early signaling defects in human T cells anergized by T cell presentation of autoantigen. [PDF]

, 1992
Major histocompatibility complex class II-positive human T cell clones are nontraditional antigen-presenting cells (APCs) that are able to simultaneously present and respond to peptide or degraded antigen, but are unable to process intact protein ...
Freeman, GJ, Hafler, DA, LaSalle, JM, Nadler, LM, Tolentino, PJ   +4 more
core  

Role of CD4 epitopes outside the gp120-binding site during entry of human immunodeficiency virus type 1 [PDF]

, 1997
CD4 is the primary receptor for human immunodeficiency virus (HIV). The binding site for the surface glycoprotein of HIV type 1 (HIV-1), gp120, has been mapped to the C'-C" region of domain 1 of CD4. Previously, we have shown that a mutant of rat CD4, in
Simon, J.H.M, Stumbles, P.A., Signoret, N., Somoza, C., Puklavec, M., Sattentau, Q.J., Barclay, A.N., James, W.   +7 more
core   +1 more source

DHFR Inhibitors Display a Pleiotropic Anti-viral Activity Against SARS-CoV-2: Insights Into the Mechanisms of Action [PDF]

Viruses, 2023
Iaconis D, Caccuri F, Manelfi C, Talarico C, Bugatti A, Filippini F, Zani A, Novelli R, Kuzikov M, Ellinger B, Gribbon P, Riecken K, Esposito F, Corona A, Tramontano E, Beccari AR, Caruso A, Allegretti M.   +17 more
europepmc   +2 more sources

Computational and Experimental Drug Repurposing of FDA-Approved Compounds Targeting the Cannabinoid Receptor CB1. [PDF]

Pharmaceuticals (Basel), 2023
Criscuolo E, De Sciscio ML, De Cristofaro A, Nicoara C, Maccarrone M, Fezza F.   +5 more
europepmc   +1 more source

Adoptive T Cell Therapy for Metastatic Colorectal Cancer [PDF]

, 2013
Colorectal cancer is the second leading cause of cancer-related death in US (1). Most of the mortality reflects local, regional and distant metastatic tumors.
Ebanks, Shauna
core   +1 more source

Aminopterin [PDF]

, 2020
openaire   +1 more source