Gastroenterology Research and Practice, 2017 Assessment of the liver function, and the need of constant monitoring of the organ’s capacity, concerns not only patients with primary liver diseases, but also those at risk of hepatopathies secondary to other chronic diseases.
Katarzyna Gorowska-Kowolik +2 more
doaj +1 more source
Nitric oxide-an endogenous inhibitor of gastric acid secretion in isolated human gastric glands
BMC Gastroenterology, 2004 Background Endothelial nitric oxide synthase (eNOS) has previously been detected in the glandular part of the human gastric mucosa. Furthermore, nitric oxide (NO) has been shown to influence gastric secretion in various animal models.
Ericson Ann-Charlott +3 more
doaj +1 more source
Gastrin and carbachol require cAMP to elicit aminopyrine accumulation in isolated pig and rat parietal cells [PDF]
, 1995 The role of endogenous adenosine 3',5'-cyclic monophosphate (cAMP) in the mechanisms of action of gastrin and carbachol on aminopyrine accumulation in isolated pig and rat parietal cells was investigated.
J. L. Cabero, Z. Q. Li, S. Mardh
core +1 more source
Diabetes in female rats; changes in liver microsomal aminopyrine N-demethylase and UDP-glucuronyl transferase activities [PDF]
, 1990 Short or long term diabetes in female rats produced remarkable activation of aminopyrine N-demethylation, inhibition of oestrone and p-nitrophenol glucuronidation and no changes in morphine UDP-glucuronyltransferase activity in vitro.
Villar, Eugenia del +7 more
core +1 more source
Alteration in Metabolism and Toxicity of Acetaminophen Upon Repeated Administration in Rats
Journal of Pharmacological Sciences, 2009 Our previous studies showed that administration of a subtoxic dose of acetaminophen (APAP) to female rats increased generation of carbon monoxide from dichloromethane, a metabolic reaction catalyzed mainly by cytochrome P450 (CYP) 2E1.
Sun J. Kim +4 more
doaj +1 more source
Effect of fasting on the toxicity and serum concentration of aminopyrine in rats [PDF]
, 1970 The acute oral toxicity of aminopyrine is considerably greater in the fasted rat than in the fed rat. Acute toxicity by the ip route was comparable in these two groups of animals.
Nelson, John M. +2 more
core +1 more source
Detection of Serum Antibodies to Aminopyrine or its Derivatives by a Passive Hemagglutination Assay Method [PDF]
, 1970 1970-03An attempt has been made to detect antibodies to aminopyrine or its derivatives (pyrazolone derivatives) with a passive hemagglutination assay system.
KAMIYA, OSAMU +3 more
core +1 more source
Effect of aging on healing of mandibular tooth extraction socket in a rat model
European Journal of Oral Sciences, EarlyView.Abstract This study evaluated the effect of aging on bone regeneration in mandibular extraction sockets. Male Sprague–Dawley rats were divided into three age groups: 2‐month‐old (2 M, n = 6), 10‐month‐old (10 M, n = 6), and 18‐month‐old (18 M, n = 5). Two weeks post‐extraction, comprehensive analyses were performed using micro‐computed tomography (µ‐CT)
Kyung Su Shin +7 more
wiley +1 more source
Harnessing Free Radical Scavenging Potential of Caffeic Acid as a Nutraceutical—A Review
Food Safety and Health, Volume 4, Issue 2, Page 327-342, April 2026.Caffeic acid has emerged as a promising bioactive molecule with multiple pharmacological properties, including antioxidant, antimicrobial, anti‐inflammatory, organ protective properties and metal‐chelating ability. This review emphasizes the dietary sources, structural characteristic, molecular mechanism underlying health promoting effects of caffeic ...
Pavitra Behra +2 more
wiley +1 more source
Renal aminopyrine demethylation in several species determined by a sensitive radiometric method [PDF]
, 1984 Renal microsomal aminopyrine demethylation activities of several species were measured by a sensitive radiometric method using [dimethylamino-14C-]aminopyrine as a substrate and 2,4-dinitrophenylhydrazine as a trapping agent for the formaldehyde formed ...
Yoshihito Omori +5 more
core +1 more source