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Application of Metabolomics in Carcinogenesis and Cancer Prevention by Dietary Phytochemicals. [PDF]
Curr Pharmacol RepPeter RM, Su X, Kong AN.
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[Acute leukemia and aminopterin].
Boletin medico del Hospital Infantil de Mexico, 2004 openaire +1 more source
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An aminopterin‐like syndrome without aminopterin (ASSAS)
Clinical Genetics, 1987In two patients that closely resembled the phenotype of the syndrome produced by aminopterin in early pregnancy, no evidence of maternal exposure could be elicited. These, plus two similar cases from the literature, suggest the existence of an “aminopterin‐like syndrome sine aminopterin” (ASSA) syndrome.
F C, Fraser +3 more
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Archives of Dermatology, 1955
Aminopterin (4-a m i n o-pteroylglutamic acid) is a potentially dangerous drug. It can favorably affect the lesions of psoriasis regularly, but the range between beneficial and toxic doses is narrow. The possibility of irreversible bone marrow aplasia is of chief concern in toxicity.
R B, REES, J H, BENNETT, W L, BOSTICK
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Aminopterin (4-a m i n o-pteroylglutamic acid) is a potentially dangerous drug. It can favorably affect the lesions of psoriasis regularly, but the range between beneficial and toxic doses is narrow. The possibility of irreversible bone marrow aplasia is of chief concern in toxicity.
R B, REES, J H, BENNETT, W L, BOSTICK
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Maternal Aminopterin Ingestion
Archives of Pediatrics & Adolescent Medicine, 1973To the Editor. —We read with interest the case report by E. B. Shaw, MD: "Fetal Damage Due to Maternal Aminopterin Ingestion: Follow-Up at Age 9 Years," as well as the editorial comment by Dr. Warkany (Am J Dis Child124:93-94, 1972). We suspect that the patient's apparently good current mental development and the mildness of the earlier mental defect ...
M L, Netzloff, J L, Frias, O M, Rennert
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The photodecomposition of aminopterin
Journal of Immunological Methods, 1987Aminopterin is used in cell fusion experiments to select for hybrid cells by killing unfused cells which are deficient in enzymes for nucleotide salvage pathways. Aqueous aminopterin solutions exposed to fluorescent room light (wavelength greater than 300 nm) were found to lose cytotoxicity.
P F, Fehlner +3 more
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Further case of aminopterin syndrome sine aminopterin in a Spanish child
American Journal of Medical Genetics, 2000We report on a Spanish child with clinical manifestations suggestive of aminopterin syndrome sine aminopterin (ASSA), having unusual hair pattern, syndactyly of fingers and toes, low-set thumbs, high-arched palate, and mild developmental delay. However, he does not show other characteristic features of ASSA such as ossification defects of the cranium ...
S, Garcia-Minaur, M P, Botella
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Archives of Dermatology, 1964
Antifolics are rational for psoriasis. Normal renal clearance is of vital importance; this may be true of normal liver functions as well. No fatal or near fatal reactions occurred in our series. We have reviewed two deaths following aminopterin (Aminopterin Sodium) therapy, apparently from inadequate renal clearance, one severe reaction for the same ...
R B, REES +3 more
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Antifolics are rational for psoriasis. Normal renal clearance is of vital importance; this may be true of normal liver functions as well. No fatal or near fatal reactions occurred in our series. We have reviewed two deaths following aminopterin (Aminopterin Sodium) therapy, apparently from inadequate renal clearance, one severe reaction for the same ...
R B, REES +3 more
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Caenorhabditis briggsae: Effects of aminopterin
Experimental Parasitology, 1974Abstract The characteristic features of senescence developed prematurely in Caenorhabditis briggsae treated with the DNA synthesis inhibitor aminopterin at the minimum dosage which inhibits gonad formation. In addition, aminopterin induced other changes which thus far have not been associated with normal aging of C. briggsae .
M J, Kisiel +2 more
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Methotrexate vs. Aminopterin for Psoriasis
Archives of Dermatology, 1961The value of antimetabolites for psoriasis was first observed by Gubner. 1 He pointed out that the suppressive effects of aminopterin were much greater on epithelium than on blood-forming organs. Aminopterin (4-aminopteroylglutamic acid) is a metabolically useless analogue of folic acid.
R B, REES, J H, BENNETT
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