Results 71 to 80 of about 4,774 (193)
A Solubility Comparison of Neutral and Zwitterionic Polymorphs
Several amphoteric model compounds and drugs, such as isomers of aminobenzoic acids (ortho, meta, and para), N-aryl-2-amino-nicotinic acids (three isomers), amino-salicylic acids (meta and para), clonixin, and niflumic acid, were selected to obtain their
Ashwini Nangia (1400761) +1 more
core +1 more source
We report on the detailed NMR spectral analyses of amino- or/and hydroxy-substituted benzoic acids: anthranilic (AA), 3-hydroxyanthranilic (3-HAA), 5-hydroxyanthranilic (5-HAA), salicylic (SA), 4-aminosalicylic (4-ASA) and 5-aminosalicylic (5-ASA) acids.
Miltojević, Ana B., Radulović, Niko S.
core
5-ASA decreases colonic sulfide formation: implications for ulcerative colitis.
Experimental evidence suggests that anionic sulfide (SH-) may be implicated in the pathogenesis of ulcerative colitis. Sulfides are formed in the colon by sulfate-reducing bacteria acting on sulfate or sulfur amino acids.
Roediger, W., Duncan, A.
core
The ability of 5-aminosalicylic acid (5-ASA) to be oxidized to a quinone monoimine compound capable of conjugating with nucleophilic compounds such as N-acetyl-cysteine (NAC) and glutathione (GSH) has been investigated in vitro. Three isomeric conjugates
Tjornelund, J. +4 more
core
Steroids and 5-aminosalicylic acids in moderate ulcerative colitis: addressing the dilemma. [PDF]
Probert C.
europepmc +1 more source
Synthesis, in-vitro bioactivity evaluation and molecular docking of monosaccharide ester and fatty acid amide derivatives of 5-aminosalicylic acid [PDF]
5-aminosalicylic acid (5-ASA), structurally related to the salicylates, is active in the treatment of inflammatory bowel disease (IBD). Since IBD is a high-incidence disease and considering that 5-ASA has been approved as one of the most effective and ...
Yousefi, Samira
core
This report describes a rapid, single-run procedure, based on the optimization of capillary electrophoresis (CE) and indirect absorbance detection capabilities, which was developed for the separation and quantification of 30 underivatized physiological ...
Zunić, G +3 more
core
Presenting Symptom: Ataxia; Photophobia; Scotoma; Ischemia; Aura. Anatomy: Orbit; Retina; Serotonin. Disease/Diagnosis: Migraine disorders; Migraine with aura.
Alfredo A. Sadun, MD, PhD
core
Synthesis, Structural Characterization, and In Silico Evaluation of the Salicylidene Schiff Base 4‑{(<i>E</i>)‑[(2,3-Dihydroxyphenyl)methylidene]amino}-2-hydroxybenzoic Acid as a Promising Scaffold for Human Transthyretin Inhibitor. [PDF]
Nowak P, Sikorski A.
europepmc +1 more source

