Results 1 to 10 of about 5,991,558 (223)

Comparison of effects of aminosalicylic acid, glucocorticoids and immunosuppressive agents on the expression of multidrug-resistant genes in ulcerative colitis [PDF]

Scientific Reports, 2022
To compare the effects of aminosalicylic acid, glucocorticoids and immunosuppressants on the expression levels of multidrug resistance genes in patients with ulcerative colitis (UC), with the aim of providing a theoretical and therapeutic basis for the ...
Yan Chen, Ping Wang, Yin Zhang, Xiao-Yu Du, Ying-Jian Zhang   +4 more
doaj   +3 more sources

Effect of Reaction Time and Stability Properties of Gold Nanoparticles Synthesized by p-Aminobenzoic Acid and p-Aminosalicylic Acid

Indonesian Journal of Chemistry, 2020
In this work, we determined the influenced of the reaction time at the synthesis of gold nanoparticles (AuNPs) by p-aminosalicylic acid and p-aminobenzoic acid as reducing agent.
Abdul Aji, Sri Juari Santosa, Eko Sri Kunarti   +2 more
doaj   +2 more sources

Significance of 5-Aminosalicylic Acid Intolerance in the Clinical Management of Ulcerative Colitis.

Digestion, 2023
Background: Two major types of 5-aminosalicylic acid (5-ASA)-containing preparations, namely, mesalazine/5-ASA and sulfasalazine (SASP), are currently used as first-line therapy for ulcerative colitis.
Mikami Y, Tsunoda J, Suzuki S, Mizushima I, Kiyohara H, Kanai T.   +5 more
europepmc   +2 more sources

Synthesis of Gold Nanoparticles Using p-Aminobenzoic Acid and p-Aminosalicylic Acid as Reducing Agent

Indonesian Journal of Chemistry, 2019
Synthesis of gold nanoparticles (AuNPs) by reduction of HAuCl4 with p-aminobenzoic acid and p-aminosalicylic acid as a reducing agent was investigated. This work was conducted in order to determine the optimum condition of AuNPs synthesis and examine the
Abdul Aji, Eko Sri Kunarti, Sri Juari Santosa   +2 more
doaj   +2 more sources

5-aminosalicylic acid suppresses osteoarthritis through the OSCAR-PPARγ axis. [PDF]

Nat Commun
Osteoarthritis (OA) is a progressive and irreversible degenerative joint disease that is characterized by cartilage destruction, osteophyte formation, subchondral bone remodeling, and synovitis.
Kim J, Ryu G, Seo J, Go M, Kim G, Yi S, Kim S, Lee H, Lee JY, Kim HS, Park MC, Shin DH, Shim H, Kim W, Lee SY.   +14 more
europepmc   +2 more sources

Aminosalicylic Acid [PDF]

Definitions, 2020
An analog of para-aminobenzoic acid (PABA) with antitubercular activity. Aminosalicylic acid exerts its bacteriostatic activity against Mycobacterium tuberculosis by competing with PABA for enzymes involved in folate synthesis, thereby suppressing growth
openaire   +2 more sources

Sustained release of 5-aminosalicylic acid from azoreductase-responsive polymeric prodrugs for prolonged colon-targeted colitis therapy. [PDF]

J Nanobiotechnology
Ulcerative colitis (UC) is a challenging inflammatory gastrointestinal disorder, whose therapies encounter limitations in overcoming insufficient colonic retention and rapid systemic clearance.
Tang S, Wang W, Wang Y, Gao Y, Dai K, Zhang W, Wu X, Yuan X, Jin C, Zan X, Zhu L, Geng W.   +11 more
europepmc   +2 more sources

Synthesis and intestinal metabolism of ursodeoxycholic acid conjugate with an antiinflammatory agent, 5-aminosalicylic acid

Journal of Lipid Research, 1998
5-Aminosalicylic acid conjugate of ursodeoxycholic acid was synthesized in above 90% yield by adding a basic solution of 5-aminosalicylic acid into the mixed anhydride formed with ursodeoxycholic acid and ethyl chloroformate.
Ashok K. Batta, G. Stephen Tint, Guorong Xu, Sarah Shefer, Gerald Salen   +4 more
doaj   +3 more sources

Prospective Questionnaire Survey on Adherence to Oral 5‐Aminosalicylic Acid in Patients With Ulcerative Colitis [PDF]

JGH Open
Background Adherence to 5‐aminosalicylic acid (5‐ASA), an anchor drug for ulcerative colitis (UC), affects remission maintenance. This study aimed to investigate the current status of adherence to 5‐ASA and identify the factors associated with adherence.
Tsuyoshi Beppu, Fumihito Hirai, Kensei Ohtsu, Masahiro Kishi, Teruyuki Takeda, Shigeyoshi Yasukawa, Noritaka Takatsu, Takashi Hisabe, Toshiharu Ueki, Kenshi Yao   +9 more
doaj   +2 more sources

Perimyocarditis in a Patient with Ulcerative Colitis Treated with 5-Aminosalicylic Acid [PDF]

The Korean Journal of Gastroenterology
5-Aminosalicylic acid (5-ASA) is recommended for managing ulcerative colitis. Common adverse effects associated with 5-ASA include gastrointestinal disorders, headaches, and skin rashes.
Hye Young Lee, Dong Hoon Baek
doaj   +2 more sources