Results 51 to 60 of about 6,112 (161)

Drug‐Tolerant, Chemiluminescent Lateral Flow Immunoassay Platform for the Determination of Neutralizing Anti‐Drug Antibodies

Small, Volume 21, Issue 40, October 9, 2025.
Immunogenicity evaluation in patients receiving mAb therapy is becoming the standard of care in healthcare systems worldwide. Nevertheless, current methods for anti‐drug antibody determination suffer from drug interference and/or inability to be performed at the point‐of‐care (POC).
Frans Kokojka, Ron Ramon, Sigal Pressman, Yehuda Chowers, Robert S. Marks   +4 more
wiley   +1 more source

A Scoping Review of Human Teratogens and Their Impact on the Developing Brain: A Contribution From the ConcePTION Project

Birth Defects Research, Volume 117, Issue 9, September 2025.
ABSTRACT Certain medications, when used during pregnancy, are known to impact human prenatal development. Historically, little attention has been given to the impact of in utero exposure on the developing brain, despite the significance of known teratogen‐induced neurodevelopmental difficulties.
M. Bluett‐Duncan, J. Adams, M. Berkovitch, M. Berlin, A. Cahoon, J. Clayton‐Smith, C. Jackson, S. Khanom, D. Mølgaard‐Nielsen, J. L. Richardson, V. Simms, M. Stellfeld, U. Winterfeld, L. M. Yates, R. L. Bromley   +14 more
wiley   +1 more source

Twenty Years of the Paediatric Radiation Oncology Society

Pediatric Blood &Cancer, Volume 72, Issue 7, July 2025.
ABSTRACT In 2005, the Paediatric Radiation Oncology Society (PROS), a multi‐professional association to promote radiotherapy for children and young people, was created. Its mission has been to educate those involved in this field, and to improve the standards of radiation oncology care for children, adolescents, and young adults across the globe, not ...
Mark N. Gaze, Guillaume Beldjoudi, Christian Carrie, Carolyn Freeman, Daniel J. Indelicato, Rolf‐Dieter Kortmann, Ingrid Kristensen, Anne Laprie, Yasmin Lassen, Anita Mahajan, Karen J. Marcus, Pauline Njoki Njiraini, Jeannette Parkes, Arnold C. Paulino, Bilal Mazhar Qureshi, Beatriz García Robles, Klaus Seiersen, Beate Timmermann, Natia Esiashvili   +18 more
wiley   +1 more source

Evolution of Therapy in Pediatric ALL From Aminopterin to Chimeric Antigen Receptor T-Cell Therapy: Global Advances, Indian Adaptations, and Lessons for Low- and Middle-Income Countries

JCO Global Oncology
PURPOSESurvival outcomes for childhood ALL in low- and middle-income countries (LMICs) have shown gradual improvement, closely following the remarkable outcomes achieved in high-income countries, albeit with some time lag.
Debabrata Mohapatra, Jagdish Prasad Meena, Aditya Kumar Gupta, Rachna Seth   +3 more
doaj   +1 more source

Heterohybridomas producing human immunoglobulin light chains using CD138-selected bone marrow cells

Biochemistry and Biophysics Reports
Background: Light chain research is hampered by lack of mammalian cell lines producing human light chains (FLC). Therefore, we used heterohybridoma (HH) technology to produce clones making FLC thereby providing tools to study light chain behavior ...
P. Zhou, X. Ma, S. Scalia, D. Toskic, X. Wu, T. Fogaren, Nancy Coady Lyons, Luis del Pozo-Yauner, R.L. Comenzo   +8 more
doaj   +1 more source

Preparation of Monoclonal Antibody to Vasorin in Tree Shrew and Exploration of Its Application

Shiyan dongwu yu bijiao yixue
ObjectiveTo obtain tree shrew Vasorin (VASN) recombinant protein through prokaryotic expression and purification, prepare monoclonal antibody against tree shrew VASN by immunizing mice with this protein, and preliminarily evaluate its application value ...
OU Meizhen, LI Yongfeng, WEN Sha, LIAO Zhouxiang, HUANG Xuejing, YANG Lichao, HE Min   +6 more
doaj   +1 more source

Computational and Experimental Drug Repurposing of FDA-Approved Compounds Targeting the Cannabinoid Receptor CB1. [PDF]

Pharmaceuticals (Basel), 2023
Criscuolo E, De Sciscio ML, De Cristofaro A, Nicoara C, Maccarrone M, Fezza F.   +5 more
europepmc   +1 more source

Aminopterin [PDF]

, 2020
openaire   +1 more source

DHFR Inhibitors Display a Pleiotropic Anti-viral Activity Against SARS-CoV-2: Insights Into the Mechanisms of Action [PDF]

Viruses, 2023
Iaconis D, Caccuri F, Manelfi C, Talarico C, Bugatti A, Filippini F, Zani A, Novelli R, Kuzikov M, Ellinger B, Gribbon P, Riecken K, Esposito F, Corona A, Tramontano E, Beccari AR, Caruso A, Allegretti M.   +17 more
europepmc   +2 more sources

Aminopterin in the Treatment of Acute Leukaemia [PDF]

BMJ, 1950
J V, DACIE, E, DRESNER, D L, MOLLIN, J C, WHITE   +3 more
openaire   +2 more sources