Effects of tacrine, aminopyridines, and physostigmine on acetylcholinesterase, acetylcholine release, and potassium currents [PDF]
This article discusses the effects of tacrine, aminopyridines, and physostigmine on acetylcholinesterase, acetylcholine release, and potassium ...
Harvey, Alan L., Rowan, E.G.
core
Copper-catalyzed domino sequences: a new route to pyrido-fused quinazolinones from 2′-haloacetophenones and 2-aminopyridines [PDF]
A new pathway to access pyrido-fused quinazolinones via a Cu(OAc)2-catalyzed domino sequential transformation between 2′-haloacetophenones and 2-aminopyridines was demonstrated.
Nam T. S. Phan +11 more
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Characteristics of weak base-induced vacuoles formed around individual acidic organelles
We have previously found that the weak base 4-aminopyridine induces Brownian motion of acidic organelles around which vacuoles are formed, causing organelle traffic disorder in neurons.
Tadashi Kawakami, Hiromi Hiruma
doaj +1 more source
New conjugates of amiridine and salicylimine/amine with an N‐acylalkylene spacer were synthesized. N‐acylation of amiridine conjugates leads to a decrease in their protonation, resulting in a substantial reduction in anticholinesterase activity and relative inability to block Aβ42 self‐aggregation compared to previously studied analogs with an N ...
Galina F. Makhaeva +14 more
wiley +1 more source
Aminopyridines block an inactivating potassium current having slow recovery kinetics [PDF]
The blocking action of aminopyridines on an inactivating K current (lKi) in GH3 pituitary cells was studied before and after altering the macroscopic decay of the current with N-bromoacetamide (NBA).
Oxford, G.S. +3 more
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CuBr catalyzed aerobic oxidative coupling of 2-aminopyridines with cinnamaldehydes: direct access to 3-formyl-2-phenyl-imidazo[1,2-a]pyridines [PDF]
Copper bromide catalyzed aerobic oxidative coupling of 2-aminopyridines with cinnamaldehydes directly led to the formation of 3-formyl-2-phenyl-imidazo[1,2-a]pyridines.
Bharate, Sandip B. +4 more
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Review: Current treatment of vestibular, ocular motor disorders and nystagmus
Vertigo and dizziness are among the most common complaints with a lifetime prevalence of about 30%. The various forms of vestibular disorders can be treated with pharmacological therapy, physical therapy, psychotherapeutic measures or, rarely, surgery ...
Michael Strupp, Thomas Brandt
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Infrared and raman spectroscopic investigations of cadmium tetracyanonickelate complexes of aminopyridines [PDF]
The infrared and Raman spectra of three new complexes of the formula CdL2Ni(CN)4 {L = 2-aminopyridine or 2-amino-4-methylpyridine} and Cd(L) (NH3)-Ni(CN)4 {L = 2-amino-3-methylpyridine} are reported.
AKYÜZ, SEVİM
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η6-Coordination catalysis has emerged as an effective strategy for activating electron-rich (hetero)arenes toward nucleophilic substitution. Recent experimental studies on Ru(II)-catalyzed amination of aminopyridines revealed a striking ortho–para ...
Cheng Wang, Shuo-Qing Zhang, Xin Hong
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Synthesis of Heavily Substituted 2-Aminopyridines by Displacement of a 6-Methylsulfinyl Group [PDF]
2-Aminopyridines, with a variety of polar 6-substituents, were elaborated by displacement of a methylsulfinyl group from the 6-position of the pyridine ring.
Simon J. Teague (1840519)
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