Results 71 to 80 of about 9,870 (205)

Immunoassay Detection of SARS‐CoV‐2 Using Monoclonal Antibody Binding to Viral Nucleocapsid Protein

Microbial Biotechnology, Volume 18, Issue 2, February 2025.
Selective detection of SARS‐CoV viral variants by immunoassay with monoclonal antibodies (MAbs) 4D4 and 1H6 that bind nucleocapsid protein (NP). Sensitive detection of SARS‐CoV‐2 NP and SARS‐CoV‐2 virus variants by sandwich ELISA (left) and lateral flow immunoassay (right).
Robert M. Hnasko, Alice V. Lin, Jeffery A. McGarvey, Eric S. Jackson   +3 more
wiley   +1 more source

Impact of bidirectional relationships between streptococcus anginosus group and host tissue matrix components on cellular activity: Role in establishment of infection [PDF]

, 2003
This paper investigates pathogenic mechanisms of the Streptococcus anginosus group (SAG) of bacteria which influence the biological activity of periodontal ligament (PDL) cells, endothelial cells and also how matrix proteins produced by these host cells ...
Waddington, Rachel J., Landrygan-Bakri, Janine, Wilson, Melanie, Williams, David W., Lewis, Michael Alexander Oxenham   +4 more
core   +10 more sources

Impact of Methotrexate and 7‐Hydroxymethotrexate Exposure on Renal Toxicity in Pediatric Non‐Hodgkin Lymphoma

Cancer Medicine, Volume 14, Issue 2, January 2025.
ABSTRACT Background 7‐Hydroxymethotrexate (7‐OHMTX) is the main metabolite in plasma following high‐dose MTX (HD‐MTX), which may result in activity and toxicity of the MTX. Moreover, 7‐OHMTX could produce crystalline‐like deposits within the renal tubules under acidic conditions or induce renal inflammation, oxidative stress, and cell apoptosis through
Hao Bing, Yi Ma, Jiamin Xu, Qixian Ling, Yanlong Duan, Libo Zhao   +5 more
wiley   +1 more source

Introduction and Expression of a Rabbit β-globin Gene in Mouse Fibroblasts [PDF]

, 1979
The cloned chromosomal rabbit ß-globin gene has been introduced into mouse fibroblasts by DNA-mediated gene transfer (transformation). In this report, we examine the expression of the rabbit gene in six independent transformants that contain from 1 to 20
Axel, R., Lacy, E., Maniatis, T., Silverstein, S., Wigler, M., Wold, B.   +5 more
core  

Cell surface localization of tissue transglutaminase is dependent on a fibronectin-binding site in its N-terminal beta-sandwich domain [PDF]

, 1999
Increasing evidence indicates that tissue transglutaminase (tTG) plays a role in the assembly and remodeling of extracellular matrices and promotes cell adhesion.
Aeschlimann, D, Cox, A, Gaudry, CA, Griffin, M, Smith, C, Verderio, E   +5 more
core   +1 more source

Cunning Pathogen Tactics: Neutrophil Movement Influenced by Bacterial Attractants in the Experimental Model

Cellular Microbiology, Volume 2025, Issue 1, 2025.
To explore the peculiarities of neutrophil motility, two models of chemoattraction were created: a horizontal model, where a container with bacterial chemoattractant was attached laterally to the endotheliocyte monolayer, and a vertical model, simulating a pyemic focus in the lower part of the modified Boyden chamber.
Svetlana N. Pleskova, Nikolay А. Bezrukov, Ekaterina N. Gorshkova, Eseniya V. Otstavnova, Dmitry V. Novikov, Suraiya Saleem   +5 more
wiley   +1 more source

Epidemiology of neural tube defects in northern Iran, 1998-2003 [PDF]

, 2007
We determined the rates of neural tube defects at a referral hospital in Gorgan, north Islamic Republic of Iran, and the relations of these abnormalities to sex, maternal ethnicity, maternal age and season.
Golalipour, M.J., Keshtkar, A.A., Mobasheri, E., Vakili, M.A.   +3 more
core  

Construction of two whole genome radiation hybrid panels for dromedary (Camelus dromedarius): 5000RAD and 15000RAD [PDF]

, 2018
The availability of genomic resources including linkage information for camelids has been very limited. Here, we describe the construction of a set of two radiation hybrid (RH) panels (5000RAD and 15000RAD) for the dromedary (Camelus dromedarius) as a ...
Alshanbari, F, Brooks, S A, Burger, P A, Gaggl, A, Holl, H M, Larkin, D M, Perelman, P L, Periasamy, K, Pichler, R, Raudsepp, T   +9 more
core   +3 more sources

Combating Methotrexate Resistance in Cancer Treatment: A Review on Navigating Pathways and Enhancing Its Efficacy With Fat‐Soluble Vitamins

Scientifica, Volume 2025, Issue 1, 2025.
Methotrexate (MTX), a potent analogue and antagonist of folic acid, is a first‐line treatment for rheumatoid arthritis, IBD and cancer. The development of MTX resistance contributes to the reduced efficacy and development of adverse reactions, forcing clinicians to withdraw treatment early.
Muhsina Kakkadath, Disha Naidu, S. K. Kanthlal, Khan Sharun, Raghuram Kandimalla   +4 more
wiley   +1 more source

Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecretory tissue. [PDF]

, 1981
Two different monoclonal antibodies, characterized initially as binding synaptic terminal regions of rat brain, bind a 65,000-dalton protein, which is exposed on the outer surface of brain synaptic vesicles. Immunocytochemical experiments at the electron
Matthew, WD, Reichardt, LF, Tsavaler, L
core   +2 more sources