EFFECT OF THE ORTHOSIPHON STAMINEUS, BENTH ON AMINOPYRINE METABOLISM IN RAT HEPATOCYTES [PDF]
One of the commonly used herbal medicines in Malaysia is Orthosiphon stamineus, Benth (family: Lamiaceae) or locally known as Misai Kucing. This experiment was undertaken to evaluate possible interaction of methanol extract of O.
CHIN JIN HAN1, ABAS HJ. HUSSIN
doaj +2 more sources
Analysis of Illicit Street Heroin Seized in Pakistan by Gas Chromatography-Mass Spectrometry (GC-MS) for Identification of Adulterants and Impurities. [PDF]
Heroin abuse poses a significant public health and law enforcement challenge globally, with concerns in Pakistan due to the prevalence of illicit street heroin and limited data on its composition. This study analyzed 706 heroin samples seized between 2017 and 2022 using gas chromatography–mass spectrometry (GC‐MS) and Fourier transform infrared ...
Usman M +4 more
europepmc +2 more sources
<i>Hibiscus rosa-sinensis</i>: A Multifunctional Flower Bridging Nutrition, Medicine, and Molecular Therapeutics. [PDF]
H. rosa‐sinensis bioactives modulate oxidative and inflammatory pathways. Myricetin and rutin show strong α‐glucosidase and SOD binding affinity. Exhibits safe, multifunctional use in health, food and nutraceuticals. ABSTRACT Hibiscus rosa‐sinensis, commonly known as the shoe flower, thrives in tropical and subtropical regions across South China, Asia,
Raza H +6 more
europepmc +2 more sources
Breath by Breath: Navigating the Landscape of Exhaled Breath in Clinical Research and Prospects for the Future. [PDF]
Exhaled breath analysis (EBA) has evolved as a noninvasive diagnostic technique with enormous promise in healthcare. The development in this area is based on the concept that the breathalyzers employed to measure the alcohol concentration in the blood can be utilized to evaluate health by analyzing the intricate chemical makeup of exhaled breath, which
Parikh N +10 more
europepmc +2 more sources
Analgesic and Antidiarrheal Properties of Lappaconitine, Possibly Through Cyclooxygenase and µ-Opioid Receptor Interaction Pathways: In Vivo and In Silico Studies. [PDF]
ABSTRACT Background Lappaconitine (LAP) is a diterpenoid alkaloid with strong anti‐inflammatory activity. However, there is limited information on its gastroprotective effects. The present study aimed to explore the analgesic and antidiarrheal effects of LAP through in vivo and in silico studies.
Shah S +11 more
europepmc +2 more sources
Aminopyrine accumulation by mammalian gastric glands: an analysis of the technique [PDF]
Isolated gastric glands from rabbits and parietal cells from dogs have recently become useful in studying the control and enzymatic mechanisms of gastric H+ secretion.
J. Sack, J. G. Spenney
core +1 more source
Aminopyrine metabolism in cryopreserved isolated rat hepatocytes [PDF]
The method to preserve isolated rat hepatocytes under cryogenic conditions (−70 °C) is described. Aminopyrine N-demethylase activity in the frozen–thawed cells was 10–50% that of freshly prepared hepatocytes and was dependent on the storage time.
W. A. Mahon +6 more
core +1 more source
Developing an ultrasensitive immunochromatographic assay for authentication of an emergent fraud aminopyrine in herbal tea [PDF]
Aminopyrine is a nonsteroidal anti-inflammatory drug only for medical purposes, however, it has been illegally added in traditional Chinese herbal teas for fraud activity recently.
Koidis, Anastasios; id_orcid +10 more
core +1 more source
Background. In the management of chronic hepatitis C (CHC) patients, liver biopsy is the gold standard for liver fibrosis assessment despite some technical limits and risks.
Gian Paolo Caviglia +8 more
doaj +1 more source
Pharmacology and relevant drug interactions of metamizole. [PDF]
Metamizole is a frequently prescribed analgesic because of its favourable benefit/risk ratio compared with classic NSAIDs. However, increasing research shows that metamizole displays several drug interactions that are relevant to clinical practice. We reviewed the literature to summarize the pharmacology and most clinically relevant drug interactions ...
Brinkman DJ +3 more
europepmc +2 more sources

