Results 1 to 10 of about 15,403 (210)

Synthesis and intestinal metabolism of ursodeoxycholic acid conjugate with an antiinflammatory agent, 5-aminosalicylic acid

Journal of Lipid Research, 1998
5-Aminosalicylic acid conjugate of ursodeoxycholic acid was synthesized in above 90% yield by adding a basic solution of 5-aminosalicylic acid into the mixed anhydride formed with ursodeoxycholic acid and ethyl chloroformate.
Ashok K. Batta, G. Stephen Tint, Guorong Xu, Sarah Shefer, Gerald Salen   +4 more
doaj   +3 more sources

Comparison of effects of aminosalicylic acid, glucocorticoids and immunosuppressive agents on the expression of multidrug-resistant genes in ulcerative colitis [PDF]

Scientific Reports, 2022
To compare the effects of aminosalicylic acid, glucocorticoids and immunosuppressants on the expression levels of multidrug resistance genes in patients with ulcerative colitis (UC), with the aim of providing a theoretical and therapeutic basis for the ...
Yan Chen, Ping Wang, Yin Zhang, Xiao-Yu Du, Ying-Jian Zhang   +4 more
doaj   +2 more sources

Cyanidin-3-glucoside suppresses cytokine-induced inflammatory response in human intestinal cells: comparison with 5-aminosalicylic acid. [PDF]

PLoS ONE, 2013
The potential use of polyphenols in the prevention and treatment of chronic inflammatory diseases has been extensively investigated although the mechanisms involved in cellular signaling need to be further elucidated.
Diana Serra, Joana Paixão, Carla Nunes, Teresa C P Dinis, Leonor M Almeida   +4 more
doaj   +1 more source

Spectrophotometric Determination of para aminosalicylic acid in Serum Blood and Urin By Oxidative Coupling With 4-Amino Antipyrine and Study The Inhibition of Aldose Reductase Enzyme

Tikrit Journal of Pure Science, 2023
This work includes a new spectrophotometric method for the determination para aminosalicylic acid in aqueous medium based on the oxidation by  NaIO4 and coupling with 4-Amino Antipyrine producing a red dye soluble in water  and of גmax of 516 nm.
Asma'a H. Shakir
doaj   +1 more source

Repurposing a Drug Targeting Inflammatory Bowel Disease for Lowering Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background The gut and gut microbiota, which were previously neglected in blood pressure regulation, are becoming increasingly recognized as factors contributing to hypertension. Diseases affecting the gut such as inflammatory bowel disease (IBD) present
Xue Mei, Blair Mell, Ishan Manandhar, Sachin Aryal, Ramakumar Tummala, Jun Kyoung, Tao Yang, Bina Joe   +7 more
doaj   +1 more source

Effect of Reaction Time and Stability Properties of Gold Nanoparticles Synthesized by p-Aminobenzoic Acid and p-Aminosalicylic Acid

Indonesian Journal of Chemistry, 2020
In this work, we determined the influenced of the reaction time at the synthesis of gold nanoparticles (AuNPs) by p-aminosalicylic acid and p-aminobenzoic acid as reducing agent.
Abdul Aji, Sri Juari Santosa, Eko Sri Kunarti   +2 more
doaj   +1 more source

Synthesis of a novel PEGylated colon-specific azo-based 4- aminosalicylic acid prodrug [PDF]

Iranian Journal of Basic Medical Sciences, 2020
Objective(s): 4-aminosalicylic acid (4-ASA) is an isomer of mesalazine that has recently been shown to be effective against inflammatory bowel disease (IBD), and more specifically, ulcerative colitis. However, the majority of orally administered 4-ASA is
Fatemeh Sadeghi, Atie Eidizade, Farinaz Saremnejad, Farzin Hadizadeh, Elham Khodaverdi, Abbas Akhgari   +5 more
doaj   +1 more source

Resveratrol modulates cytokine-induced Jak/STAT activation more efficiently than 5-aminosalicylic acid: an in vitro approach. [PDF]

PLoS ONE, 2014
Many advances have been recently made focused on the valuable help of dietary polyphenols in chronic inflammatory diseases. On the other hand, current treatment options for intestinal bowel disease patients are unsatisfying and, for this reason, it is ...
Diana Serra, Ana T Rufino, Alexandrina F Mendes, Leonor M Almeida, Teresa C P Dinis   +4 more
doaj   +1 more source

Mesalazine induced focal segmental glomerulosclerosis in a patient with ulcerative colitis

Saudi Journal of Kidney Diseases and Transplantation, 2020
Focal segmental glomerulosclerosis (FSGS) and other glomerulonephritis due to the use of 5-aminosalicylic acid derivatives have been reported in the literature. A 38-year-old male who had been using mesalazine for four years because of ulcerative colitis
Fatih Yilmaz, Bora Uslu, Bahar Akkaya, Ramazan Cetinkaya   +3 more
doaj   +1 more source

Amino Acid Derivatives of Aminosalicylic Acids† [PDF]

Journal of the American Pharmaceutical Association (Scientific ed.), 1953
Abstract A series of amide derivatives of 3‐, 4‐, and 5‐aminosalicylic acids with α‐amino acids has been prepared by a method which involves amide formation between the carboxyl group of the aminosalicylic acid and the amino group of the amino acid. The stability as well as the ease of formation of the compounds was increased by utilization of the O ...
W O, FOYE, R L, HULL
openaire   +2 more sources