Results 1 to 10 of about 1,525 (139)

Non-Alcoholic Steatohepatitis Decreases Microsomal Liver Function in the Absence of Fibrosis [PDF]

open access: yesBiomedicines, 2020
The incidence of non-alcoholic fatty liver disease (NAFLD) is rising across the globe, with the presence of steatohepatitis leading to a more aggressive clinical course.
Wim Verlinden   +12 more
doaj   +2 more sources

Elucidating VOC dynamics and molecular mechanisms in nonanal-treated postharvest tomatoes infected with Botrytis cinerea [PDF]

open access: yesFood Chemistry: Molecular Sciences
In this study, an 0.054 mol·L−1 nonanal treatment decreased the incidence rate of gray mold on tomato and enhanced the defense capacity by altering the activities of the main defense-related enzymes, including NADPH-cytochrome c reductase, aminopyrine-n ...
Hongdou Gao   +11 more
doaj   +2 more sources

Validated RP-HPLC-UV Method for Simultaneous Quantification of Aminophenazone, Dipyrine, and Chlorpheniramine Maleate in Pharmaceutical Formulations Considering Dipyrine Decomposition [PDF]

open access: yesInternational Journal of Analytical Chemistry
Aminophenazone, dipyrine, and chlorpheniramine maleate combined drug is used as antipyrine and analgesic. In this study, a rapid, robust, and straightforward high-performance liquid chromatographic (HPLC) technique was developed, optimized, and validated
Md. Abid Hasan   +5 more
doaj   +2 more sources

Effects of electroacupuncture on treatment-resistant chronic migraine with medication overuse headache: A 12-month follow-up case report [PDF]

open access: yesHeliyon
Background: Medication overuse headache (MOH) is a secondary headache disorder that leads to pronounced disability and decreased quality of life. Available therapeutic options for MOH are limited, and many are only effective in a subset of individuals ...
Ning Gao   +6 more
doaj   +2 more sources

In vivo effects of Faizol Ubat Batuk, a herbal product on aminopyrine metabolism in rat hepatocytes [PDF]

open access: yesLibyan Journal of Medicine, 2011
Traditional medicines, in particular herbal products, have been used abundantly over the years in curing several diseases. Pharmacological interactions of herbal products with modern drugs, however, remain to some extent unknown.
Abas Hj Hussin, Yousef A. Taher
doaj   +1 more source

Enhanced HBsAg synthesis correlates with increased severity of fibrosis in chronic hepatitis B patients. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND AND AIMS: Little is known about whether low serum HBsAg levels result from impaired HBsAg synthesis or a reduced number of hepatocytes caused by advanced liver fibrosis.
Mei-Zhu Hong   +6 more
doaj   +1 more source

Clearance tests as a diagnosis method of hepatobiliary system pathologies in animals

open access: yesАграрная наука Евро-Северо-Востока, 2023
In present-day conditions of industrial agriculture, the animal's body works at the limit of its capabilities, which leads to degenerative diseases of various organs and systems.
V. S. Ponamarev   +3 more
doaj   +1 more source

Substrate Specificity of Human Cytochrome P450 (CYP) 2C Subfamily and Effect of Azole Antifungal Agents on CYP2C8

open access: yesJournal of Pharmacy & Pharmaceutical Sciences, 2016
PURPOSE: The metabolic activities of aminopyrine N-demethylation and tolbutamide methylhydroxylation by the human hepatic cytochrome P450 (P450 or CYP) 2C subfamily were compared and the effects of azole antifungal agent on the drug-metabolizing activity
Toshiro Niwa, Yurie Imagawa
doaj   +1 more source

Exploration of a high-performance liquid chromatography method for antibiotic drug monitoring in melioidosis patients and establishment of its sampling procedure

open access: yesResults in Chemistry, 2023
Purpose: To establish a high-performance liquid chromatography (HPLC) method that simultaneously monitors the concentrations of sulfamethoxazole (SMZ) and trimethoprim (TMP) in the plasma of patients with melioidosis during the intensive or eradication ...
Xiangxiang Fu   +7 more
doaj   +1 more source

Benzobarbital and fluorbenzobarbital - hepatic monooxygenase system phenobarbital-like inducers

open access: yesБюллетень сибирской медицины, 2011
Benzobarbital and fluorbenzobarbital as monooxygenase system inductors increase the hepatic cytochrome P-450 level and the content of its isoenzymes 2B6, 2C9, 2Å1, accelerate aminopyrine, 7-ethoxyresorufine, 7-pentoxyresorufine, aniline and ...
T. P. Novozheyeva   +3 more
doaj   +1 more source

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